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Jing-Dong J. Han

Jing-Dong J. Han

D-Index & Metrics

Molecular Biology

D-Index
58
Citations
16742
World Ranking
2061
National Ranking
56

Overview

Jing-Dong J. Han is affiliated with Peking University in China and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with significant overlap in medicine. Their research spans various subfields, predominantly molecular biology, aging, physiology, cancer research, and genetics.

The main topics of Jing-Dong J. Han's work include:

  • Genetics, Aging, and Longevity in Model Organisms
  • Single-cell and spatial transcriptomics
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Genomics and Chromatin Dynamics
  • Gut microbiota and health

Their frequent co-authors comprise:

  • Jing Qu
  • Weiqi Zhang
  • Guang-Hui Liu
  • Wanyu Tao
  • Qiang Liu

Jing-Dong J. Han publishes regularly in several notable venues. The most common publication venues include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Science China Life Sciences
  • Cell Reports
  • Aging Cell
  • Nature Communications

Highlighted recent papers authored or co-authored by Jing-Dong J. Han include:

  • "Biomarkers of aging for the identification and evaluation of longevity interventions," 2023, Cell
  • "Individual variation of the SARS-CoV-2 receptor ACE2 gene expression and regulation," 2020, Aging Cell
  • "The landscape of aging," 2022, Science China Life Sciences
  • "Biomarkers of aging," 2023, Science China Life Sciences
  • "A human circulating immune cell landscape in aging and COVID-19," 2020, Protein & Cell

Jing-Dong J. Han's research portfolio reveals a focus on understanding mechanisms of aging and longevity, as well as intersections with molecular biology and immune system dynamics. Their work spans cellular and genetic levels, linking single-cell transcriptomics, epigenetics, and chromatin dynamics to broader physiological and pathological contexts.

Best Publications

  • A Map of the Interactome Network of the Metazoan C. elegans

    Siming Li;Christopher M. Armstrong;Nicolas Bertin;Hui Ge

  • Evidence for dynamically organized modularity in the yeast protein–protein interaction network

    Jing-Dong J. Han;Nicolas Bertin;Tong Hao;Debra S. Goldberg

  • Network modeling links breast cancer susceptibility and centrosome dysfunction.

    Miguel Angel Pujana;Jing Dong J Han;Lea M. Starita;Kristen N. Stevens

  • Annotation Transfer Between Genomes: Protein–Protein Interologs and Protein–DNA Regulogs

    Haiyuan Yu;Nicholas M. Luscombe;Hao Xin Lu;Xiaowei Zhu

  • Effect of sampling on topology predictions of protein-protein interaction networks.

    Jing-Dong J Han;Denis Dupuy;Nicolas Bertin;Michael E Cusick

  • Individual variation of the SARS-CoV-2 receptor ACE2 gene expression and regulation.

    Jiawei Chen;Quanlong Jiang;Xian Xia;Kangping Liu

  • The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity

    Bo Shan;Xiaoxia Wang;Ying Wu;Chi Xu

  • Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis

    Kristin C. Gunsalus;Hui Ge;Aaron J. Schetter;Debra S. Goldberg

  • Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels

    Andriana Margariti;Bernhard Winkler;Eirini Karamariti;Anna Zampetaki

  • Spatial transcriptomic analysis of cryosectioned tissue samples with Geo-seq

    Jun Chen;Shengbao Suo;Patrick Pl Tam;Jing-Dong J Han

  • BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes.

    Zhen Qi;Yehua Li;Bing Zhao;Chi Xu

  • Aging and Alzheimer's disease: Comparison and associations from molecular to system level.

    Xian Xia;Quanlong Jiang;Joseph McDermott;Jing-Dong J. Han

  • Histone Demethylase UTX-1 Regulates C. elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway

    Chunyu Jin;Chunyu Jin;Jing Li;Christopher D. Green;Xiaoming Yu;Xiaoming Yu

  • MCP-1 mediates TGF-β–induced angiogenesis by stimulating vascular smooth muscle cell migration

    Jing Ma;Qiang Wang;Teng Fei;Jing-Dong Jackie Han

  • MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4

    Qiang Wang;Zheng Huang;Huiling Xue;Chengcheng Jin

  • Spatial Transcriptome for the Molecular Annotation of Lineage Fates and Cell Identity in Mid-gastrula Mouse Embryo

    Guangdun Peng;Shengbao Suo;Jun Chen;Weiyang Chen

  • Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation.

    Clayton E. Friedman;Quan Nguyen;Samuel W. Lukowski;Abbigail Helfer

  • The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways.

    Qingqing Zhu;Qingqing Zhu;Lu Song;Guangdun Peng;Na Sun

  • A modular network model of aging.

    Huiling Xue;Bo Xian;Dong Dong;Kai Xia

  • Understanding biological functions through molecular networks

    Jing-Dong Jackie Han

Frequent Co-Authors

John R. Speakman
John R. Speakman University of Aberdeen
Patrick P.L. Tam
Patrick P.L. Tam University of Sydney
David Lusseau
David Lusseau Technical University of Denmark
Ye-Guang Chen
Ye-Guang Chen Tsinghua University
Luonan Chen
Luonan Chen Chinese Academy of Sciences
Daniel E. L. Promislow
Daniel E. L. Promislow University of Washington
Marc Vidal
Marc Vidal Harvard University
Philipp Khaitovich
Philipp Khaitovich Skolkovo Institute of Science and Technology
Joseph E. Powell
Joseph E. Powell Garvan Institute of Medical Research
Frederick P. Roth
Frederick P. Roth Lunenfeld-Tanenbaum Research Institute

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