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Masahiro Hirama

Masahiro Hirama

D-Index & Metrics

Chemistry

D-Index
63
Citations
12492
World Ranking
8541
National Ranking
578

Overview

Masahiro Hirama is affiliated with Tohoku University in Japan. Their research primarily focuses on environmental science and neuroscience, with a notable emphasis on environmental chemistry and the endocrine and autonomic systems.

The main topics explored in Hirama's work include marine toxins and detection methods, neuroscience of respiration and sleep, nicotinic acetylcholine receptors study, protist diversity and phylogeny, microbial community ecology and physiology, marine and coastal ecosystems, and forensic toxicology and drug analysis.

Hirama has contributed frequently to several scientific journals. The most common publication venues are:

  • Toxicon
  • Harmful Algae
  • Analytical Chemistry
  • Ecotoxicology and Environmental Safety
  • Food Chemistry

The following are selected recent publications by Hirama, detailing the title, year, and venue:

  • Addressing the Analytical Challenges for the Detection of Ciguatoxins Using an Electrochemical Biosensor, 2020, Analytical Chemistry
  • Rapid detection of ciguatoxins in Gambierdiscus and Fukuyoa with immunosensing tools, 2020, Ecotoxicology and Environmental Safety
  • A smartphone-controlled amperometric immunosensor for the detection of Pacific ciguatoxins in fish, 2021, Food Chemistry
  • Evaluation of relative potency of calibrated ciguatoxin congeners by near-infrared fluorescent receptor binding and neuroblastoma cell-based assays, 2023, Toxicon
  • Sensitive Detection of Ciguatoxins Using a Neuroblastoma Cell-Based Assay with Voltage-Gated Potassium Channel Inhibitors, 2024, Toxins

Masahiro Hirama has collaborated extensively with several coauthors. Among the most frequent collaborators are:

  • Takeshi Tsumuraya
  • Mònica Campàs
  • Jorge Diogène
  • Sandra Leonardo
  • Greta Gaiani

The scope of Hirama's work reveals an interdisciplinary approach encompassing molecular biology and ecological perspectives within environmental science and neuroscience. The research covers both fundamental and applied aspects of toxin detection and neurobiological processes.

Best Publications

  • ASYMMETRIC MICHAEL ADDITION OF MALONATE ANIONS TO PROCHIRAL ACCEPTORS CATALYZED BY L-PROLINE RUBIDIUM SALT

    Masahiko Yamaguchi;Tai Shiraishi;Masahiro Hirama

  • Total synthesis of ciguatoxin CTX3C

    Masahiro Hirama;Tohru Oishi;Hisatoshi Uehara;Masayuki Inoue

  • A Catalytic Enantioselective Michael Addition of a Simple Malonate to Prochiral α,β‐Unsaturated Ketoses and Aldehydes

    Masahiko Yamaguchi;Tai Shiraishi;Masahiro Hirama

  • TOTAL SYNTHESIS OF 6-DEOXYERYTHRONOLIDE B

    S. Masamune;M. Hirama;S. Mori;S. A. Ali

  • The Absolute Configuration of Ciguatoxin

    Masayuki Satake;Akio Morohashi;Hiroki Oguri;Tohru Oishi

  • Asymmetric Michael addition of nitroalkanes to prochiral acceptors catalyzed by proline rubidium salts

    Masahiko Yamaguchi;Yoshihiro Igarashi;Ravinder S Reddy;Tai Shiraishi

  • Practical total synthesis of ciguatoxin CTX3C by improved protective group strategy.

    Masayuki Inoue;Hisatoshi Uehara;Megumi Maruyama;Masahiro Hirama

  • First- and second-generation total synthesis of ciguatoxin CTX3C

    Masayuki Inoue;Keisuke Miyazaki;Hisatoshi Uehara;Megumi Maruyama

  • Asymmetric Baylis-Hillman reactions using chiral 2,3-disubstituted 1,4-diazabicyclo[2.2.2]octanes catalysts under high pressure conditions

    Tohru Oishi;Hiroki Oguri;Masahiro Hirama

  • Inhibition of brevetoxin binding to the voltage-gated sodium channel by gambierol and gambieric acid-A.

    Masayuki Inoue;Masahiro Hirama;Masayuki Satake;Kiminori Sugiyama

  • A chiral total synthesis of compactin

    Masahiro Hirama;Mitsuko Uei

  • The 10-membered ring analogs of neocarzinostatin chromophore: design, synthesis and mode of decomposition

    Masahiro Hirama;Kenshu Fujiwara;Kuniyoshi Shigematu;Yoshimasa Fukazawa

  • CATALYTIC ASYMMETRIC MICHAEL ADDITION OF NITROALKANE TO ENONE AND ENAL

    Masahiko Yamaguchi;Tai Shiraishi;Yoshihiro Igarashi;Masahiro Hirama

  • Total Synthesis of Merrilactone A

    Masayuki Inoue;Takaaki Sato;Masahiro Hirama

  • Synthesis and Characterization of Nine-Membered Cyclic Enediynes, Models of the C-1027 and Kedarcidin Chromophores: Equilibration with a p-Benzyne Biradical and Kinetic Stabilization

    Kyo-ichiro Iida;Masahiro Hirama

  • Total synthesis of ciguatoxin and 51-hydroxyCTX3C

    Masayuki Inoue;Keisuke Miyazaki;Yuuki Ishihara;Atsushi Tatami

  • Carbamate-mediated functionalization of unsaturated alcohols. 3. Intramolecular Michael addition of O-carbamates to .alpha.,.beta.-unsaturated esters. A new diastereoselective amination in an acyclic system

    Masahiro Hirama;Takeo Shigemoto;Yutaka Yamazaki;Sho Ito

  • Synthetic Study of Kedarcidin Chromophore: Revised Structure

    Shinji Kawata;Shukuko Ashizawa;Masahiro Hirama

  • Highly Enantioselective Dihydroxylation of Trans-Disubstituted and Monosubstituted Olefins

    Tohru Oishi;Masahiro Hirama

  • Evolution of a Practical Total Synthesis of Ciguatoxin CTX3C

    Masayuki Inoue;Masahiro Hirama

Frequent Co-Authors

Masahiko Yamaguchi
Masahiko Yamaguchi Tohoku University
Masayuki Inoue
Masayuki Inoue University of Tokyo
Toshiyuki Tanaka
Toshiyuki Tanaka Hyogo University of Health Sciences
Yoshikazu Tanaka
Yoshikazu Tanaka Tohoku University
Luis M. Botana
Luis M. Botana University of Santiago de Compostela
Mercedes R. Vieytes
Mercedes R. Vieytes University of Santiago de Compostela
Takeshi Yasumoto
Takeshi Yasumoto Tohoku University
Nobuyuki Harada
Nobuyuki Harada Tohoku University
Samuel J. Danishefsky
Samuel J. Danishefsky Columbia University
Koji Kano
Koji Kano Doshisha University

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