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Microbiology

D-Index
43
Citations
7143
World Ranking
5255
National Ranking
131

Overview

Karin J. Metzner is affiliated with the University of Zurich in Switzerland. Their research expertise spans medicine and immunology and microbiology, with a particular focus on infectious diseases and virology. Their work notably addresses HIV research and treatment, including drug development, interventions, and HIV-related health complications.

The scientist has contributed extensively to several key areas of study, including:

  • HIV Research and Treatment
  • HIV/AIDS Research and Interventions
  • HIV/AIDS drug development and treatment
  • HIV-related health complications and treatments
  • Immune Cell Function and Interaction
  • Hepatitis C virus research
  • CRISPR and Genetic Engineering

Scientific publication venues where Karin J. Metzner has frequently published include:

  • The Journal of Infectious Diseases (16 publications)
  • Clinical Infectious Diseases (13 publications)
  • Open Forum Infectious Diseases (13 publications)
  • Viruses (8 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (8 publications)

Their recent published papers demonstrate a concentration on viral genetics, HIV epidemiology, and clinical impacts of antiretroviral therapy. Selected recent papers include:

  • Cohort Profile Update: The Swiss HIV Cohort Study (SHCS), 2021, International Journal of Epidemiology
  • V-pipe: a computational pipeline for assessing viral genetic diversity from high-throughput data, 2021, Bioinformatics
  • A highly virulent variant of HIV-1 circulating in the Netherlands, 2022, Science
  • Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV, 2022, Zurich Open Repository and Archive (University of Zurich)
  • Impact of Integrase Inhibitors on Cardiovascular Disease Events in People With Human Immunodeficiency Virus Starting Antiretroviral Therapy, 2023, Clinical Infectious Diseases

Karin J. Metzner collaborates regularly with several researchers, indicative of a broad and active research network. Frequent co-authors include:

  • Huldrych F. Günthard (122 co-authored publications)
  • Enos Bernasconi (105 co-authored publications)
  • Roger D. Kouyos (105 co-authored publications)
  • Matthias Cavassini (96 co-authored publications)
  • Dominique L. Braun (91 co-authored publications)

Their body of work contributes to a deeper understanding of infectious disease dynamics, with a particular emphasis on HIV epidemiology, antiviral resistance, and the immunological consequences of infection and treatment.

Best Publications

  • HIV suppression by interleukin-16.

    Michael Baier;Albrecht Werner;Norbert Bannert;Karin Metzner

  • Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis

    Jonathan Z. Li;Roger Paredes;Heather J. Ribaudo;Evguenia S. Svarovskaia

  • Minority Quasispecies of Drug-Resistant HIV-1 That Lead to Early Therapy Failure in Treatment-Naive and -Adherent Patients

    Karin J. Metzner;Stefano G. Giulieri;Stefanie A. Knoepfel;Pia Rauch

  • Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data

    Niko Beerenwinkel;Niko Beerenwinkel;Huldrych F. Günthard;Volker Roth;Karin J. Metzner

  • Effects of in vivo CD8(+) T cell depletion on virus replication in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine.

    Karin J. Metzner;Xia Jin;Fred V. Lee;Agegnehu Gettie

  • Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART.

    Nadine Bachmann;Chantal von Siebenthal;Valentina Vongrad;Teja Turk

  • Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions

    Karin J. Metzner;Karin J. Metzner;Sebastian Bonhoeffer;Marek Fischer;Rose Karanicolas

  • Detection of minor populations of drug-resistant HIV-1 in acute seroconverters.

    Karin J Metzner;Pia Rauch;Hauke Walter;Christoph Boesecke

  • Full-length haplotype reconstruction to infer the structure of heterogeneous virus populations

    Francesca Di Giallonardo;Armin Töpfer;Melanie Rey;Sandhya Prabhakaran

  • Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART: a multicohort European case–control study using centralized ultrasensitive 454 pyrosequencing

    Alessandro Cozzi-Lepri;Marc Noguera-Julian;Francesca Di Giallonardo;Rob Schuurman

  • Molecular cloning, expression and characterization of Pru a 1, the major cherry allergen

    S. Scheurer;K. Metzner;D. Haustein;S. Vieths

  • Blinded, Multicenter Comparison of Methods To Detect a Drug-Resistant Mutant of Human Immunodeficiency Virus Type 1 at Low Frequency

    Elias K. Halvas;Grace M. Aldrovandi;Peter Balfe;Ingrid A. Beck

  • Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo

    Satish K. Pillai;Mohamed Abdel-Mohsen;John Guatelli;Mark Skasko

  • Cohort Profile Update: The Swiss HIV Cohort Study (SHCS).

    Alexandra U Scherrer;Anna Traytel;Dominique L Braun;Alexandra Calmy

  • Profound Depletion of HIV-1 Transcription in Patients Initiating Antiretroviral Therapy during Acute Infection

    Adrian Schmid;Sara Gianella;Viktor von Wyl;Karin J. Metzner

  • Characterization of Human Immunodeficiency Virus Type 1 (HIV-1) Diversity and Tropism in 145 Patients With Primary HIV-1 Infection

    Philip Rieder;Beda Joos;Alexandra U. Scherrer;Herbert Kuster

  • Hepatitis B Virus Infection Is Associated With Impaired Immunological Recovery During Antiretroviral Therapy in the Swiss HIV Cohort Study

    Gilles Wandeler;Thomas Gsponer;Florian Bihl;Enos Bernasconi

  • V-pipe: a computational pipeline for assessing viral genetic diversity from high-throughput data.

    Susana Posada-Céspedes;Susana Posada-Céspedes;David Seifert;David Seifert;Ivan Topolsky;Ivan Topolsky;Kim Philipp Jablonski;Kim Philipp Jablonski

  • Treatment-Naive Individuals Are the Major Source of Transmitted HIV-1 Drug Resistance in Men Who Have Sex With Men in the Swiss HIV Cohort Study

    Sara M. Drescher;Viktor von Wyl;Wan-Lin Yang;Jürg Böni

  • Obesity Trends and Body Mass Index Changes After Starting Antiretroviral Treatment: The Swiss HIV Cohort Study

    Barbara Hasse;Martin Iff;Bruno Ledergerber;Alexandra Calmy

  • Efficient suppression of minority drug resistant HIV type 1 (HIV 1) variants present at primary HIV 1 infection by ritonavir boosted protease inhibitor-containing antiretroviral therapy.

    Karin J. Metzner;Karin J. Metzner;Pia Rauch;Viktor von Wyl;Christine Leemann

  • Assessing the Paradox Between Transmitted and Acquired HIV Type 1 Drug Resistance Mutations in the Swiss HIV Cohort Study From 1998 to 2012

    Wan-Lin Yang;Roger Kouyos;Alexandra U. Scherrer;Jürg Böni

Frequent Co-Authors

Huldrych F. Günthard
Huldrych F. Günthard University of Zurich
Jürg Böni
Jürg Böni University of Zurich
Roger D. Kouyos
Roger D. Kouyos University of Zurich
Matthias Cavassini
Matthias Cavassini University of Lausanne
Enos Bernasconi
Enos Bernasconi Universita della Svizzera Italiana
Sabine Yerly
Sabine Yerly University of Geneva
Thomas Klimkait
Thomas Klimkait University of Basel
Andri Rauch
Andri Rauch University of Bern
Rainer Weber
Rainer Weber University of Zurich

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Related Online Degrees & Career Pathways

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