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Brian David Dynlacht

Brian David Dynlacht

D-Index & Metrics

Molecular Biology

D-Index
77
Citations
33356
World Ranking
1094
National Ranking
567

Overview

Brian David Dynlacht is affiliated with New York University in the United States and has a research focus within Biochemistry, Genetics, and Molecular Biology. Their scholarly output includes significant work in molecular biology, cell biology, genetics, cancer research, and pathology and forensic medicine.

The scientist's research spans several main topics, including:

  • Genetic and Kidney Cyst Diseases
  • Microtubule and mitosis dynamics
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • Ubiquitin and proteasome pathways
  • Epigenetics and DNA Methylation
  • RNA Research and Splicing

Brian David Dynlacht has published extensively in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Death and Differentiation
  • Epigenetics & Chromatin
  • Cell Reports
  • Nature Communications

Recent papers authored by or involving Brian David Dynlacht include:

  • "Apoptotic cell death in disease-Current understanding of the NCCD 2023" (2023), published in Cell Death and Differentiation
  • "Cilium induction triggers differentiation of glioma stem cells" (2021), published in Cell Reports
  • "Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology" (2020), published in Nature Communications
  • "Regulators of tubulin polyglutamylation control nuclear shape and cilium disassembly by balancing microtubule and actin assembly" (2021), published in Cell Research
  • "MMP-2 is a novel histone H3 N-terminal protease necessary for myogenic gene activation" (2021), published in Epigenetics & Chromatin

Frequent collaborators include:

  • Mikito Owa
  • Irma Sánchez
  • Alessandro Magli
  • Rita C. R. Perlingeiro
  • Aristotelis Tsirigos

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Inhibition of cyclin-dependent kinases by p21.

    J W Harper;S J Elledge;K Keyomarsi;B Dynlacht

  • E2F integrates cell cycle progression with DNA repair, replication, and G2/M checkpoints

    Bing Ren;Hieu Cam;Yasuhiko Takahashi;Thomas Volkert

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • XBP1 Controls Diverse Cell Type- and Condition-Specific Transcriptional Regulatory Networks

    Diego Acosta-Alvear;Yiming Zhou;Alexandre Blais;Mary Tsikitis

  • Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

    Brian David Dynlacht;Timothy Hoey;Robert Tjian

  • Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.

    Raphael Margueron;Guohong Li;Kavitha Sarma;Alexandre Blais

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

    Yasuhiko Takahashi;Joseph B. Rayman;Brian David Dynlacht

  • Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators.

    Timothy Hoey;Robert O.J. Weinzierl;Grace Gill;Jin-Long Chen

  • Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition.

    James Koh;Greg H. Enders;Brian David Dynlacht;Ed Harlow

  • Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation.

    K. Helin;Chin-Lee Wu;A. R. Fattaey;J. A. Lees

  • Cdk-activating kinase complex is a component of human transcription factor TFIIH

    Ramin Shiekhattar;Fred Mermelstein;Robert P. Fisher;Ronny Drapkin

  • An initial blueprint for myogenic differentiation

    Alexandre Blais;Mary Tsikitis;Diego Acosta-Alvear;Roded Sharan

  • Differential regulation of E2F transactivation by cyclin/cdk2 complexes.

    B D Dynlacht;O Flores;J A Lees;E Harlow

  • Cep97 and CP110 suppress a cilia assembly program.

    Alexander Spektor;William Y. Tsang;David Khoo;Brian David Dynlacht

  • Cyclin-binding motifs are essential for the function of p21CIP1.

    Junjie Chen;Partha Saha;Sally Kornbluth;Brian D. Dynlacht

  • Emerging roles for E2F: Beyond the G1/S transition and DNA replication

    Hugh Cam;Brian David Dynlacht

  • CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells.

    Zhihong Chen;Vahan B. Indjeian;Michael McManus;Leyu Wang

  • E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

    Joseph B. Rayman;Yasuhiko Takahashi;Vahan B. Indjeian;Jan-Hermen Dannenberg

Frequent Co-Authors

Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Yuval Kluger
Yuval Kluger Yale University
Gerry Melino
Gerry Melino University of Rome Tor Vergata
Robert Tjian
Robert Tjian University of California, Berkeley
Carmen Garrido
Carmen Garrido University of Burgundy
Christopher N. Bowman
Christopher N. Bowman University of Colorado Boulder
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Ed Harlow
Ed Harlow Harvard University
Catherine Brenner
Catherine Brenner Université Paris Cité
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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