D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 50 Citations 9,492 94 World Ranking 13086 National Ranking 499

Overview

What is he best known for?

The fields of study he is best known for:

  • DNA
  • Enzyme
  • Gene

Jacques Laval focuses on Biochemistry, DNA, Molecular biology, DNA glycosylase and AP site. As part of one scientific family, Jacques Laval deals mainly with the area of Biochemistry, narrowing it down to issues related to the DNA polymerase I, and often DNA polymerase and Polymerase. His DNA research is multidisciplinary, incorporating perspectives in Escherichia coli and Pyrimidine.

His Molecular biology research incorporates elements of DNA-formamidopyrimidine glycosylase and Oligonucleotide. The DNA-formamidopyrimidine glycosylase study which covers Formamidopyrimidine DNA glycosylase that intersects with MUTYH. In his research on the topic of DNA glycosylase, Thymine-DNA glycosylase and Uracil-DNA glycosylase is strongly related with Uracil.

His most cited work include:

  • The multifaceted roles of nitric oxide in cancer. (588 citations)
  • Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization. (508 citations)
  • Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation (379 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Biochemistry, DNA, DNA glycosylase, Molecular biology and DNA repair. Biochemistry is a component of his AP site, Enzyme, DNA damage, DNA-formamidopyrimidine glycosylase and Cytosine studies. His DNA research includes themes of Stereochemistry, Guanine and Escherichia coli.

His DNA glycosylase research incorporates themes from Base excision repair, Nucleotide excision repair and Uracil. His studies deal with areas such as Plasmid, Mutagenesis, Mutant, Base pair and DNA polymerase as well as Molecular biology. His DNA repair research includes elements of Endogeny, Nitric oxide and Cell biology.

He most often published in these fields:

  • Biochemistry (70.59%)
  • DNA (69.61%)
  • DNA glycosylase (50.00%)

What were the highlights of his more recent work (between 2002-2007)?

  • DNA (69.61%)
  • Biochemistry (70.59%)
  • DNA damage (23.53%)

In recent papers he was focusing on the following fields of study:

DNA, Biochemistry, DNA damage, DNA repair and DNA glycosylase are his primary areas of study. His DNA research is multidisciplinary, incorporating elements of Molecular biology, Gel electrophoresis, Phosphorus-32 and Escherichia coli. Jacques Laval specializes in Biochemistry, namely Oxidative stress.

His DNA damage research is multidisciplinary, relying on both Mutagen and Oligonucleotide. The concepts of his DNA repair study are interwoven with issues in Endogeny, Nitric oxide and Enzyme. His DNA glycosylase study integrates concerns from other disciplines, such as Base excision repair, Nucleotide excision repair and DNA polymerase.

Between 2002 and 2007, his most popular works were:

  • Inhibition of poly(ADP-RIBOSE) polymerase (PARP) by nitric oxide and reactive nitrogen oxide species (71 citations)
  • A molecular beacon assay for measuring base excision repair activities. (69 citations)
  • Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis. (66 citations)

In his most recent research, the most cited papers focused on:

  • DNA
  • Enzyme
  • Gene

Jacques Laval spends much of his time researching DNA repair, DNA, Biochemistry, Gel electrophoresis and DNA glycosylase. In DNA repair, Jacques Laval works on issues like DNA damage, which are connected to Single strand and Electrophoresis. He combines subjects such as Molecular biology, Cleavage and Recombinant DNA with his study of DNA.

His studies in Molecular biology integrate themes in fields like Cell cycle, Topoisomerase and Cell biology. His biological study spans a wide range of topics, including AP site, Biophysics, Endogeny and Purine. His research in DNA glycosylase intersects with topics in Base excision repair and Cytotoxic T cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The multifaceted roles of nitric oxide in cancer.

D A Wink;Y Vodovotz;J Laval;F Laval.
Carcinogenesis (1998)

883 Citations

Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization.

Serge Boiteux;Ewa Gajewski;Jacques Laval;Miral Dizdaroglu.
Biochemistry (1992)

838 Citations

Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation

Betsy M. Sutherland;Paula V. Bennett;Olga Sidorkina;Jacques Laval.
Proceedings of the National Academy of Sciences of the United States of America (2000)

579 Citations

Reaction Kinetics for Nitrosation of Cysteine and Glutathione in Aerobic Nitric Oxide Solutions at Neutral pH. Insights into the Fate and Physiological Effects of Intermediates Generated in the NO/O2 Reaction

David A. Wink;Raymond W. Nims;John F. Darbyshire;Danae Christodoulou.
Chemical Research in Toxicology (1994)

391 Citations

Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and overproduction of the protein.

S Boiteux;T R O'Connor;J Laval.
The EMBO Journal (1987)

385 Citations

Substrate specificity of the Escherichia coli endonuclease III : excision of thymine- and cytosine-derived lesions in DNA produced by radiation-generated free radicals

Miral Dizdaroglu;Jacques Laval;Serge Boiteux.
Biochemistry (1993)

369 Citations

Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases.

Murat Saparbaev;Jacques Laval.
Proceedings of the National Academy of Sciences of the United States of America (1994)

327 Citations

Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNA.

Murat Saparbaev;Karol Kleibl;Jacques Laval.
Nucleic Acids Research (1995)

307 Citations

Clustered damages and total lesions induced in DNA by ionizing radiation: oxidized bases and strand breaks.

Betsy M. Sutherland;Paula V. Bennett;Olga Sidorkina;Jacques Laval.
Biochemistry (2000)

299 Citations

3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase.

Murat Saparbaev;Jacques Laval.
Proceedings of the National Academy of Sciences of the United States of America (1998)

233 Citations

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