World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
84
Citations
66652
World Ranking
1330
National Ranking
28

Overview

Cheng Li is affiliated with Peking University in China, focusing research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several specialized subfields, including Molecular Biology, Immunology, Cancer Research, Oncology, and Pulmonary and Respiratory Medicine. This interdisciplinary approach supports research into complex biological mechanisms across health and disease contexts.

The scientist's research addresses a variety of main topics such as Genomics and Chromatin Dynamics, RNA Research and Splicing, Pluripotent Stem Cells Research, CRISPR and Genetic Engineering, RNA modifications and cancer, Cancer-related molecular mechanisms research, and Single-cell and spatial transcriptomics. These topics reflect a significant focus on the molecular and genetic regulatory systems influencing cellular function and pathology.

Cheng Li has contributed to numerous publications in notable venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Research
  • Cell Reports
  • Cell stem cell
  • Nature Communications

Selected papers showcasing their recent work include:

  • "Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection," published in 2020 in Nature Immunology
  • "Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice," published in 2020 in Cell Research
  • "Chemical reprogramming of human somatic cells to pluripotent stem cells," published in 2022 in Nature
  • "Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody," published in 2020 in bioRxiv (Cold Spring Harbor Laboratory)
  • "Genome-wide analyses of chromatin interactions after the loss of Pol I, Pol II, and Pol III," published in 2020 in Genome Biology

Frequent collaborators include:

  • Hongkui Deng
  • Yujie Sun
  • Yingping Hou
  • Jingyang Guan
  • Yulin Lyu

This network of coauthors suggests active involvement in collaborative research projects integrating various molecular and cellular biology disciplines.

Best Publications

  • Bioconductor: open software development for computational biology and bioinformatics

    Robert C Gentleman;Vincent J Carey;Douglas M. Bates;B.M. Bolstad

  • GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses.

    Zefang Tang;Chenwei Li;Boxi Kang;Ge Gao

  • Adjusting batch effects in microarray expression data using empirical Bayes methods

    W. Evan Johnson;Cheng Li;Ariel Rabinovic

  • Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection

    Cheng Li;Wing Hung Wong

  • Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

    Arindam Bhattacharjee;William G. Richards;Jane Staunton;Cheng Li

  • Gene regulation and DNA damage in the ageing human brain.

    Tao Lu;Ying Pan;Shyan Yuan Kao;Cheng Li

  • Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

    Levi A. Garraway;Hans R. Widlund;Mark A. Rubin;Gad Getz

  • Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia.

    Yaron Hakak;John R. Walker;Cheng Li;Wing Hung Wong

  • Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application

    Cheng Li;Wing Hung Wong

  • Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection

    Xuemei Xie;Qiang Shi;Peng Wu;Xiaoyu Zhang

  • An Integrated View of Copy Number and Allelic Alterations in the Cancer Genome Using Single Nucleotide Polymorphism Arrays

    Xiaojun Zhao;Cheng Li;J. Guillermo Paez;Koei Chin

  • Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

    Marta M. Lipinski;Bin Zheng;Tao Lu;Zhenyu Yan

  • Highly parallel identification of essential genes in cancer cells

    Biao Luo;Hiu Wing Cheung;Aravind Subramanian;Tanaz Sharifnia

  • Two supervised learning approaches for name disambiguation in author citations

    Hui Han;Lee Giles;Hongyuan Zha;Cheng Li

  • Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data

    Cheng Li;Wing Hung Wong

  • dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data

    Ming Lin;Lee-Jen Wei;William R. Sellers;Marshall Lieberfarb

  • Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency

    Yang Yang;Bei Liu;Jun Xu;Jinlin Wang

  • Genome coverage and sequence fidelity of ϕ29 polymerase‐based multiple strand displacement whole genome amplification

    J. Guillermo Paez;Ming Lin;Rameen Beroukhim;Jeffrey C. Lee

  • CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia

    Lei Xu;Jun Wang;Yulin Liu;Liangfu Xie

  • Homozygous Deletions and Chromosome Amplifications in Human Lung Carcinomas Revealed by Single Nucleotide Polymorphism Array Analysis

    Xiaojun Zhao;Barbara A. Weir;Thomas Louis LaFramboise;Ming Lin

Frequent Co-Authors

Nikhil C. Munshi
Nikhil C. Munshi Harvard University
Wing Hung Wong
Wing Hung Wong Stanford University
Matthew Meyerson
Matthew Meyerson Harvard University
Kenneth C. Anderson
Kenneth C. Anderson Harvard University
Yu-Tzu Tai
Yu-Tzu Tai Harvard University
Rameen Beroukhim
Rameen Beroukhim Harvard University
William R. Sellers
William R. Sellers Harvard University
Hongkui Deng
Hongkui Deng Peking University
Faith E. Davies
Faith E. Davies New York University Langone Medical Center

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