D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 41 Citations 6,660 99 World Ranking 3252 National Ranking 289

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Genetics

His primary areas of investigation include Scrapie, Virology, Immunology, Infectivity and Molecular biology. Richard I. Carp specializes in Scrapie, namely PrPSc Proteins. His work deals with themes such as Epitope, Antibody, Proteinase K and Incubation period, which intersect with Virology.

As a part of the same scientific family, Richard I. Carp mostly works in the field of Epitope, focusing on Monoclonal antibody and, on occasion, Humoral immunity and Heterologous. His Infectivity research is multidisciplinary, relying on both In vitro, Pathogenesis, Spleen, Cell type and In vivo. His study in Molecular biology is interdisciplinary in nature, drawing from both Genetics, Gene expression, Open reading frame, Single-nucleotide polymorphism and Methionine.

His most cited work include:

  • Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins. (722 citations)
  • Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides (261 citations)
  • Immunization delays the onset of prion disease in mice (200 citations)

What are the main themes of his work throughout his whole career to date?

Richard I. Carp focuses on Scrapie, Virology, Pathology, Molecular biology and Incubation period. His Scrapie study is concerned with Internal medicine in general. His work is dedicated to discovering how Virology, Genotype are connected with Allele and other disciplines.

Richard I. Carp has included themes like Cerebral cortex, Hippocampus and Blood–brain barrier in his Pathology study. His Molecular biology research includes elements of Monoclonal antibody, Western blot, Gene expression and Astrocyte. In his research, Cell is intimately related to Cell culture, which falls under the overarching field of Virus.

He most often published in these fields:

  • Scrapie (52.38%)
  • Virology (40.95%)
  • Pathology (19.05%)

What were the highlights of his more recent work (between 2006-2016)?

  • Scrapie (52.38%)
  • Molecular biology (18.10%)
  • Virology (40.95%)

In recent papers he was focusing on the following fields of study:

Richard I. Carp spends much of his time researching Scrapie, Molecular biology, Virology, Genetics and PRNP. His Scrapie study integrates concerns from other disciplines, such as In vitro, Biochemistry, Neurodegeneration, Messenger RNA and Cell biology. His Messenger RNA study which covers Pathology that intersects with Hippocampus.

The Molecular biology study combines topics in areas such as Cell culture, Neuroglia, Receptor and Antibody, Monoclonal antibody. As part of the same scientific family, Richard I. Carp usually focuses on Monoclonal antibody, concentrating on Epitope and intersecting with Innate immune system and TLR9. His work on Transmission is typically connected to Oral route as part of general Virology study, connecting several disciplines of science.

Between 2006 and 2016, his most popular works were:

  • Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis. (55 citations)
  • Involvement of peptidylarginine deiminase-mediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease (52 citations)
  • Accelerated Prion Disease Pathogenesis in Toll-Like Receptor 4 Signaling-Mutant Mice (43 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Genetics

His primary scientific interests are in Immunology, Molecular biology, Scrapie, Citrullination and Cell biology. His biological study spans a wide range of topics, including Neuroglia, Antibody, Monoclonal antibody and Pathology. His Monoclonal antibody research includes themes of Epitope and CpG Oligodeoxynucleotide.

His Scrapie research incorporates themes from Cerebral cortex, Pathogen and Hippocampus. His Immune system research is multidisciplinary, incorporating elements of TLR9 and Virology. His studies deal with areas such as Epidemiology, Central nervous system disease and Human genome as well as Virology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins.

R J Kascsak;R Rubenstein;P A Merz;M Tonna-DeMasi.
Journal of Virology (1987)

1133 Citations

Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

Claudio Soto;Richard J Kascsak;Gabriela P Saborío;Pierre Aucouturier.
The Lancet (2000)

382 Citations

Scrapie-associated prion protein accumulates in astrocytes during scrapie infection

J. F. Diedrich;P. E. Bendheim;Y. S. Kim;R. I. Carp.
Proceedings of the National Academy of Sciences of the United States of America (1991)

255 Citations

Copper chelation delays the onset of prion disease.

Einar M. Sigurdsson;David R. Brown;Muhammad A. Alim;Henrieta Scholtzova.
Journal of Biological Chemistry (2003)

230 Citations

Immunization delays the onset of prion disease in mice

Einar M. Sigurdsson;David R. Brown;Maki Daniels;Richard J. Kascsak.
American Journal of Pathology (2002)

224 Citations

Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie

Pierre Aucouturier;Frédéric Geissmann;Diane Damotte;Gabriela P. Saborio.
Journal of Clinical Investigation (2001)

215 Citations

Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains.

R J Kascsak;R Rubenstein;P A Merz;R I Carp.
Journal of Virology (1986)

185 Citations

Anti-prion antibodies for prophylaxis following prion exposure in mice.

Einar M. Sigurdsson;Man Sun Sy;Ruliang Li;Henrieta Scholtzova.
Neuroscience Letters (2003)

175 Citations

Isolation of a cDNA clone encoding the leader peptide of prion protein and expression of the homologous gene in various tissues

Nikolaos K. Robakis;Prithvi R. Sawh;Gloria C. Wolfe;Richard Rubenstein.
Proceedings of the National Academy of Sciences of the United States of America (1986)

173 Citations

Mitochondrial dysfunction induced by oxidative stress in the brains of hamsters infected with the 263 K scrapie agent.

Seung-Il Choi;Won-Kyu Ju;Eun-Kyoung Choi;Jin Kim.
Acta Neuropathologica (1998)

158 Citations

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