World's Best Scientists 2026 revealed!
Douwe D. Breimer

Douwe D. Breimer

D-Index & Metrics

Medicine

D-Index
76
Citations
19325
World Ranking
18856
National Ranking
697

Research.com Recognitions

  • 1999 - Member of the National Academy of Medicine (NAM)
  • 1992 - Member of Academia Europaea
  • 1987 - Royal Netherlands Academy of Arts and Sciences

Overview

Douwe D. Breimer is affiliated with Leiden University in the Netherlands. Their research spans several fields including Medicine and Biochemistry, Genetics and Molecular Biology, with particular focus on the subfields of Physiology and Clinical Biochemistry.

The scientist's work concentrates on topics related to diet and metabolism studies as well as metabolism and genetic disorders. These areas have shaped the scope of their academic contributions.

Among the recent scholarly work attributed to Douwe D. Breimer is the paper titled "Professor Margareta Hammarlund-Udenaes - A Humble Scientist Shaping Modern Neuropharmacokinetics", published in 2022 in the journal Pharmaceutical Research.

Frequent collaborators in Breimer's research efforts include:

  • Irena Loryan
  • David E. Smith
  • Per Artursson
  • Yoshiharu Deguchi
  • Lennart Paalzow

Publication venues where this scientist has contributed frequently include:

  • Pharmaceutical Research

Throughout their career, Douwe D. Breimer has been recognized through various memberships in distinguished organizations, reflecting their academic standing. These awards include:

  • Member of the National Academy of Medicine (NAM) since 1999
  • Member of Academia Europaea since 1992
  • Member of the Royal Netherlands Academy of Arts and Sciences since 1987

Best Publications

  • The influence of cytokines on the integrity of the blood-brain barrier in vitro

    Helga E. de Vries;Margret C.M. Blom-Roosemalen;Marijke van Oosten;Albert G. de Boer

  • The Blood-Brain Barrier in Neuroinflammatory Diseases

    Helga E. de Vries;Johan Kuiper;Albertus G. de Boer;Theo J. C. Van Berkel

  • Penetration of Dexamethasone into Brain Glucocorticoid Targets Is Enhanced in mdr1A P-Glycoprotein Knockout Mice

    O. C. Meijer;E. C. M. de Lange;D. D. Breimer;A. G. de Boer

  • Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

    Jan Wijnholds;Elizabeth C.M. de Lange;George L. Scheffer;Dirk-Jan van den Berg

  • Establishment and functional characterization of an in vitro model of the blood-brain barrier, comprising a co-culture of brain capillary endothelial cells and astrocytes.

    Pieter Jaap Gaillard;Levina Helena Voorwinden;Jette Lyngholm Nielsen;Alexei Ivanov

  • Rectal drug administration: clinical pharmacokinetic considerations.

    A. G. de Boer;A. G. de Boer;F. Moolenaar;F. Moolenaar;L. G. J. de Leede;L. G. J. de Leede;D. D. Breimer;D. D. Breimer

  • Methodological issues in microdialysis sampling for pharmacokinetic studies.

    Elizabeth C.M. de Lange;A.G. de Boer;Douwe D. Breimer

  • Therapeutic drug monitoring in saliva.

    M. Danhof;D. D. Breimer

  • Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood–brain barrier

    de Lange Ec;Danhof M;de Boer Ag;Breimer Dd

  • Intestinal drug absorption enhancement: an overview

    E J van Hoogdalem;A G de Boer;D D Breimer

  • Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite α-hydroxymidazolam in healthy volunteers

    Jaap W Mandona;Bert Tuk;Alfred L van Steveninck;Douwe D Breimer

  • Rate of increase in the plasma concentration of nifedipine as a major determinant of its hemodynamic effects in humans

    C H Kleinbloesem;C H Kleinbloesem;P Van Brummelen;P Van Brummelen;M Danhof;M Danhof;H Faber;H Faber

  • DRUG ABSORPTION BY SUBLINGUAL AND RECTAL ROUTES

    A.G. De Boer;L.G.J. De Leede;D.D. Breimer

  • The role of glutathione conjugation in the mutagenicity of 1,2-dibromoethane

    P.J. van Bladeren;D.D. Breimer;G.M.T. Rotteveel-Smijs;R.A.W. De Jong

  • Variability in nifedipine pharmacokinetics and dynamics: A new oxidation polymorphism in man

    C.H. Kleinbloesem;P. van Brummelen;H. Faber;M. Danhof

  • The influence of phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin on glutathione s-transferase activity of rat liver cytosol

    A.J. Baars;M. Jansen;D.D. Breimer

  • Assay of antipyrine and its primary metabolites in plasma, saliva and urine by high-performance liquid chromatography and some preliminary results in man.

    M. Danhof;E. de Groot-van der Vis;D.D. Breimer

  • Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier.

    Pieter Jaap Gaillard;Inez Cornelia Johanna van der Sandt;Levina Helena Voorwinden;Dung Vu

  • Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood--brain barrier.

    Inez C. J. Van Der Sandt;Catherine M. P. Vos;Lobna Nabulsi;Margret C. M. Blom-Roosemalen

  • Interindividual variations in drug disposition. Clinical implications and methods of investigation.

    D. D. Breimer

Frequent Co-Authors

Meindert Danhof
Meindert Danhof Leiden University
P.J. van Bladeren
P.J. van Bladeren Nestlé (Switzerland)
Gerard J. Mulder
Gerard J. Mulder Leiden University
Johan Kuiper
Johan Kuiper Leiden University
Jo Hermans
Jo Hermans Leiden University
Adriaan P. IJzerman
Adriaan P. IJzerman Leiden University
Nico P. E. Vermeulen
Nico P. E. Vermeulen Vrije Universiteit Amsterdam
Theo J.C. Van Berkel
Theo J.C. Van Berkel Leiden University
Jan M. van Ree
Jan M. van Ree Utrecht University
Jeffrey R. Idle
Jeffrey R. Idle University of Bern

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring medicine in the USA opens diverse options besides traditional MD programs. Many prospective students consider non nursing bachelor's to msn online pathways. These programs allow individuals with non-nursing degrees to transition directly into advanced practice roles through accelerated online MSN degrees, saving both time and resources.

Some students look for accessible entry points into healthcare fields. There are easiest nursing programs to get into that offer less competitive admissions, making it easier for aspiring nurses to start or advance their careers.

Healthcare careers are not limited to patient care. Those interested in administration or remote work may benefit from medical coding and billing classes online with financial aid. These programs are flexible, accredited, and often come with financial support for eligible students.

Finally, if standardized exams are a concern, there are nursing schools that don't require teas or hesi exams for admission, simplifying the process even further.

Best Scientists Citing Douwe D. Breimer

Trending Scientists

Recently Published Articles