Jacques Laval focuses on Biochemistry, DNA, Molecular biology, DNA glycosylase and AP site. As part of one scientific family, Jacques Laval deals mainly with the area of Biochemistry, narrowing it down to issues related to the DNA polymerase I, and often DNA polymerase and Polymerase. His DNA research is multidisciplinary, incorporating perspectives in Escherichia coli and Pyrimidine.
His Molecular biology research incorporates elements of DNA-formamidopyrimidine glycosylase and Oligonucleotide. The DNA-formamidopyrimidine glycosylase study which covers Formamidopyrimidine DNA glycosylase that intersects with MUTYH. In his research on the topic of DNA glycosylase, Thymine-DNA glycosylase and Uracil-DNA glycosylase is strongly related with Uracil.
His primary areas of investigation include Biochemistry, DNA, DNA glycosylase, Molecular biology and DNA repair. Biochemistry is a component of his AP site, Enzyme, DNA damage, DNA-formamidopyrimidine glycosylase and Cytosine studies. His DNA research includes themes of Stereochemistry, Guanine and Escherichia coli.
His DNA glycosylase research incorporates themes from Base excision repair, Nucleotide excision repair and Uracil. His studies deal with areas such as Plasmid, Mutagenesis, Mutant, Base pair and DNA polymerase as well as Molecular biology. His DNA repair research includes elements of Endogeny, Nitric oxide and Cell biology.
DNA, Biochemistry, DNA damage, DNA repair and DNA glycosylase are his primary areas of study. His DNA research is multidisciplinary, incorporating elements of Molecular biology, Gel electrophoresis, Phosphorus-32 and Escherichia coli. Jacques Laval specializes in Biochemistry, namely Oxidative stress.
His DNA damage research is multidisciplinary, relying on both Mutagen and Oligonucleotide. The concepts of his DNA repair study are interwoven with issues in Endogeny, Nitric oxide and Enzyme. His DNA glycosylase study integrates concerns from other disciplines, such as Base excision repair, Nucleotide excision repair and DNA polymerase.
Jacques Laval spends much of his time researching DNA repair, DNA, Biochemistry, Gel electrophoresis and DNA glycosylase. In DNA repair, Jacques Laval works on issues like DNA damage, which are connected to Single strand and Electrophoresis. He combines subjects such as Molecular biology, Cleavage and Recombinant DNA with his study of DNA.
His studies in Molecular biology integrate themes in fields like Cell cycle, Topoisomerase and Cell biology. His biological study spans a wide range of topics, including AP site, Biophysics, Endogeny and Purine. His research in DNA glycosylase intersects with topics in Base excision repair and Cytotoxic T cell.
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The multifaceted roles of nitric oxide in cancer.
D A Wink;Y Vodovotz;J Laval;F Laval.
Carcinogenesis (1998)
Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization.
Serge Boiteux;Ewa Gajewski;Jacques Laval;Miral Dizdaroglu.
Biochemistry (1992)
Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation
Betsy M. Sutherland;Paula V. Bennett;Olga Sidorkina;Jacques Laval.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Reaction Kinetics for Nitrosation of Cysteine and Glutathione in Aerobic Nitric Oxide Solutions at Neutral pH. Insights into the Fate and Physiological Effects of Intermediates Generated in the NO/O2 Reaction
David A. Wink;Raymond W. Nims;John F. Darbyshire;Danae Christodoulou.
Chemical Research in Toxicology (1994)
Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and overproduction of the protein.
S Boiteux;T R O'Connor;J Laval.
The EMBO Journal (1987)
Substrate specificity of the Escherichia coli endonuclease III : excision of thymine- and cytosine-derived lesions in DNA produced by radiation-generated free radicals
Miral Dizdaroglu;Jacques Laval;Serge Boiteux.
Biochemistry (1993)
Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases.
Murat Saparbaev;Jacques Laval.
Proceedings of the National Academy of Sciences of the United States of America (1994)
Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNA.
Murat Saparbaev;Karol Kleibl;Jacques Laval.
Nucleic Acids Research (1995)
Clustered damages and total lesions induced in DNA by ionizing radiation: oxidized bases and strand breaks.
Betsy M. Sutherland;Paula V. Bennett;Olga Sidorkina;Jacques Laval.
Biochemistry (2000)
3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase.
Murat Saparbaev;Jacques Laval.
Proceedings of the National Academy of Sciences of the United States of America (1998)
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