Paul D. van Helden focuses on Tuberculosis, Mycobacterium tuberculosis, Immunology, Genetics and Drug resistance. His Tuberculosis research is multidisciplinary, incorporating perspectives in Virology, Internal medicine, Disease, Gene and Pharmacology. His Mycobacterium tuberculosis study incorporates themes from Restriction fragment length polymorphism, Genotype, Incidence and Microbiology.
The study incorporates disciplines such as Tuberculin, Multiplex and Genetic predisposition in addition to Immunology. His research in Genetics intersects with topics in Cape and Genetic admixture. His study in the field of Extensively drug-resistant tuberculosis is also linked to topics like Resistance mutation.
Paul D. van Helden spends much of his time researching Tuberculosis, Mycobacterium tuberculosis, Mycobacterium bovis, Immunology and Genetics. Paul D. van Helden combines subjects such as Transmission, Virology, Internal medicine, Disease and Drug resistance with his study of Tuberculosis. The various areas that Paul D. van Helden examines in his Drug resistance study include Drug and Intensive care medicine.
His Mycobacterium tuberculosis study integrates concerns from other disciplines, such as Restriction fragment length polymorphism, Genotype, Sputum and Microbiology. Paul D. van Helden focuses mostly in the field of Mycobacterium bovis, narrowing it down to topics relating to Wildlife and, in certain cases, Livestock. His biological study spans a wide range of topics, including Incidence and Haplotype.
His main research concerns Mycobacterium bovis, Tuberculosis, Virology, Bovine tuberculosis and Mycobacterium tuberculosis. His Mycobacterium bovis research includes themes of Zoology, Interferon gamma, Immune system, Microbiology and Interferon gamma release assay. He has researched Tuberculosis in several fields, including Disease, Public health and Environmental health.
His work carried out in the field of Virology brings together such families of science as Ceratotherium simum, Rhinoceros and Whole genome sequencing. His work investigates the relationship between Bovine tuberculosis and topics such as National park that intersect with problems in Captive elephants and Infection prevalence. His study in Mycobacterium tuberculosis is interdisciplinary in nature, drawing from both Incidence, Intensive care medicine, Incubation period, Recent transmission and Pediatrics.
The scientist’s investigation covers issues in Mycobacterium bovis, Tuberculosis, Interferon gamma, Virology and Interferon gamma release assay. His work deals with themes such as Transmission, Disease cluster, Infection prevalence and Immune system, which intersect with Mycobacterium bovis. The Tuberculosis study combines topics in areas such as Internal medicine and Cohort.
His Interferon gamma study combines topics from a wide range of disciplines, such as Biomarker, Whole blood and Interferon. Paul D. van Helden usually deals with Virology and limits it to topics linked to Serology and Phacochoerus, Tuberculin, Panthera and Free ranging. The study incorporates disciplines such as Pharmacokinetics, Wildlife, One Health, Public health and African elephant in addition to Mycobacterium tuberculosis.
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Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiology
Karine Brudey;Jeffrey R Driscoll;Leen Rigouts;Wolfgang M Prodinger.
BMC Microbiology (2006)
Rate of Reinfection Tuberculosis after Successful Treatment Is Higher than Rate of New Tuberculosis
Suzanne Verver;Robin M. Warren;Nulda Beyers;Madalene Richardson.
American Journal of Respiratory and Critical Care Medicine (2005)
The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Keertan Dheda;Tawanda Gumbo;Gary Maartens;Kelly E. Dooley.
The Lancet Respiratory Medicine (2017)
Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions
Nicolaas C Gey van Pittius;Samantha L Sampson;Hyeyoung Lee;Yeun Kim.
BMC Evolutionary Biology (2006)
Genetic susceptibility to tuberculosis in Africans: A genome-wide scan
Richard Bellamy;Nulda Beyers;Keith P. W. J. McAdam;Cyril Ruwende.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Mycobacterium bovis at the animal-human interface: a problem, or not?
Anita Luise Michel;Borna Müller;Paul David van Helden.
Veterinary Microbiology (2010)
Patients with active tuberculosis often have different strains in the same sputum specimen.
Robin M. Warren;Thomas C. Victor;Elizabeth M. Streicher;Madalene Richardson.
American Journal of Respiratory and Critical Care Medicine (2004)
Zoonotic Mycobacterium bovis - induced tuberculosis in humans.
Borna Müller;Salome Esther Dürr;Silvia Alonso;Jan Hattendorf.
Emerging Infectious Diseases (2013)
Novel Mycobacterium tuberculosis complex pathogen, M. mungi
Kathleen A. Alexander;Pete N. Laver;Anita Luise Michel;Mark C. Williams.
Emerging Infectious Diseases (2010)
Association between tuberculosis and a polymorphic NFκB binding site in the interferon γ gene
Manda Rossouw;Hendrik J Nel;Graham S Cooke;Paul D van Helden.
The Lancet (2003)
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