World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
62
Citations
21060
World Ranking
3461
National Ranking
1599

Overview

What is he best known for?

The fields of study he is best known for:

  • Neuron
  • Neurotransmitter
  • Neuroscience

His scientific interests lie mostly in Neuroscience, Synaptic plasticity, Neurotransmission, Long-term potentiation and Metaplasticity. His work carried out in the field of Neuroscience brings together such families of science as Glutamate receptor and Long-term depression. His Neurotransmission study combines topics from a wide range of disciplines, such as Rab3A GTP-Binding Protein, Hippocampal mossy fiber, Mossy fiber and Cell biology.

His Cell biology research includes themes of Synapsin, Active zone and Neurotransmitter. His Long-term potentiation study integrates concerns from other disciplines, such as NMDA receptor and Protein kinase A. His Metaplasticity research is multidisciplinary, incorporating perspectives in Synaptic fatigue and Endocannabinoid system.

His most cited work include:

  • Mice Lacking α-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine System (1431 citations)
  • ENDOCANNABINOID-MEDIATED SYNAPTIC PLASTICITY IN THE CNS (629 citations)
  • Heterosynaptic LTD of Hippocampal GABAergic Synapses: A Novel Role of Endocannabinoids in Regulating Excitability (559 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Neuroscience, Synaptic plasticity, Cell biology, Neurotransmission and Long-term potentiation. Pablo E. Castillo interconnects Metaplasticity and Long-term depression in the investigation of issues within Neuroscience. His research in the fields of Synaptic fatigue overlaps with other disciplines such as Translation.

His studies deal with areas such as Synapse, Active zone, Biochemistry and Neurotransmitter as well as Cell biology. His work in Neurotransmission is not limited to one particular discipline; it also encompasses Glutamate receptor. His Long-term potentiation research focuses on Hippocampal mossy fiber and how it relates to Parallel fiber.

He most often published in these fields:

  • Neuroscience (76.67%)
  • Synaptic plasticity (40.00%)
  • Cell biology (29.17%)

What were the highlights of his more recent work (between 2017-2021)?

  • Neuroscience (76.67%)
  • Inhibitory postsynaptic potential (20.00%)
  • Postsynaptic potential (16.67%)

In recent papers he was focusing on the following fields of study:

His main research concerns Neuroscience, Inhibitory postsynaptic potential, Postsynaptic potential, Hippocampal formation and Cell biology. His Neuroscience research incorporates elements of Synaptic plasticity, Long-term potentiation, Neurotransmission and Metabotropic glutamate receptor. His biological study focuses on Metaplasticity.

Within one scientific family, Pablo E. Castillo focuses on topics pertaining to Hippocampus under Neurotransmission, and may sometimes address concerns connected to Excitatory postsynaptic potential, Kainate receptor, Glutamate receptor and Kainic acid. His research in Hippocampal formation focuses on subjects like Endocannabinoid system, which are connected to Prefrontal cortex. His work focuses on many connections between Cell biology and other disciplines, such as Protein biosynthesis, that overlap with his field of interest in Cannabinoid receptor.

Between 2017 and 2021, his most popular works were:

  • Long-Term Plasticity of Neurotransmitter Release: Emerging Mechanisms and Contributions to Brain Function and Disease. (43 citations)
  • Npas4 Is a Critical Regulator of Learning-Induced Plasticity at Mossy Fiber-CA3 Synapses during Contextual Memory Formation (30 citations)
  • Modulation of NMDA Receptors by G-protein-coupled receptors: Role in Synaptic Transmission, Plasticity and Beyond. (5 citations)

In his most recent research, the most cited papers focused on:

  • Neuron
  • Neurotransmitter
  • Internal medicine

Neuroscience, Inhibitory postsynaptic potential, Hippocampal formation, Synaptic plasticity and Long-term potentiation are his primary areas of study. His Neuroscience research is multidisciplinary, incorporating elements of Metaplasticity and G protein-coupled receptor. His study in Inhibitory postsynaptic potential is interdisciplinary in nature, drawing from both Protein biosynthesis, Neurotransmitter, Neurotransmitter Agents and Cell biology.

His biological study spans a wide range of topics, including Postsynaptic potential and Cannabinoid receptor. His Synaptic plasticity research is multidisciplinary, relying on both Biological neural network, Neuroplasticity and Excitatory postsynaptic potential. The study incorporates disciplines such as Neuromodulation, Glutamatergic, NMDA receptor and Neurotransmission in addition to Long-term potentiation.

