World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
82
Citations
21492
World Ranking
3141
National Ranking
1044

Overview

Guocan Yu is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Materials Science. Their work explores subfields including Molecular Biology, Biomedical Engineering, Immunology, Materials Chemistry, and Biomaterials.

The scientist's research focuses on several key topics: nanoplatforms for cancer theranostics, RNA interference and gene delivery, supramolecular chemistry and complexes, immunotherapy and immune responses, nanoparticle-based drug delivery, luminescence and fluorescent materials, and supramolecular self-assembly in materials.

Guocan Yu has contributed to multiple recent papers in high-impact venues, such as:

  • Supramolecular cancer nanotheranostics, 2021, Chemical Society Reviews
  • Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis, 2020, Nature Communications
  • Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines, 2020, Proceedings of the National Academy of Sciences
  • A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer, 2020, Science Advances
  • Endogenous Labile Iron Pool-Mediated Free Radical Generation for Cancer Chemodynamic Therapy, 2020, Journal of the American Chemical Society

The scientist frequently publishes in leading journals including Angewandte Chemie International Edition, Angewandte Chemie, Journal of the American Chemical Society, Advanced Materials, and Nature Communications.

Guocan Yu collaborates regularly with several coauthors, including Shaolong Qi, Xiaoyuan Chen, Feihe Huang, Xinyang Yu, and Lang Rao, maintaining ongoing joint research efforts.

Best Publications

  • Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy.

    Li-Sen Lin;Tao Huang;Jibin Song;Xiang-Yu Ou

  • Supramolecular Amphiphiles Based on Host-Guest Molecular Recognition Motifs.

    Guocan Yu;Kecheng Jie;Feihe Huang

  • Characterization of supramolecular gels

    Guocan Yu;Xuzhou Yan;Chengyou Han;Feihe Huang

  • Supramolecular chemotherapy based on host–guest molecular recognition: a novel strategy in the battle against cancer with a bright future

    Jiong Zhou;Guocan Yu;Feihe Huang

  • Pillar[6]arene/Paraquat Molecular Recognition in Water: High Binding Strength, pH-Responsiveness, and Application in Controllable Self-Assembly, Controlled Release, and Treatment of Paraquat Poisoning

    Guocan Yu;Xiangyan Zhou;Zibin Zhang;Chengyou Han

  • Glucose-Responsive Sequential Generation of Hydrogen Peroxide and Nitric Oxide for Synergistic Cancer Starving-Like/Gas Therapy.

    Wenpei Fan;Wenpei Fan;Nan Lu;Peng Huang;Yi Liu

  • Pillar[6]arene-Based Photoresponsive Host–Guest Complexation

    Guocan Yu;Chengyou Han;Zibin Zhang;Jianzhuang Chen

  • A water-soluble pillar[6]arene: synthesis, host-guest chemistry, and its application in dispersion of multiwalled carbon nanotubes in water.

    Guocan Yu;Min Xue;Zibin Zhang;Jinying Li

  • Supramolecular cancer nanotheranostics

    Jiong Zhou;Lang Rao;Guocan Yu;Guocan Yu;Timothy R. Cook

  • Activatable Singlet Oxygen Generation from Lipid Hydroperoxide Nanoparticles for Cancer Therapy

    Zijian Zhou;Zijian Zhou;Jibin Song;Rui Tian;Rui Tian;Zhen Yang

  • Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis

    Lang Rao;Lei Wu;Zhida Liu;Rui Tian;Rui Tian

  • A Sugar-Functionalized Amphiphilic Pillar[5]arene: Synthesis, Self-Assembly in Water, and Application in Bacterial Cell Agglutination

    Guocan Yu;Yingjie Ma;Chengyou Han;Yong Yao

  • Tumor-Specific Drug Release and Reactive Oxygen Species Generation for Cancer Chemo/Chemodynamic Combination Therapy.

    Sheng Wang;Sheng Wang;Zhantong Wang;Guocan Yu;Zijian Zhou

  • Supramolecular Polymer-Based Nanomedicine: High Therapeutic Performance and Negligible Long-Term Immunotoxicity.

    Guocan Yu;Xinlian Zhao;Jiong Zhou;Zhengwei Mao

  • A solvent-driven molecular spring

    Zibin Zhang;Chengyou Han;Guocan Yu;Feihe Huang

  • Enhanced Antitumor Efficacy by a Cascade of Reactive Oxygen Species Generation and Drug Release.

    Sheng Wang;Sheng Wang;Guocan Yu;Zhantong Wang;Orit Jacobson

  • A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer

    Qianqian Ni;Qianqian Ni;Fuwu Zhang;Yijing Liu;Zhantong Wang

  • Highly Emissive Self-Assembled BODIPY-Platinum Supramolecular Triangles

    Jiong Zhou;Jiong Zhou;Yuzhen Zhang;Guocan Yu;Guocan Yu;Matthew R. Crawley

  • Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines

    Lang Rao;Shuai Xia;Wei Xu;Rui Tian

  • Polyrotaxane-based supramolecular theranostics

    Guocan Yu;Zhen Yang;Zhen Yang;Xiao Fu;Xiao Fu;Bryant C. Yung

  • Smart Nanovesicle-Mediated Immunogenic Cell Death through Tumor Microenvironment Modulation for Effective Photodynamic Immunotherapy

    Weijing Yang;Weijing Yang;Fuwu Zhang;Hongzhang Deng;Lisen Lin

  • Hierarchical Self-Assembly: Well-Defined Supramolecular Nanostructures and Metallohydrogels via Amphiphilic Discrete Organoplatinum(II) Metallacycles

    Xuzhou Yan;Xuzhou Yan;Shijun Li;Shijun Li;Timothy R. Cook;Xiaofan Ji

Frequent Co-Authors

Xiaoyuan Chen
Xiaoyuan Chen National University of Singapore
Feihe Huang
Feihe Huang Zhejiang University
Sheng Wang
Sheng Wang Tianjin University
Zijian Zhou
Zijian Zhou National Institutes of Health
Zhen Yang
Zhen Yang Fujian Normal University
Lisen Lin
Lisen Lin National Institutes of Health
Orit Jacobson
Orit Jacobson National Institutes of Health
Gang Niu
Gang Niu Xi'an Jiaotong University
Jibin Song
Jibin Song Nanyang Technological University
Yunlu Dai
Yunlu Dai University of Macau

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