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Jeffrey L. Browning

Jeffrey L. Browning

D-Index & Metrics

Microbiology

D-Index
82
Citations
32675
World Ranking
1038
National Ranking
476

Overview

Jeffrey L. Browning is affiliated with Boston University in the United States and focuses primarily on medicine, with research spanning multiple subfields including immunology, epidemiology, rheumatology, radiology, nuclear medicine and imaging, and surgery. Their work addresses a variety of medical topics, prominently those related to systemic sclerosis and related diseases, pneumonia and respiratory infections, immune cell function and interaction, T-cell and B-cell immunology, dermatologic treatments and research, liver disease diagnosis and treatment, and cardiovascular disease and adiposity.

Several recent publications illustrate the scope of their research interests. These include:

  • Lung-resident memory B cells protect against bacterial pneumonia (2021, Journal of Clinical Investigation)
  • Immunofibroblasts regulate LTα3 expression in tertiary lymphoid structures in a pathway dependent on ICOS/ICOSL interaction (2022, Communications Biology)
  • Prolonged nonobstructive urinary retention induced by tibial nerve stimulation in cats (2020, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology)
  • B cells in the pneumococcus-infected lung are heterogeneous and require CD4+ T cell help including CD40L to become resident memory B cells (2024, Frontiers in Immunology)
  • Amelioration of Murine Autoimmune Pancreatitis by Targeted LTβR Inhibition and Anti-CD20 Treatment (2020, ImmunoHorizons)

Frequent coauthors of Browning include James A. de Lemos, Ian J. Neeland, Kimberly A. Barker, Anukul T. Shenoy, and C. Lyon De Ana. These collaborations suggest interdisciplinary engagement across various aspects of immunology and clinical research.

Jeffrey L. Browning's work appears regularly in several publication venues, notably:

  • The Journal of Immunology
  • Circulation
  • Journal of Clinical Investigation
  • Communications Biology
  • Frontiers in Immunology

The researcher's contributions lie heavily in immunological aspects of disease, particularly involving immune cell types such as B cells and T cells, which is reflected in their focus on immune cell function and interaction as well as detailed studies on memory B cells in pulmonary infections. They also engage with clinical implications linked to systemic sclerosis and autoimmune diseases.

Best Publications

  • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations.

    Fabienne Mackay;Stephen A. Woodcock;Pornsri Lawton;Christine Ambrose

  • BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.

    Pascal Schneider;Fabienne Mackay;Véronique Steiner;Kay Hofmann

  • A chemokine-driven positive feedback loop organizes lymphoid follicles

    K M Ansel;V N Ngo;P L Hyman;S A Luther

  • BAFF AND APRIL: a tutorial on B cell survival.

    Fabienne Mackay;Pascal Schneider;Paul Rennert;Jeffrey Browning

  • BAFF-R, a Newly Identified TNF Receptor That Specifically Interacts with BAFF

    Jeffrey S. Thompson;Sarah A. Bixler;Fang Qian;Kalpit Vora

  • Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

    Julie Lucifora;Yuchen Xia;Florian Reisinger;Ke Zhang

  • TWEAK, a New Secreted Ligand in the Tumor Necrosis Factor Family That Weakly Induces Apoptosis

    Yves Chicheportiche;Paul R. Bourdon;Haoda Xu;Yen-Ming Hsu

  • BAFF: A fundamental survival factor for B cells

    Fabienne Mackay;Jeffrey L. Browning

  • BAFF mediates survival of peripheral immature B lymphocytes.

    Marcel Batten;Joanna Groom;Teresa G. Cachero;Fang Qian

  • Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity.

    Barbara P. Wallner;Robert J. Mattaliano;Catherine Hession;Richard L. Cate

  • Lymphotoxin β, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface

    Jeffrey L. Browning;Apinya Ngam-ek;Pornsri Lawton;Janice DeMarinis

  • Distinct Roles in Lymphoid Organogenesis for Lymphotoxins α and β Revealed in Lymphotoxin β–Deficient Mice

    Pandelakis A Koni;Rosalba Sacca;Pornsri Lawton;Jeffrey L Browning

  • Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen.

    Vu N. Ngo;Heinrich Korner;Michael D. Gunn;Kerstin N. Schmidt

  • Two human 35 kd inhibitors of phospholipase A2 are related to substrates of pp60v-src and of the epidermal growth factor receptor/kinase

    Kuo-Sen Huang;Barbara P. Wallner;Robert J. Mattaliano;Richard Tizard

  • TAJ/TROY, an Orphan TNF Receptor Family Member, Binds Nogo-66 Receptor 1 and Regulates Axonal Regeneration

    Zhaohui Shao;Jeffrey L. Browning;Xinhua Lee;Martin L. Scott

  • Five distinct calcium and phospholipid binding proteins share homology with lipocortin I.

    R B Pepinsky;R Tizard;R J Mattaliano;L K Sinclair

  • Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs.

    P D Rennert;J L Browning;R Mebius;F Mackay

  • Baff Binds to the Tumor Necrosis Factor Receptor–Like Molecule B Cell Maturation Antigen and Is Important for Maintaining the Peripheral B Cell Population

    Jeffrey S. Thompson;Pascal Schneider;Susan L. Kalled;LiChun Wang

  • A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma

    Johannes Haybaeck;Nicolas Zeller;Monika Julia Wolf;Achim Weber

  • TRAMP, a Novel Apoptosis-Mediating Receptor with Sequence Homology to Tumor Necrosis Factor Receptor 1 and Fas(Apo-1/CD95)

    Jean-Luc Bodmer;Kim Burns;Pascal Schneider;Kay Hofmann

Frequent Co-Authors

Fabienne Mackay
Fabienne Mackay QIMR Berghofer Medical Research Institute
Pascal Schneider
Pascal Schneider University of Lausanne
Jürg Tschopp
Jürg Tschopp University of Lausanne
Carl F. Ware
Carl F. Ware Sanford Burnham Prebys Medical Discovery Institute
Mathias Heikenwalder
Mathias Heikenwalder German Cancer Research Center
R. Blake Pepinsky
R. Blake Pepinsky Biogen (United States)
Christine Ambrose
Christine Ambrose Biogen (United States)
Robert Lafyatis
Robert Lafyatis University of Pittsburgh
Achim Weber
Achim Weber University of Zurich
Roberto Chiarle
Roberto Chiarle Harvard University

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