Best Publications

  • Mice Lacking α-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine System

    Asa Abeliovich;Yvonne Schmitz;Isabel Fariñas;Derek Choi-Lundberg

  • Endocannabinoid Signaling and Synaptic Function

    Pablo E. Castillo;Thomas J. Younts;Andrés E. Chávez;Yuki Hashimotodani

  • ENDOCANNABINOID-MEDIATED SYNAPTIC PLASTICITY IN THE CNS

    Vivien Chevaleyre;Kanji A. Takahashi;Pablo E. Castillo

  • Heterosynaptic LTD of Hippocampal GABAergic Synapses: A Novel Role of Endocannabinoids in Regulating Excitability

    Vivien Chevaleyre;Pablo E. Castillo

  • RIM1α forms a protein scaffold for regulating neurotransmitter release at the active zone

    Susanne Schoch;Pablo E. Castillo;Pablo E. Castillo;Tobias Jo;Konark Mukherjee

  • Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP

    Marc G. Weisskopf;Pablo E. Castillo;Robert A. Zalutsky;Roger A. Nicoll

  • Kainate receptors mediate a slow postsynaptic current in hippocampal CA3 neurons

    Pablo E. Castillo;Robert C. Malenka;Roger A. Nicoll

  • Endocannabinoid Signaling and Long-Term Synaptic Plasticity

    Boris D. Heifets;Pablo E. Castillo

  • Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

    Christophe Mulle;Andreas Sailer;Isabel Pérez-Otaño;Heather Dickinson-Anson

  • Double-knockout mice for α- and β-synucleins: Effect on synaptic functions

    Sreeganga Chandra;Francesco Fornai;Hyung Bae Kwon;Umar Yazdani

  • RIM1α is required for presynaptic long-term potentiation

    Pablo E. Castillo;Susanne Schoch;Frank Schmitz;Frank Schmitz;Thomas C. Südhof

  • Rab3A is essential for mossy fibre long-term potentiation in the hippocampus.

    Pablo E. Castillo;Pablo E. Castillo;Roger Janz;Thomas C. Südhof;Thanos Tzounopoulos

  • Synaptic plasticity of NMDA receptors: mechanisms and functional implications.

    David L Hunt;Pablo E Castillo

  • Heterosynaptic LTD of Hippocampal GABAergic Synapses A Novel Role of Endocannabinoids in Regulating Excitability

    Unknown

  • TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus

    Andrés E Chávez;Chiayu Q Chiu;Pablo E Castillo

  • Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology

    Manuela Polydoro;Christopher M. Acker;Karen Duff;Pablo E. Castillo

  • Synucleins regulate the kinetics of synaptic vesicle endocytosis.

    Karina J. Vargas;Sachin Makani;Taylor Davis;Christopher H. Westphal

  • The role of Ca2+ channels in hippocampal mossy fiber synaptic transmission and long-term potentiation.

    Pablo E. Castillo;Marc G. Weisskopf;Roger A. Nicoll

  • Protein kinase A regulates calcium permeability of NMDA receptors

    V Arvydas Skeberdis;Vivien Chevaleyre;C Geoffrey Lau;Jesse H Goldberg;Jesse H Goldberg

  • αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction

    Becket Greten-Harrison;Manuela Polydoro;Megumi Morimoto-Tomita;Ling Diao

  • Endocannabinoid-mediated metaplasticity in the hippocampus.

    Vivien Chevaleyre;Pablo E. Castillo

  • Endocannabinoid-Mediated Long-Term Plasticity Requires cAMP/PKA Signaling and RIM1α

    Vivien Chevaleyre;Boris D. Heifets;Pascal S. Kaeser;Thomas C. Südhof

  • Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death

    Kyung Min Noh;Hidenori Yokota;Toshihiro Mashiko;Pablo E. Castillo

Frequent Co-Authors

Roger A. Nicoll
Roger A. Nicoll University of California, San Francisco
Francisco R. Morales
Francisco R. Morales University of the Republic
Michael H. Chase
Michael H. Chase University of California, Los Angeles
Robert C. Malenka
Robert C. Malenka Stanford University
Joseph D. Buxbaum
Joseph D. Buxbaum Icahn School of Medicine at Mount Sinai
Patrick R. Hof
Patrick R. Hof Icahn School of Medicine at Mount Sinai
Mark G. Baxter
Mark G. Baxter Icahn School of Medicine at Mount Sinai
R. Suzanne Zukin
R. Suzanne Zukin Albert Einstein College of Medicine
Olivier J. Manzoni
Olivier J. Manzoni Aix-Marseille University
Kamran Khodakhah
Kamran Khodakhah Albert Einstein College of Medicine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Pablo E. Castillo

Trending Scientists

Recently Published Articles