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Brett D. Lindenbach

Brett D. Lindenbach

D-Index & Metrics

Microbiology

D-Index
48
Citations
18815
World Ranking
4622
National Ranking
1784

Overview

Brett D. Lindenbach is affiliated with Yale University in the United States. Their research primarily focuses on the field of Medicine, with a specialization in Infectious Diseases, Epidemiology, Public Health, Environmental and Occupational Health, Molecular Biology, and Computational Theory and Mathematics.

Their work covers several main topics, including SARS-CoV-2 and COVID-19 Research, Mosquito-borne diseases and control, CRISPR and Genetic Engineering, Viral Infections and Vectors, COVID-19 Clinical Research Studies, Computational Drug Discovery Methods, and Hepatitis C virus research.

Frequent co-authors in their publications include:

  • Craig B. Wilen
  • Mia Madel Alfajaro
  • Laura Abriola
  • Yulia V. Surovtseva
  • Anna Marie Pyle

Publication venues where Brett D. Lindenbach has commonly contributed are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • Journal of Biological Chemistry
  • Proceedings of the National Academy of Sciences
  • UNC Libraries

Notable recent papers authored or co-authored by Lindenbach include:

  • Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection, 2020, Cell
  • De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report, 2022, Nature Communications
  • Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations, 2021, ACS Central Science
  • Restriction of SARS-CoV-2 replication by targeting programmed −1 ribosomal frameshifting, 2021, Proceedings of the National Academy of Sciences
  • Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Complete Replication of Hepatitis C Virus in Cell Culture

    Brett D. Lindenbach;Brett D. Lindenbach;Brett D. Lindenbach;Matthew J. Evans;Matthew J. Evans;Matthew J. Evans;Andrew J. Syder;Andrew J. Syder;Andrew J. Syder;Benno Wölk;Benno Wölk;Benno Wölk

  • Identification of microRNAs of the herpesvirus family

    Sébastien Pfeffer;Alain Sewer;Mariana Lagos-Quintana;Robert Sheridan

  • Unravelling hepatitis C virus replication from genome to function

    Brett D. Lindenbach;Charles M. Rice

  • Molecular biology of flaviviruses.

    Brett D Lindenbach;Charles M Rice

  • The viruses and their replication

    B. D. Lindenbach

  • Cellular cofactors affecting hepatitis C virus infection and replication

    Glenn Randall;Maryline Panis;Jacob D. Cooper;Timothy L. Tellinghuisen

  • Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

    Brett D. Lindenbach;Philip Meuleman;Alexander Ploss;Thomas Vanwolleghem

  • Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.

    Jin Wei;Mia Madel Alfajaro;Peter C. DeWeirdt;Ruth E. Hanna

  • Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry

    Donna M. Tscherne;Christopher T. Jones;Matthew J. Evans;Brett D. Lindenbach

  • Processing in the hepatitis C virus E2-NS2 region : identification of p7 and two distinct E2-specific products with different C termini

    C Lin;B D Lindenbach;B M Prágai;D W McCourt

  • Structural Insights into RNA Recognition by RIG-I

    Dahai Luo;Steve C. Ding;Adriana Vela;Andrew Kohlway

  • The ins and outs of hepatitis C virus entry and assembly.

    Brett D. Lindenbach;Charles M. Rice

  • trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replication.

    Brett D. Lindenbach;Charles M. Rice

  • De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report

    Unknown

  • Genetic Interaction of Flavivirus Nonstructural Proteins NS1 and NS4A as a Determinant of Replicase Function

    Brett D. Lindenbach;Charles M. Rice

  • Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection.

    Laura J. Yockey;Luis Varela;Tasfia Rakib;William Khoury-Hanold

  • Insertion of Green Fluorescent Protein into Nonstructural Protein 5A Allows Direct Visualization of Functional Hepatitis C Virus Replication Complexes

    Darius Moradpour;Darius Moradpour;Matthew J. Evans;Rainer Gosert;Zhenghong Yuan

  • Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus.

    David B. Kushner;Brett D. Lindenbach;Valery Z. Grdzelishvili;Amine O. Noueiry

  • Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

    Marco Onorati;Zhen Li;Fuchen Liu;André M.M. Sousa

  • Noncytopathic Sindbis virus RNA vectors for heterologous gene expression

    Eugene V. Agapov;Ilya Frolov;Brett D. Lindenbach;Béla M. Prágai

  • A stable full-length yellow fever virus cDNA clone and the role of conserved RNA elements in flavivirus replication.

    Peter J. Bredenbeek;Engbert A. Kooi;Brett Lindenbach;Nicolette Huijkman

Frequent Co-Authors

Charles M. Rice
Charles M. Rice Rockefeller University
Anna Marie Pyle
Anna Marie Pyle Yale University
Jane A. McKeating
Jane A. McKeating University of Oxford
Akiko Iwasaki
Akiko Iwasaki Yale University
Darius Moradpour
Darius Moradpour University of Lausanne
Ralf Bartenschlager
Ralf Bartenschlager Heidelberg University
Yves Jacob
Yves Jacob Institut Pasteur
Craig B. Wilen
Craig B. Wilen Yale University
Alexander Ploss
Alexander Ploss Princeton University

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