Jacques Laval

Overview

Best Publications

• The multifaceted roles of nitric oxide in cancer.

  D A Wink;Y Vodovotz;J Laval;F Laval

  917
  Citations

• 8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.

  J Tchou;H Kasai;S Shibutani;M H Chung

  879
  Citations

• Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization.

  Serge Boiteux;Ewa Gajewski;Jacques Laval;Miral Dizdaroglu

  847
  Citations

• Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation

  Betsy M. Sutherland;Paula V. Bennett;Olga Sidorkina;Jacques Laval

  648
  Citations

• Reaction Kinetics for Nitrosation of Cysteine and Glutathione in Aerobic Nitric Oxide Solutions at Neutral pH. Insights into the Fate and Physiological Effects of Intermediates Generated in the NO/O2 Reaction

  David A. Wink;Raymond W. Nims;John F. Darbyshire;Danae Christodoulou

  401
  Citations

• Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and overproduction of the protein.

  S Boiteux;T R O'Connor;J Laval

  391
  Citations

• Substrate specificity of the Escherichia coli endonuclease III : excision of thymine- and cytosine-derived lesions in DNA produced by radiation-generated free radicals

  Miral Dizdaroglu;Jacques Laval;Serge Boiteux

  379
  Citations

• Excision of hypoxanthine from DNA containing dIMP residues by the Escherichia coli, yeast, rat, and human alkylpurine DNA glycosylases.

  Murat Saparbaev;Jacques Laval

  349
  Citations

• The type of DNA glycosylase determines the base excision repair pathway in mammalian cells.

  Paola Fortini;Eleonora Parlanti;Olga M. Sidorkina;Jacques Laval

  325
  Citations

• Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNA.

  Murat Saparbaev;Karol Kleibl;Jacques Laval

  314
  Citations

• Enzymology of the repair of free radicals-induced DNA damage.

  Laurent Gros;Murat K Saparbaev;Jacques Laval

  261
  Citations

• Clustered DNA Damages Induced by X Rays in Human Cells

  Betsy M. Sutherland;Paula V. Bennett;John C. Sutherland;John C. Sutherland;Jacques Laval

  244
  Citations

• The Fpg protein, a DNA repair enzyme, is inhibited by the biomediator nitric oxide in vitro and in vivo

  David A. Wink;Jacques Laval

  241
  Citations

• 3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase.

  Murat Saparbaev;Jacques Laval

  239
  Citations

• Clustered DNA damage, influence on damage excision by XRS5 nuclear extracts and Escherichia coli Nth and Fpg proteins.

  Marie-Hélène David-Cordonnier;Jacques Laval;Peter O'Neill

  229
  Citations

• Physical association of the 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase of Escherichia coli and an activity nicking DNA at apurinic/apyrimidinic sites.

  Timothy R. O'Connor;Jacques Laval

  216
  Citations

• Ring-opened 7-methylguanine residues in DNA are a block to in vitro DNA synthesis

  Timothy R. O'Connor;Sergio Boiteux;Jacques Laval

  199
  Citations

• Coding properties of poly(deoxycytidylic acid) templates containing uracil or apyrimidinic sites: in vitro modulation of mutagenesis by deoxyribonucleic acid repair enzymes.

  Serge Boiteux;Jacques Laval

  195
  Citations

• HU Protein of Escherichia coli Binds Specifically to DNA That Contains Single-strand Breaks or Gaps

  Bertrand Castaing;Charles Zelwer;Jacques Laval;Serge Boiteux

  195
  Citations

• Two enzymes are required for strand incision in repair of alkylated DNA

  Jacques Laval

  180
  Citations