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Genetics

D-Index
89
Citations
37689
World Ranking
1107
National Ranking
7

Overview

Xueling Sim is a researcher affiliated with the National University of Singapore. Their work is primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. The scientist's subfields of expertise include Genetics, Molecular Biology, Physiology, Endocrinology, Diabetes and Metabolism, and Epidemiology.

Their research focuses on various topics including Genetic Associations and Epidemiology, Genomics and Rare Diseases, Liver Disease Diagnosis and Treatment, Diet and Metabolism Studies, BRCA Gene Mutations in Cancer, Diabetes, Cardiovascular Risks, and Lipoproteins, as well as Metabolomics and Mass Spectrometry Studies.

Xueling Sim has contributed to numerous publications, with recent notable papers including:

  • The trans-ancestral genomic architecture of glycemic traits (2021, Nature Genetics)
  • A saturated map of common genetic variants associated with human height (2022, Nature)
  • Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020, Nature Genetics)
  • Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes (2022, JAMA Oncology)
  • Genetics in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference (2022, Kidney International)

The scientist frequently publishes in venues such as UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Nature Genetics, Nature Communications, and The Journal of Clinical Endocrinology & Metabolism.

Collaborations are a notable aspect of their career, with frequent co-authors including Rob M. van Dam, E Shyong Tai, Jin Fang Chai, Ching-Yu Cheng, and Jianjun Liu.

Best Publications

  • Biological, clinical and population relevance of 95 loci for blood lipids

    Tanya M. Teslovich;Kiran Musunuru;Albert V. Smith;Andrew C. Edmondson

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.

    Anubha Mahajan;Daniel Taliun;Matthias Thurner;Neil R. Robertson

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Christian Fuchsberger;Jason A. Flannick;Jason A. Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Mary F. Feitosa;Aldi T. Kraja;Daniel I. Chasman;Yun J. Sung

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

  • Seven new loci associated with age-related macular degeneration

    Lars G. Fritsche;Lars G. Fritsche;Wei Chen;Wei Chen;Matthew Schu;Brian L. Yaspan

  • The trans-ancestral genomic architecture of glycemic traits

    Ji Chen;Ji Chen;Cassandra N. Spracklen;Cassandra N. Spracklen;Gaëlle Marenne;Gaëlle Marenne;Arushi Varshney

  • Genome-Wide Association Study of Retinopathy in Individuals Without Diabetes

    Richard A. Jensen;Xueling Sim;Xiaohui Li;Mary Frances Cotch

  • Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

    Yoon Shin Cho;Chien Hsiun Chen;Chien Hsiun Chen;Cheng Hu;Jirong Long

  • Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

    Norihiro Kato;Fumihiko Takeuchi;Yasuharu Tabara;Tanika N. Kelly

  • Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

    Jaspal S Kooner;Danish Saleheen;Xueling Sim;Joban Sehmi;Joban Sehmi

  • Exome-wide association study of plasma lipids in > 300,000 individuals

    Dajiang J Liu;Gina M Peloso;Gina M Peloso;Haojie Yu;Adam S Butterworth;Adam S Butterworth

  • Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

    Z Dastani;Hivert M-F.;Hivert M-F.;N Timpson;Perry Jrb.;Perry Jrb.

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

    Elaine T. Lim;Peter Würtz;Peter Würtz;Peter Würtz;Aki S. Havulinna;Priit Palta;Priit Palta

  • The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

    Georg B. Ehret;Georg B. Ehret;Teresa Ferreira;Daniel I. Chasman;Anne U. Jackson

  • Meta-analysis identifies common variants associated with body mass index in east Asians

    Wanqing Wen;Yoon Shin Cho;Wei Zheng;Rajkumar Dorajoo;Rajkumar Dorajoo

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Jason Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

Frequent Co-Authors

Tien Yin Wong
Tien Yin Wong Tsinghua University
Jianjun Liu
Jianjun Liu Genome Institute of Singapore
John C. Chambers
John C. Chambers Guy's and St Thomas' NHS Foundation Trust
Jaspal S. Kooner
Jaspal S. Kooner Imperial College London
Weihua Zhang
Weihua Zhang Imperial College London
Andrew P. Morris
Andrew P. Morris University of Liverpool
Chiea Chuen Khor
Chiea Chuen Khor Agency for Science, Technology and Research
Yik Ying Teo
Yik Ying Teo National University of Singapore
Ching-Yu Cheng
Ching-Yu Cheng National University of Singapore

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Related Online Degrees & Career Pathways

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