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Hans-Peter Lenhof

Hans-Peter Lenhof

D-Index & Metrics

Computer Science

D-Index
40
Citations
6526
World Ranking
9328
National Ranking
459

Overview

Hans-Peter Lenhof is affiliated with Saarland University in Germany and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Cancer Research, Computational Theory and Mathematics, Oncology, and Artificial Intelligence.

Their research encompasses several key topics, including:

  • Computational Drug Discovery Methods
  • Bioinformatics and Genomic Networks
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • RNA Research and Splicing
  • RNA Interference and Gene Delivery

Among the recent publications attributed to Hans-Peter Lenhof are:

  • miRTargetLink 2.0-interactive miRNA target gene and target pathway networks (2021, Nucleic Acids Research)
  • Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients (2020, JAMA Oncology)
  • GeneTrail 3: advanced high-throughput enrichment analysis (2020, Nucleic Acids Research)
  • Validation of human microRNA target pathways enables evaluation of target prediction tools (2020, Nucleic Acids Research)
  • Wrinkle in the plan: miR-34a-5p impacts chemokine signaling by modulating CXCL10/CXCL11/CXCR3-axis in CD4+, CD8+ T cells, and M1 macrophages (2020, Journal for ImmunoTherapy of Cancer)

Frequent co-authors of Hans-Peter Lenhof are:

  • Tim Kehl
  • Lea Eckhart
  • Eckart Meese
  • Andreas Keller
  • Kerstin Lenhof

Lenhof's work has appeared mostly in venues such as:

  • Nucleic Acids Research
  • Scientific Reports
  • Briefings in Bioinformatics
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • An estimate of the total number of true human miRNAs.

    Alles J;Fehlmann T;Fischer U;Backes C

  • GeneTrail—advanced gene set enrichment analysis

    Christina Backes;Andreas Keller;Jan Kuentzer;Benny Kneissl

  • A new Lamarckian genetic algorithm for flexible ligand‐receptor docking

    Jan Fuhrmann;Alexander Rurainski;Hans-Peter Lenhof;Dirk Neumann

  • An integer linear programming approach for finding deregulated subgraphs in regulatory networks

    Christina Backes;Alexander Rurainski;Gunnar W. Klau;Oliver Müller

  • miRPathDB 2.0: a novel release of the miRNA Pathway Dictionary Database.

    Tim Kehl;Fabian Kern;Christina Backes;Tobias Fehlmann

  • miRNAs in lung cancer - Studying complex fingerprints in patient's blood cells by microarray experiments

    Andreas Keller;Petra Leidinger;Anne Borries;Anke Wendschlag

  • q-gram based database searching using a suffix array (QUASAR)

    Stefan Burkhardt;Andreas Crauser;Paolo Ferragina;Hans-Peter Lenhof

  • miRTargetLink 2.0-interactive miRNA target gene and target pathway networks

    Fabian Kern;Ernesto Aparicio-Puerta;Yongping Li;Tobias Fehlmann

  • High-throughput miRNA profiling of human melanoma blood samples

    Petra Leidinger;Andreas Keller;Anne Borries;Jörg Reichrath

  • About miRNAs, miRNA seeds, target genes and target pathways.

    Tim Kehl;Christina Backes;Fabian Kern;Tobias Fehlmann

  • Stable serum miRNA profiles as potential tool for non-invasive lung cancer diagnosis.

    Andreas Keller;Petra Leidinger;Randi Elin Gislefoss;Aage Haugen

  • Multi-omics enrichment analysis using the GeneTrail2 web service

    Daniel Stöckel;Tim Kehl;Patrick Trampert;Lara Schneider

  • GraBCas: a bioinformatics tool for score-based prediction of Caspase- and Granzyme B-cleavage sites in protein sequences

    Christina Backes;Jan Kuentzer;Hans-Peter Lenhof;Nicole Comtesse

  • BALL - Rapid Software Prototyping in Computational Molecular Biology

    Oliver Kohlbacher;Hans-Peter Lenhof

  • EDISON-WMW: Exact Dynamic Programing Solution of the Wilcoxon-Mann-Whitney Test.

    Alexander Marx;Christina Backes;Eckart Meese;Hans-Peter Lenhof

  • Static and dynamic algorithms for k -point clustering problems

    Amitava Datta;Hans-Peter Lenhof;Christian Schwarz;Michiel Smid

  • miRPathDB: a new dictionary on microRNAs and target pathways.

    Christina Backes;Tim Kehl;Daniel Stöckel;Tobias Fehlmann

  • Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients.

    Tobias Fehlmann;Mustafa Kahraman;Nicole Ludwig;Christina Backes

  • Phylogenomics with paralogs

    Marc Hellmuth;Nicolas Wieseke;Marcus Lechner;Hans-Peter Lenhof

  • miRCarta: a central repository for collecting miRNA candidates

    Christina Backes;Tobias Fehlmann;Fabian Kern;Tim Kehl

  • A combinatorial approach to protein docking with flexible side chains.

    Ernst Althaus;Oliver Kohlbacher;Hans-Peter Lenhof;Peter Müller

  • GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments.

    Andreas Keller;Christina Backes;Maher Al-Awadhi;Andreas Gerasch

Frequent Co-Authors

Andreas Keller
Andreas Keller Saarland University
Eckart Meese
Eckart Meese Saarland University
Christina Backes
Christina Backes Saarland University
Oliver Kohlbacher
Oliver Kohlbacher University of Tübingen
Michiel Smid
Michiel Smid Carleton University
Michael Kaufmann
Michael Kaufmann University of Tübingen
Knut Reinert
Knut Reinert Freie Universität Berlin
Manfred Gessler
Manfred Gessler University of Würzburg
Martin Vingron
Martin Vingron Max Planck Society
Thomas Lengauer
Thomas Lengauer Max Planck Institute for Informatics

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