Rolf G. Boot

Overview

Best Publications

• Elevated globotriaosylsphingosine is a hallmark of Fabry disease

  Johannes M. Aerts;Johanna E. Groener;Sijmen Kuiper;Wilma E. Donker-Koopman

  799
  Citations

• Identification of a novel acidic mammalian chitinase distinct from chitotriosidase

  R.G. Boot;E.F.C. Blommaart;E. Swart;K. Ghauharali-Van der Vlugt

  608
  Citations

• Cloning of a cDNA Encoding Chitotriosidase, a Human Chitinase Produced by Macrophages

  R.G. Boot;G.H. Renkema;A. Strijland;A.J. van Zonneveld

  499
  Citations

• The human chitotriosidase gene - Nature of inherited enzyme deficiency

  R.G. Boot;G.H. Renkema;M. Verhoek;A. Strijland

  494
  Citations

• Chitotriosidase, a chitinase, and the 39‐kDa human cartilage glycoprotein, a chitin‐binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages

  G. H. Renkema;R. G. Boot;F. L. Au;W. E. Donker-Koopman

  467
  Citations

• Strong Induction of Members of the Chitinase Family of Proteins in Atherosclerosis Chitotriosidase and Human Cartilage gp-39 Expressed in Lesion Macrophages

  R. G. Boot;T. A. E. Van Achterberg;B. E. Van Aken;G. H. Renkema

  434
  Citations

• Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis.

  Leonie A Boven;Marjan Van Meurs;Marloes Van Zwam;Annet Wierenga-Wolf

  418
  Citations

• Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention.

  Rolf G. Boot;Marri Verhoek;Maaike de Fost;Carla E. M. Hollak

  415
  Citations

• Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins.

  G.H. Renkema;R.G. Boot;A.O. Muijsers;W.E. Donker-Koopman

  411
  Citations

• Glycosphingolipids—Nature, Function, and Pharmacological Modulation

  Tom Wennekes;Richard J. B. H. N. van den Berg;Rolf G. Boot;Gijsbert A. van der Marel

  367
  Citations

• Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity.

  Marco van Eijk;Cindy P. A. A. van Roomen;G. Herma Renkema;Anton P. Bussink

  358
  Citations

• Evolution of mammalian chitinase(-like) members of family 18 glycosyl hydrolases.

  Anton P. Bussink;Dave Speijer;Johannes M. F. G. Aerts;Rolf G. Boot

  342
  Citations

• Gaucher cells demonstrate a distinct macrophage phenotype and resemble alternatively activated macrophages.

  Leonie A. Boven;Marjan van Meurs;Rolf G. Boot;Atul Mehta

  342
  Citations

• Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response

  Nick Dekker;Laura van Dussen;Carla E. M. Hollak;Herman Overkleeft

  338
  Citations

• Structure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectins.

  Fabrizia Fusetti;Holger von Moeller;Douglas Houston;Henriëtte J. Rozeboom

  299
  Citations

• Ultrasensitive in situ visualization of active glucocerebrosidase molecules

  Martin D Witte;Wouter W Kallemeijn;Jan Aten;Kah-Yee Li

  292
  Citations

• Identification of the Non-lysosomal Glucosylceramidase as β-Glucosidase 2

  Rolf G. Boot;Marri Verhoek;Wilma Donker-Koopman;Anneke Strijland

  239
  Citations

• Transglycosidase Activity of Chitotriosidase IMPROVED ENZYMATIC ASSAY FOR THE HUMAN MACROPHAGE CHITINASE

  Begoña Aguilera;Karen Ghauharali-van der Vlugt;Mariette T. J. Helmond;Jos M. M. Out

  200
  Citations

• Synthesis, Sorting, and Processing into Distinct Isoforms of Human Macrophage Chitotriosidase

  G.H. Renkema;R.G. Boot;A. Strijland;W.E. Donker-Koopman

  198
  Citations

• Chapter Three Chapter Three Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention

  Erasmus Mc;Rolf G. Boot;Marri Verhoek;Maaike de Fost

  0
  Citations