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Medicine

D-Index
121
Citations
98383
World Ranking
3523
National Ranking
1939

Research.com Recognitions

  • 2008 - Sedgwick Memorial Medal, American Public Health Association
  • 2008 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology
  • 2004 - Metlife Foundation Award for Medical Research in Alzheimer's Disease

Overview

William E. Klunk is affiliated with the University of Pittsburgh in the United States. Their research primarily falls within the field of Medicine, with a significant focus on Psychiatry and Mental Health, Physiology, Radiology, Nuclear Medicine and Imaging, Public Health, Environmental and Occupational Health, and Cognitive Neuroscience.

The topics central to their work include:

  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Down syndrome and intellectual disability research
  • Functional Brain Connectivity Studies
  • Frailty in Older Adults
  • Medical Imaging Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications

Frequent publication venues for their work are:

  • Alzheimer's & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer's & Dementia Diagnosis Assessment & Disease Monitoring
  • Neurobiology of Aging
  • Journal of Nuclear Medicine

William E. Klunk has collaborated extensively with several researchers, including:

  • Dana Tudorascu
  • Ann D. Cohen
  • Tharick A. Pascoal
  • Victor L. Villemagne
  • Pedro Rosa-Neto

Recent notable publications include:

  • Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease, 2023, Nature Medicine
  • Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid, 2022, Nature
  • Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum, 2022, JAMA Neurology
  • Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer's disease, 2022, Molecular Psychiatry
  • The Alzheimer's Biomarker Consortium-Down Syndrome: Rationale and methodology, 2020, Alzheimer's & Dementia Diagnosis Assessment & Disease Monitoring

William E. Klunk's research efforts have been recognized with awards such as:

  • Sedgwick Memorial Medal, American Public Health Association, 2008
  • Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology, 2008
  • Metlife Foundation Award for Medical Research in Alzheimer's Disease, 2004

Best Publications

  • The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

    Guy M. McKhann;Guy M. McKhann;David S. Knopman;Howard Chertkow;Bradley T. Hyman

  • Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B.

    William E. Klunk;Henry Engler;Agneta Nordberg;Yanming Wang

  • Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease

    Randall J. Bateman;Chengjie Xiong;Tammie L.S. Benzinger;Anne M. Fagan

  • The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

    G.M. McKhann;D.S. Knopman;H. Chertkow;B.T. Hyman

  • Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory

    Randy L. Buckner;Abraham Z. Snyder;Benjamin J. Shannon;Gina LaRossa

  • Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

    Stephen Salloway;Reisa Sperling;Nick C. Fox;Kaj Blennow

  • Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

    Willemijn J. Jansen;Rik Ossenkoppele;Dirk L. Knol;Betty M. Tijms

  • Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

    Anne M. Fagan;Mark A. Mintun;Robert H. Mach;Sang-Yoon Lee

  • Imaging beta-amyloid burden in aging and dementia.

    Christopher C Rowe;Steven Ng;Uwe Ackermann;Sylvia Gong

  • Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly

    Howard Jay Aizenstein;Robert D. Nebes;Judith A. Saxton;Julie C. Price

  • [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease.

    M. A. Mintun;G. N. LaRossa;Y. I. Sheline;C. S. Dence

  • SYNTHESIS AND EVALUATION OF 11C-LABELED 6-SUBSTITUTED 2-ARYLBENZOTHIAZOLES AS AMYLOID IMAGING AGENTS

    Chester A. Mathis;Yanming Wang;Daniel P. Holt;Guo Feng Huang

  • Post-mortem Correlates of in Vivo PiB-PET Amyloid Imaging in a Typical Case of Alzheimer's Disease

    Milos D. Ikonomovic;William E. Klunk;Eric E. Abrahamson;Chester A. Mathis

  • 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment.

    Clifford R. Jack;Val J. Lowe;Matthew L. Senjem;Stephen D. Weigand

  • C-11-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

    Juha O Rinne;David J Brooks;Martin N Rossor;Nick C Fox

  • Longitudinal Assessment of Aβ and Cognition in Aging and Alzheimer Disease

    Victor L Villemagne;Kerryn E Pike;Gaël Chételat;Kathryn A Ellis

  • Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

    Eric M. Reiman;Kewei Chen;Xiaofen Liu;Daniel Bandy

  • Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease.

    Kerryn Elizabeth Pike;Gregory Raymond Savage;Victor L Villemagne;Steven Ng

  • Brain Imaging in Alzheimer Disease

    Keith A. Johnson;Nick C. Fox;Reisa A. Sperling;William E. Klunk

  • Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease'

    Peter Davies;Judith Resnick;Burton Resnick;Sid Gilman

Frequent Co-Authors

Chester A. Mathis
Chester A. Mathis University of Pittsburgh
Julie C. Price
Julie C. Price Harvard University
Steven T. DeKosky
Steven T. DeKosky University of Florida
Oscar L. Lopez
Oscar L. Lopez University of Pittsburgh
Beth E. Snitz
Beth E. Snitz University of Pittsburgh
Howard J. Aizenstein
Howard J. Aizenstein University of Pittsburgh
Milos D. Ikonomovic
Milos D. Ikonomovic University of Pittsburgh
Jay W. Pettegrew
Jay W. Pettegrew University of Pittsburgh
Benjamin L. Handen
Benjamin L. Handen University of Pittsburgh
John C. Morris
John C. Morris Washington University in St. Louis

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