D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 107 Citations 64,827 462 World Ranking 3589 National Ranking 2040

Research.com Recognitions

Awards & Achievements

2008 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology

2008 - Sedgwick Memorial Medal, American Public Health Association

2004 - Metlife Foundation Award for Medical Research in Alzheimer's Disease

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Alzheimer's disease
  • Disease

The scientist’s investigation covers issues in Alzheimer's disease, Pathology, Pittsburgh compound B, Amyloid and Dementia. His work deals with themes such as Apolipoprotein E, Alzheimer's disease biomarkers and Central nervous system disease, which intersect with Alzheimer's disease. The concepts of his Pathology study are interwoven with issues in Precuneus and Pediatrics.

His studies deal with areas such as Positron emission tomography, Nuclear medicine, Magnetic resonance imaging, Cognitive disorder and Brain mapping as well as Pittsburgh compound B. His Amyloid research is multidisciplinary, incorporating elements of In vitro, Biochemistry, Presenilin, Genetically modified mouse and In vivo. His Dementia research incorporates themes from Psychiatry, Clinical trial and Neuroscience.

His most cited work include:

  • The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease (9237 citations)
  • Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. (3385 citations)
  • Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease (2062 citations)

What are the main themes of his work throughout his whole career to date?

William E. Klunk mostly deals with Pathology, Amyloid, Alzheimer's disease, Pittsburgh compound B and Internal medicine. The various areas that he examines in his Pathology study include Preclinical imaging and In vivo. His Amyloid study integrates concerns from other disciplines, such as Biopsy, Biochemistry, Amyloid beta and Amyloidosis.

His Alzheimer's disease study deals with Dementia intersecting with Biomarker. His research investigates the link between Pittsburgh compound B and topics such as Positron emission tomography that cross with problems in Magnetic resonance imaging. William E. Klunk combines subjects such as Endocrinology, Oncology, Cardiology, Cognition and Down syndrome with his study of Internal medicine.

He most often published in these fields:

  • Pathology (36.97%)
  • Amyloid (31.52%)
  • Alzheimer's disease (24.85%)

What were the highlights of his more recent work (between 2018-2021)?

  • Down syndrome (8.08%)
  • Disease (21.62%)
  • Internal medicine (21.82%)

In recent papers he was focusing on the following fields of study:

William E. Klunk spends much of his time researching Down syndrome, Disease, Internal medicine, Amyloid and Pittsburgh compound B. His Down syndrome research is multidisciplinary, incorporating perspectives in White matter, Neurodegeneration, Neuroimaging, Dementia and Episodic memory. In Dementia, William E. Klunk works on issues like Neuropsychology, which are connected to Clinical Dementia Rating.

His Internal medicine study incorporates themes from Endocrinology and Oncology. William E. Klunk studied Amyloid and Neuroscience that intersect with Alzheimer's disease. His Pittsburgh compound B research focuses on subjects like Positron emission tomography, which are linked to Nuclear magnetic resonance.

Between 2018 and 2021, his most popular works were:

  • Multisite study of the relationships between antemortem [11C]PIB‐PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology (49 citations)
  • Distinct cytokine profiles in human brains resilient to Alzheimer's pathology. (31 citations)
  • Fluid and PET biomarkers for amyloid pathology in Alzheimer's disease. (25 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Disease
  • Alzheimer's disease

His main research concerns Down syndrome, Disease, Pittsburgh compound B, Amyloid and Internal medicine. His Disease research is within the category of Pathology. His Pittsburgh compound B research includes elements of Positron emission tomography, Precuneus, Multivariate statistics and Genome-wide association study.

William E. Klunk interconnects Apolipoprotein E and Dementia in the investigation of issues within Amyloid. As a part of the same scientific family, William E. Klunk mostly works in the field of Internal medicine, focusing on Endocrinology and, on occasion, Pet imaging, Standardized uptake value, Repeated measures design and Genotype. The study incorporates disciplines such as Alzheimer's disease and Atrophy in addition to Neuropsychology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

Guy M. McKhann;Guy M. McKhann;David S. Knopman;Howard Chertkow;Bradley T. Hyman.
Alzheimers & Dementia (2011)

11517 Citations

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B.

William E. Klunk;Henry Engler;Agneta Nordberg;Yanming Wang.
Annals of Neurology (2004)

4803 Citations

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease

Randall J. Bateman;Chengjie Xiong;Tammie L.S. Benzinger;Anne M. Fagan.
The New England Journal of Medicine (2012)

3239 Citations

Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory

Randy L. Buckner;Abraham Z. Snyder;Benjamin J. Shannon;Gina LaRossa.
The Journal of Neuroscience (2005)

2144 Citations

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

Stephen Salloway;Reisa Sperling;Nick C. Fox;Kaj Blennow.
The New England Journal of Medicine (2014)

1735 Citations

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

Anne M. Fagan;Mark A. Mintun;Robert H. Mach;Sang-Yoon Lee.
Annals of Neurology (2006)

1382 Citations

Imaging beta-amyloid burden in aging and dementia.

Christopher C Rowe;Steven Ng;Uwe Ackermann;Sylvia Gong.
Neurology (2007)

1206 Citations

[11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease.

M. A. Mintun;G. N. LaRossa;Y. I. Sheline;C. S. Dence.
Neurology (2006)

1171 Citations

Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly

Howard Jay Aizenstein;Robert D. Nebes;Judith A. Saxton;Julie C. Price.
JAMA Neurology (2008)

1101 Citations

SYNTHESIS AND EVALUATION OF 11C-LABELED 6-SUBSTITUTED 2-ARYLBENZOTHIAZOLES AS AMYLOID IMAGING AGENTS

Chester A. Mathis;Yanming Wang;Daniel P. Holt;Guo Feng Huang.
Journal of Medicinal Chemistry (2003)

1095 Citations

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