World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
30391
World Ranking
18169
National Ranking
7423

Overview

Christine Ambrose is affiliated with Biogen in the United States and has contributed to research primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their work spans subfields including Oncology, Genetics, Molecular Biology, Immunology, and Biomedical Engineering, with a focus on various topics related to cellular therapies and gene expression.

The scientist has conducted extensive research on CAR-T cell therapy, resulting in notable publications such as:

  • "Anti-CD19 CAR T cells potently redirected to kill solid tumor cells," 2021, published in PLoS ONE
  • "Anti-CD19 CAR T cells potently redirected to kill solid tumor cells," 2020, published in bioRxiv (Cold Spring Harbor Laboratory)

Other relevant papers in related domains, which include contributions from close collaborators, include:

  • "CAR-T Engager proteins optimize anti-CD19 CAR-T cell therapies for lymphoma," 2022, published in OncoImmunology
  • "A CD19-Anti-ErbB2 scFv Engager Protein Enables CD19-Specific CAR T Cells to Eradicate ErbB2+ Solid Cancer," 2023, published in Cells
  • "133 Development of novel cellular therapeutics for metastatic and primary CNS malignancies," 2020, published in Regular and Young Investigator Award Abstracts

The frequent coauthors working alongside Christine Ambrose include Paul D. Rennert, Roy R. Lobb, Lihe Su, Lan Wu, and Fay J. Dufort. Their collaboration is reflected across multiple publications, indicating a focused research network.

The principal venues of publication for Christine Ambrose's work are:

  • Regular and Young Investigator Award Abstracts
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE
  • OncoImmunology
  • Cells

Christine Ambrose's main research topics cover:

  • CAR-T cell therapy research
  • Virus-based gene therapy research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Biosimilars and Bioanalytical Methods
  • Nanowire Synthesis and Applications
  • Monoclonal and Polyclonal Antibodies Research
  • Immunotherapy and Immune Responses

Best Publications

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

    Marcy E. MacDonald;Christine M. Ambrose;Mabel P. Duyao;Richard H. Myers

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

    M Shah;N Datson;L Srinidhi;VP Stanton

  • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations.

    Fabienne Mackay;Stephen A. Woodcock;Pornsri Lawton;Christine Ambrose

  • A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

    James A. Trofatter;Mia M. MacCollin;Joni L. Rutter;Jill R. Murrell

  • BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.

    Pascal Schneider;Fabienne Mackay;Véronique Steiner;Kay Hofmann

  • Trinucleotide repeat length instability and age of onset in Huntington's disease

    M Duyao;C Ambrose;R Myers;A Novelletto

  • BAFF-R, a Newly Identified TNF Receptor That Specifically Interacts with BAFF

    Jeffrey S. Thompson;Sarah A. Bixler;Fang Qian;Kalpit Vora

  • Identification of a palmitic acid-modified form of human Sonic hedgehog.

    R. B. Pepinsky;Chenhui Zeng;Dingyi Wen;P. Rayhorn

  • Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human

    Claudia Bossen;Karine Ingold;Aubry Tardivel;Jean-Luc Bodmer

  • BAFF selectively enhances the survival of plasmablasts generated from human memory B cells

    Danielle T. Avery;Susan L. Kalled;Julia I. Ellyard;Christine Ambrose

  • TWEAK induces liver progenitor cell proliferation

    Aniela Jakubowski;Christine Ambrose;Michael Parr;John M. Lincecum

  • Baff Binds to the Tumor Necrosis Factor Receptor–Like Molecule B Cell Maturation Antigen and Is Important for Maintaining the Peripheral B Cell Population

    Jeffrey S. Thompson;Pascal Schneider;Susan L. Kalled;LiChun Wang

  • A Soluble Form of B Cell Maturation Antigen, a Receptor for the Tumor Necrosis Factor Family Member April, Inhibits Tumor Cell Growth

    Paul Rennert;Pascal Schneider;Teresa G. Cachero;Jeffrey Thompson

  • Structure and expression of the Huntington's disease gene: Evidence against simple inactivation due to an expanded CAG repeat

    Christine M. Ambrose;Mabel P. Duyao;Glenn Barnes;Gillian P. Bates

  • De novo expansion of a (CAG)n repeat in sporadic Huntington's disease.

    R H Myers;M E MacDonald;W J Koroshetz;M P Duyao

  • Huntington's disease gene: Regional and cellular expression in brain of normal and affected individuals

    G B Landwehrmeyer;S M McNeil;L S Dure th;P Ge

  • Characterization of the G Protein-coupled Receptor Kinase GRK4 IDENTIFICATION OF FOUR SPLICE VARIANTS

    Richard T. Premont;Alexander D. Macrae;Robert H. Stoffel;Namjin Chung

  • The TNF family members BAFF and APRIL: the growing complexity.

    Fabienne Mackay;Christine Ambrose

  • Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes.

    J L Browning;I D Sizing;P Lawton;P R Bourdon

  • Gametic but not somatic instability of CAG repeat length in Huntington's disease.

    M. E. MacDonald;G. Barnes;J. Srinidhi;M. P. Duyao

Frequent Co-Authors

Pascal Schneider
Pascal Schneider University of Lausanne
Fabienne Mackay
Fabienne Mackay QIMR Berghofer Medical Research Institute
Marcy E. MacDonald
Marcy E. MacDonald Harvard University
James F. Gusella
James F. Gusella Harvard University
Roy R. Lobb
Roy R. Lobb Biogen (United States)
Jeffrey L. Browning
Jeffrey L. Browning Boston University
Jürg Tschopp
Jürg Tschopp University of Lausanne
John J. Wasmuth
John J. Wasmuth University of California, Irvine
Gillian P. Bates
Gillian P. Bates University College London

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