D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 56 Citations 13,895 192 World Ranking 9789 National Ranking 231

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

Peter J. van der Spek mostly deals with Genetics, Molecular biology, Gene expression profiling, Gene and Internal medicine. His Molecular biology research incorporates themes from Exome sequencing, Exome, Basic helix-loop-helix and Coronal suture. The concepts of his Gene expression profiling study are interwoven with issues in Survival rate, Regulation of gene expression, Chromosome, Comparative genomic hybridization and Cyclin D1.

His work investigates the relationship between Regulation of gene expression and topics such as Carcinoma that intersect with problems in Survival analysis and Bioinformatics. His biological study spans a wide range of topics, including Antiestrogen and Cancer research. His work on Cohort, Myocardial infarction and Endarterectomy as part of general Internal medicine study is frequently linked to Osteoblast, bridging the gap between disciplines.

His most cited work include:

  • Prognostically useful gene-expression profiles in acute myeloid leukemia. (1170 citations)
  • Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair (759 citations)
  • A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study (620 citations)

What are the main themes of his work throughout his whole career to date?

Peter J. van der Spek mainly focuses on Genetics, Gene, Pathology, Gene expression profiling and Gene expression. His Mutation, Genome, DNA microarray, Missense mutation and Craniosynostosis study are his primary interests in Genetics. His Gene research is multidisciplinary, relying on both Molecular biology and Cancer research.

Peter J. van der Spek combines subjects such as Breast cancer and Immunology with his study of Cancer research. The various areas that Peter J. van der Spek examines in his Gene expression profiling study include Internal medicine and Oncology. Peter J. van der Spek studies Internal medicine, namely Cohort.

He most often published in these fields:

  • Genetics (33.99%)
  • Gene (22.17%)
  • Pathology (12.81%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (11.82%)
  • Pathology (12.81%)
  • Gene (22.17%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Pathology, Gene, Genetics and Cancer research. His research integrates issues of Transcriptome, Nucleosome, Microcephaly, Regulator and Coronal suture in his study of Cell biology. His study in the fields of Carcinoma in situ, Vulva and Cerebral malformations under the domain of Pathology overlaps with other disciplines such as Vulvar Squamous Cell Carcinoma.

His study focuses on the intersection of Gene and fields such as Immune system with connections in the field of Lung cancer and Adenocarcinoma. Genetics and Endocrinology are commonly linked in his work. His work in the fields of Neovascularization overlaps with other areas such as Stromal cell-derived factor 1.

Between 2018 and 2021, his most popular works were:

  • De Novo Missense Substitutions in the Gene Encoding CDK8, a Regulator of the Mediator Complex, Cause a Syndromic Developmental Disorder. (24 citations)
  • Loss of SMPD4 Causes a Developmental Disorder Characterized by Microcephaly and Congenital Arthrogryposis (16 citations)
  • Molecular Binding Mechanism and Pharmacology Comparative Analysis of Noscapine for Repurposing against SARS-CoV-2 Protease. (14 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

His primary scientific interests are in Cell biology, Genetics, Transcription factor, Microcephaly and Rational design. His Cell biology study combines topics from a wide range of disciplines, such as Regulator and Thioredoxin. His study in Genetics concentrates on Transcription, Allele, Gene, Trichothiodystrophy and Compound heterozygosity.

His Transcription factor research integrates issues from Transcription factor II H, Craniosynostosis, Coronal suture, General transcription factor and Nucleosome. His studies in Microcephaly integrate themes in fields like Multipolar spindles, Centrosome, Lissencephaly and Ciliogenesis. Peter J. van der Spek performs multidisciplinary studies into Rational design and Fecal bacteriotherapy in his work.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Prognostically useful gene-expression profiles in acute myeloid leukemia.

Peter J.M. Valk;Roel G.W. Verhaak;M. Antoinette Beijen;Claudia A.J. Erpelinck.
The New England Journal of Medicine (2004)

1474 Citations

Xeroderma Pigmentosum Group C Protein Complex Is the Initiator of Global Genome Nucleotide Excision Repair

Kaoru Sugasawa;Jessica M.Y Ng;Chikahide Masutani;Shigenori Iwai.
Molecular Cell (1998)

1095 Citations

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

Monique L Den Boer;Marjon van Slegtenhorst;Renée X De Menezes;Renée X De Menezes;Meyling H Cheok.
Lancet Oncology (2009)

956 Citations

Gene expression-based classification of non-small cell lung carcinomas and survival prediction.

Jun Hou;Joachim Aerts;Bianca den Hamer;Wilfred van IJcken.
PLOS ONE (2010)

696 Citations

Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology

Lonneke A M Gravendeel;Mathilde C M Kouwenhoven;Olivier Gevaert;Johan J de Rooi.
Cancer Research (2009)

599 Citations

Composition of Carotid Atherosclerotic Plaque Is Associated With Cardiovascular Outcome A Prognostic Study

Willem E. Hellings;Wouter Peeters;Frans L. Moll;Sebastiaan R.D. Piers.
Circulation (2010)

482 Citations

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

Joseph Borg;Petros Papadopoulos;Marianthi Georgitsi;Laura Gutiérrez.
Nature Genetics (2010)

429 Citations

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling

Willem A. Dik;Karin Pike-Overzet;Floor Weerkamp;Dick de Ridder;Dick de Ridder.
Journal of Experimental Medicine (2005)

417 Citations

The Three Subfamilies of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors (LGR): Identification of LGR6 and LGR7 and the Signaling Mechanism for LGR7

Sheau Yu Hsu;Masataka Kudo;Thomas Chen;Koji Nakabayashi.
Molecular Endocrinology (2000)

392 Citations

Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines

Antoinette Hollestelle;Jord H. A. Nagel;Marcel Smid;Suzanne Lam.
Breast Cancer Research and Treatment (2010)

309 Citations

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