Toshiro Okazaki

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  8488
  Citations

• Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation.

  T Okazaki;R M Bell;Y A Hannun

  855
  Citations

• Caspases are Activated in a Branched Protease Cascade and Control Distinct Downstream Processes in Fas-induced Apoptosis

  Hirokazu Hirata;Atsushi Takahashi;Susumu Kobayashi;Shin Yonehara

  666
  Citations

• Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

  T. Okazaki;A. Bielawska;R.M. Bell;Y.A. Hannun

  641
  Citations

• Fractalkine in Vascular Biology. From Basic Research to Clinical Disease

  Hisanori Umehara;Eda T. Bloom;Toshiro Okazaki;Yutaka Nagano

  430
  Citations

• CX3C-Chemokine, Fractalkine-Enhanced Adhesion of THP-1 Cells to Endothelial Cells Through Integrin-Dependent and -Independent Mechanisms

  Seiji Goda;Toshio Imai;Osamu Yoshie;Osamu Yoneda

  310
  Citations

• Characteristics and partial purification of a novel cytosolic, magnesium-independent, neutral sphingomyelinase activated in the early signal transduction of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.

  T Okazaki;A Bielawska;N Domae;R M Bell

  299
  Citations

• Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  287
  Citations

• Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells.

  Shohei Yamaoka;Michihiko Miyaji;Toshiyuki Kitano;Hisanori Umehara

  282
  Citations

• Requirement of AP-1 for Ceramide-induced Apoptosis in Human Leukemia HL-60 Cells

  Hirofumi Sawai;Toshiro Okazaki;Hirotaka Yamamoto;Hakuro Okano

  262
  Citations

• The role of sphingomyelin and sphingomyelin synthases in cell death, proliferation and migration—from cell and animal models to human disorders

  Makoto Taniguchi;Toshiro Okazaki

  234
  Citations

• Ceramide-induced Translocation of Protein Kinase C-δ and -ϵ to the Cytosol IMPLICATIONS IN APOPTOSIS

  Hirofumi Sawai;Toshiro Okazaki;Toshiro Okazaki;Yasushi Takeda;Masaro Tashima

  232
  Citations

• Astroglial expression of ceramide in Alzheimer's disease brains: a role during neuronal apoptosis.

  H. Satoi;H. Tomimoto;R. Ohtani;T. Kitano

  220
  Citations

• Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes.

  Susumu Mitsutake;Kota Zama;Hazuki Yokota;Tetsuya Yoshida

  210
  Citations

• Role of membrane sphingomyelin and ceramide in platform formation for Fas-mediated apoptosis

  Michihiko Miyaji;Michihiko Miyaji;Zhe-Xiong Jin;Zhe-Xiong Jin;Shohei Yamaoka;Ryuichi Amakawa

  209
  Citations

• Fractalkine and vascular injury

  Hisanori Umehara;EdaT Bloom;Toshiro Okazaki;Naochika Domae

  209
  Citations

• Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice

  Masato Yano;Ken Watanabe;Tadashi Yamamoto;Kazutaka Ikeda

  195
  Citations

• Ceramide Generation in Nitric Oxide-induced Apoptosis ACTIVATION OF MAGNESIUM-DEPENDENT NEUTRAL SPHINGOMYELINASE VIA CASPASE-3

  Yasushi Takeda;Masaro Tashima;Atsushi Takahashi;Takashi Uchiyama

  185
  Citations

• Characterization of zebrafish caspase-3 and induction of apoptosis through ceramide generation in fish fathead minnow tailbud cells and zebrafish embryo

  Takeshi Yabu;Shuji Kishi;Toshiro Okazaki;Michiaki Yamashita

  182
  Citations

• Transcriptional regulation of protein kinase C by 1,25-dihydroxyvitamin D3 in HL-60 cells.

  L M Obeid;T Okazaki;L A Karolak;Y A Hannun

  181
  Citations