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Hongkui Deng

Hongkui Deng

D-Index & Metrics

Molecular Biology

D-Index
74
Citations
30525
World Ranking
1214
National Ranking
22

Overview

Hongkui Deng is primarily affiliated with Peking University in China. Their research spans broadly across the fields of Biochemistry, Genetics, and Molecular Biology, with a significant focus on Medicine. Within these domains, Deng has produced 85 publications related to Biochemistry, Genetics and Molecular Biology, and 63 publications related to Medicine.

Their subfields of study include Molecular Biology, Oncology, Surgery, Immunology, and Biomedical Engineering. The main topics addressed in their research involve Pluripotent Stem Cells Research, CRISPR and Genetic Engineering, Pancreatic function and diabetes, CAR-T cell therapy research, Immune Cell Function and Interaction, RNA Interference and Gene Delivery, and 3D Printing in Biomedical Research.

Hongkui Deng has collaborated frequently with a number of coauthors, including:

  • Cheng Li
  • Yufang Bi
  • Zachary T. Bloomgarden
  • Robert Ćhilton
  • Youfei Guan

The scientist's recent papers illustrate a focus on cellular reprogramming, diabetes treatment, and tissue regeneration. Notable recent publications include:

  • Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice, 2020, Cell Research
  • Chemical reprogramming of human somatic cells to pluripotent stem cells, 2022, Nature
  • Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient, 2024, Cell
  • Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates, 2022, Nature Medicine
  • Establishment of intestinal organoid cultures modeling injury-associated epithelial regeneration, 2021, Cell Research

The frequent venues for Deng's publications include journals focusing on diabetes and cellular research such as:

  • Journal of Diabetes
  • Cell Research
  • Cell stem cell
  • Cell
  • Stem Cell Reports

Best Publications

  • Identification of a major co-receptor for primary isolates of HIV-1

    H Deng;R Liu;W Ellmeier;S Choe

  • Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds

    Pingping Hou;Yanqin Li;Xu Zhang;Chun Liu

  • Expression cloning of new receptors used by simian and human immunodeficiency viruses

    HongKui Deng;Derya Unutmaz;Vineet N. KewalRamani;Dan R. Littman

  • In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression.

    Gabriella Scarlatti;Eleonora Tresoldi;Åsa Björndal;Robert Fredriksson

  • Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype.

    Åsa Björndal;Hongkui Deng;Marianne Jansson;José R. Fiore

  • Directed differentiation of human embryonic stem cells into functional hepatic cells.

    Jun Cai;Yang Zhao;Yanxia Liu;Fei Ye

  • Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells

    Donghui Zhang;Wei Jiang;Meng Liu;Xin Sui

  • Generation of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors

    Wenlin Li;Wei Wei;Saiyong Zhu;Jinliang Zhu

  • Generation of Induced Pluripotent Stem Cells from Adult Rhesus Monkey Fibroblasts

    Haisong Liu;Fangfang Zhu;Jun Yong;Pengbo Zhang

  • Two supporting factors greatly improve the efficiency of human iPSC generation.

    Yang Zhao;Xiaolei Yin;Han Qin;Fangfang Zhu

  • Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells.

    Zhihua Song;Jun Cai;Yanxia Liu;Dongxin Zhao

  • Hallmarks of pluripotency

    Alejandro De Los Angeles;Francesco Ferrari;Ruibin Xi;Ruibin Xi;Yuko Fujiwara

  • Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency

    Yang Yang;Bei Liu;Jun Xu;Jinlin Wang

  • Direct Lineage Reprogramming: Strategies, Mechanisms, and Applications

    Jun Xu;Yuanyuan Du;Hongkui Deng

  • Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons.

    Xiang Li;Xiaohan Zuo;Junzhan Jing;Yantao Ma

  • In vitro derivation of functional insulin-producing cells from human embryonic stem cells.

    Wei Jiang;Yan Shi;Yan Shi;Dongxin Zhao;Song Chen

  • Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules

    Yanqin Li;Qiang Zhang;Xiaolei Yin;Weifeng Yang

  • CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia

    Lei Xu;Jun Wang;Yulin Liu;Liangfu Xie

  • Small Molecules Blocking the Entry of Severe Acute Respiratory Syndrome Coronavirus into Host Cells

    Ling Yi;Zhengquan Li;Kehu Yuan;Xiuxia Qu

  • Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells

    Pengbo Zhang;Jian Li;Zhijia Tan;Chengyan Wang

Frequent Co-Authors

Yang Zhao
Yang Zhao Chinese Academy of Sciences
Dan R. Littman
Dan R. Littman New York University
Eli E. Sercarz
Eli E. Sercarz Torrey Pines Institute For Molecular Studies
Duanqing Pei
Duanqing Pei Westlake University
George Q. Daley
George Q. Daley Boston Children's Hospital
Georg Herrler
Georg Herrler University of Veterinary Medicine Vienna
Konrad Hochedlinger
Konrad Hochedlinger Harvard University
Yuko Fujiwara
Yuko Fujiwara Harvard University
Marius Wernig
Marius Wernig Stanford University
Derya Unutmaz
Derya Unutmaz University of Connecticut

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