Alan H. Sharp

Overview

Best Publications

• FORMATION OF NEURONAL INTRANUCLEAR INCLUSIONS UNDERLIES THE NEUROLOGICAL DYSFUNCTION IN MICE TRANSGENIC FOR THE HD MUTATION

  Stephen W Davies;Mark Turmaine;Barbara A Cozens;Marian DiFiglia

  3435
  Citations

• Intranuclear Inclusions and Neuritic Aggregates in Transgenic Mice Expressing a Mutant N-Terminal Fragment of Huntingtin

  Gabriele Schilling;Mark W. Becher;Alan H. Sharp;Hyder A. Jinnah

  922
  Citations

• Sequence and expression of MRNAs encoding the α1 and α2 subunits of a DHP-sensitive calcium channel

  Steven B. Ellis;Mark E. Williams;Nancy R. Ways;Robert Brenner

  787
  Citations

• A huntingtin-associated protein enriched in brain with implications for pathology

  Xiao-Jiang Li;Shi-Hua Li;Alan H. Sharp;Frederick C. Nucifora

  772
  Citations

• Dominant phenotypes produced by the HD mutation in STHdhQ111 striatal cells

  Flavia Trettel;Dorotea Rigamonti;Paige Hilditch-Maguire;Vanessa C. Wheeler

  696
  Citations

• Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions.

  Simone Engelender;Zachary Kaminsky;Xin Guo;Alan H. Sharp

  632
  Citations

• Widespread expression of Huntington's disease gene (IT15) protein product

  Alan H. Sharp;Scott J. Loev;Gabriele Schilling;Shi Hua Li

  623
  Citations

• Expansion of a novel CAG trinucleotide repeat in the 5' region of PPP2R2B is associated with SCA12.

  Susan E. Holmes;Elizabeth E. O'Hearn;Melvin G. McInnis;Daniel A. Gorelick-Feldman

  596
  Citations

• Intranuclear Neuronal Inclusions in Huntington's Disease and Dentatorubral and Pallidoluysian Atrophy: Correlation between the Density of Inclusions andIT15CAG Triplet Repeat Length

  Mark W. Becher;Joyce A. Kotzuk;Alan H. Sharp;Stephen W. Davies

  595
  Citations

• Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization

  Akira Sawa;Gordon W. Wiegand;Jillian Cooper;Russell L. Margolis

  526
  Citations

• Differential immunohistochemical localization of inositol 1,4,5- trisphosphate- and ryanodine-sensitive Ca2+ release channels in rat brain

  AH Sharp;PS McPherson;TM Dawson;C Aoki

  520
  Citations

• Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells.

  Cheryl L. Wellington;Roshni Singaraja;Lisa Ellerby;Jane Savill

  462
  Citations

• Truncated N-Terminal Fragments of Huntingtin with Expanded Glutamine Repeats form Nuclear and Cytoplasmic Aggregates in Cell Culture

  Jillian K. Cooper;Gabriele Schilling;Matthew F. Peters;William J. Herring

  457
  Citations

• The biochemistry and molecular biology of the dihydropyridine-sensitive calcium channel

  Kevin P. Campbell;Albert T. Leung;Alan H. Sharp

  445
  Citations

• Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin.

  Simone Engelender;Alan H. Sharp;Veronica Colomer;Mariko K. Tokito

  422
  Citations

• Structural characterization of the dihydropyridine-sensitive calcium channel alpha 2-subunit and the associated delta peptides.

  S D Jay;A H Sharp;S D Kahl;T S Vedvick

  399
  Citations

• Lymphocyte Apoptosis: Mediation by Increased Type 3 Inositol 1,4,5-Trisphosphate Receptor

  Adil A. Khan;Mark J. Soloski;Alan H. Sharp;Gabriele Schilling

  329
  Citations

• Differential localization of phosphoinositide-linked metabotropic glutamate receptor (mGluR1) and the inositol 1,4,5-trisphosphate receptor in rat brain

  Majid Fotuhi;A. H. Sharp;C. E. Glatt;P. M. Hwang

  285
  Citations

• Identification and characterization of the dihydropyridine-binding subunit of the skeletal muscle dihydropyridine receptor.

  A H Sharp;T Imagawa;A T Leung;K P Campbell

  242
  Citations

• Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins

  Jonathan D. Wood;Joseph Yuan;Russell L. Margolis;Veronica Colomer

  237
  Citations