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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
14849
World Ranking
14239
National Ranking
6004

Overview

Timothy P. Fleming is affiliated with St. Joseph's Hospital and Medical Center in the United States. Their research spans multiple disciplines within medicine and biochemistry, genetics, and molecular biology, with significant contributions in molecular biology, surgery, pulmonary and respiratory medicine, cancer research, and oncology.

Their work focuses on a variety of topics, including:

  • Extracellular vesicles in disease
  • Transplantation: Methods and Outcomes
  • Immunotherapy and Immune Responses
  • MicroRNA in disease regulation
  • Renal Transplantation Outcomes and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Fleming has published extensively, with notable recent papers including:

  • Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer-BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA Vaccines, 2021, The Journal of Immunology
  • Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis, 2023, Cell Reports Medicine
  • Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation, 2021, Genome Medicine
  • Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients, 2024, Genome Medicine
  • Low-dose IL-2 prevents murine chronic cardiac allograft rejection: Role for IL-2-induced T regulatory cells and exosomes with PD-L1 and CD73, 2022, American Journal of Transplantation

Their frequent coauthors include:

  • Ross M. Bremner
  • Sandhya Bansal
  • Thalachallour Mohanakumar
  • Michael A. Smith
  • Narendra V. Sankpal

Fleming's research has appeared frequently in the following publication venues:

  • The Journal of Heart and Lung Transplantation
  • Transplant Immunology
  • The Journal of Immunology
  • Genome Medicine
  • American Journal of Transplantation

Best Publications

  • Circulating tumor cells in patients with breast cancer dormancy

    Songdong Meng;Debasish Tripathy;Eugene P. Frenkel;Sanjay Shete

  • Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.

    Toru Miki;Donald P. Bottaro;Timothy P. Fleming;Cheryl L. Smith

  • Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

    Pier Paolo Di Fiore;Jacalyn H. Pierce;Timothy P. Fleming;Rachel Hazan

  • HER-2 gene amplification can be acquired as breast cancer progresses.

    Songdong Meng;Debasish Tripathy;Sanjay Shete;Raheela Ashfaq

  • Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop.

    Toru Miki;Timothy P. Fleming;Donald P. Bottaro;Jeffrey S. Rubin

  • PDGF induction of tyrosine phosphorylation of GTPase activating protein.

    Christopher J. Molloy;Donald P. Bottaro;Timothy P. Fleming;Mark S. Marshall

  • Amplification and/or Overexpression of Platelet-derived Growth Factor Receptors and Epidermal Growth Factor Receptor in Human Glial Tumors

    Fleming Tp;Saxena A;Clark Wc;Robertson Jt

  • Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer.

    Mark A. Watson;Timothy P. Fleming

  • Local Magnetohydrodynamical Models of Layered Accretion Disks

    Timothy Fleming;James M. Stone

  • Oncogene ect2 is related to regulators of small GTP-binding proteins

    Toru Miki;Cheryl L. Smith;Jason E. Long;Alessandra Eva

  • Local Magnetohydrodynamic Models of Layered Accretion Disks

    Timothy Fleming;James M. Stone

  • Autocrine interaction between TGF alpha and the EGF-receptor: quantitative requirements for induction of the malignant phenotype.

    E. Di Marco;J. H. Pierce;T. P. Fleming;M. H. Kraus

  • The Effect of Resistivity on the Nonlinear Stage of the Magnetorotational Instability in Accretion Disks

    Timothy P. Fleming;James M. Stone;James M. Stone;John F. Hawley

  • Signal Transduction through the EGF Receptor Transfected in IL-3--Dependent Hematopoietic Cells

    JH Pierce;M Ruggiero;TP Fleming;PP Di Fiore

  • Mammaglobin Expression in Primary, Metastatic, and Occult Breast Cancer

    Mark A. Watson;Suzanne Dintzis;Christopher M. Darrow;Lora E. Voss

  • MyoD induces growth arrest independent of differentiation in normal and transformed cells.

    Marco Crescenzi;Timothy P. Fleming;Andrew B. Lassar;Harold Weintraub

  • Propagation and Immortalization of Human Lens Epithelial Cells in Culture

    Usha P. Andley;Johng S. Rhim;Leo T. Chylack;Timothy P. Fleming

  • Isolation of Differentially Expressed Sequence Tags from Human Breast Cancer

    Mark A. Watson;Timothy P. Fleming

  • Keratinocyte Growth Factor: A Fibroblast Growth Factor Family Member with Unusual Target Cell Specificity

    Stuart A. Aaronson;Donald P. Bottaro;Toru Miki;Dina Ron

  • Differential Protective Activity of αA- and αB-crystallin in Lens Epithelial Cells

    Usha P. Andley;Zheng Song;Eric F. Wawrousek;Timothy P. Fleming

Frequent Co-Authors

Stuart A. Aaronson
Stuart A. Aaronson Icahn School of Medicine at Mount Sinai
William E. Gillanders
William E. Gillanders Washington University in St. Louis
Toru Miki
Toru Miki National Institutes of Health
T. Mohanakumar
T. Mohanakumar Washington University in St. Louis
Jacalyn H. Pierce
Jacalyn H. Pierce National Institutes of Health
Matthew J. Ellis
Matthew J. Ellis Baylor College of Medicine
Donald P. Bottaro
Donald P. Bottaro National Institutes of Health
Ted H. Hansen
Ted H. Hansen Washington University in St. Louis
Eric F. Wawrousek
Eric F. Wawrousek National Institutes of Health
Elaine R. Mardis
Elaine R. Mardis The Ohio State University

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