D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 67 Citations 25,715 250 World Ranking 5110 National Ranking 113

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

Jan Koster spends much of his time researching Cancer research, Medulloblastoma, Cancer, Neuroblastoma and Gene expression profiling. His Cancer research research integrates issues from DNA methylation, Mutation, Immunology, Gene silencing and Epigenetics. The study incorporates disciplines such as Bioinformatics, Li–Fraumeni syndrome, Germline, Genomics and PTCH1 in addition to Medulloblastoma.

His Cancer research is multidisciplinary, incorporating perspectives in Microprocessor complex, DGCR8, Germline mutation and Human genetics. His studies deal with areas such as Molecular biology, Regulation of gene expression, Receptor and RNA interference as well as Neuroblastoma. His work in Gene expression profiling tackles topics such as Transcriptome which are related to areas like Cell, SNP, Retrospective cohort study, Meta-analysis and Adult Medulloblastoma.

His most cited work include:

  • Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. (1139 citations)
  • Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients (957 citations)
  • Dissecting the genomic complexity underlying medulloblastoma (621 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cancer research, Neuroblastoma, Cancer, Molecular biology and Cell biology. His research in Cancer research intersects with topics in Cellular differentiation, Gene expression profiling, Mutation, Carcinogenesis and Cell cycle. His Gene expression profiling research includes elements of Medulloblastoma and Metastasis.

Jan Koster has researched Neuroblastoma in several fields, including Regulation of gene expression, Gene silencing, Transcription factor and Apoptosis. His Cancer study combines topics from a wide range of disciplines, such as Transcriptome, Gene expression, Gene, Somatic cell and Immunology. His Molecular biology research is multidisciplinary, incorporating perspectives in Messenger RNA and N-Myc Proto-Oncogene Protein.

He most often published in these fields:

  • Cancer research (44.63%)
  • Neuroblastoma (36.78%)
  • Cancer (16.53%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cancer research (44.63%)
  • Neuroblastoma (36.78%)
  • Cancer (16.53%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cancer research, Neuroblastoma, Cancer, Cell biology and Transcription factor. His studies in Cancer research integrate themes in fields like Somatic cell, Carcinogenesis, Mutation, Transcriptome and In vivo. His study in Neuroblastoma is interdisciplinary in nature, drawing from both Lineage, Regulator, Gene silencing, Epigenetics and Mesenchymal stem cell.

His work in Cancer covers topics such as Gene which are related to areas like Prostate cancer and Oncology. His study looks at the relationship between Cell biology and fields such as Reprogramming, as well as how they intersect with chemical problems. His work carried out in the field of Transcription factor brings together such families of science as Chromatin, Promoter, Regulation of gene expression and Programmed cell death.

Between 2017 and 2021, his most popular works were:

  • The landscape of genomic alterations across childhood cancers (449 citations)
  • A biobank of patient-derived pediatric brain tumor models. (58 citations)
  • c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies (52 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

Jan Koster mostly deals with Cancer research, Neuroblastoma, Cancer, Cell biology and Gene expression profiling. His Cancer research research includes themes of Immunohistochemistry, Somatic cell, Phenotype, Transcriptome and In vivo. His research integrates issues of SNP, Oncology, Chromatin, Promoter and Locus in his study of Neuroblastoma.

His Cancer study combines topics in areas such as Biobank, DNA methylation, DNA, Frameshift mutation and Gene. His Cell biology research is multidisciplinary, incorporating elements of Stromal cell, Cellular differentiation, Transcription factor, Regulation of gene expression and Innate lymphoid cell. His Gene expression profiling research is multidisciplinary, relying on both TEAD4, Tyrosine kinase and Receptor tyrosine kinase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

Dominik Sturm;Hendrik Witt;Hendrik Witt;Volker Hovestadt;Dong Anh Khuong-Quang.
Cancer Cell (2012)

1657 Citations

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Marc van de Wetering;Hayley E. Francies;Joshua M. Francis;Joshua M. Francis;Gergana Bounova.
Cell (2015)

1589 Citations

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

Marcel Kool;Andrey Korshunov;Marc Remke;Marc Remke;David T.W. Jones.
Acta Neuropathologica (2012)

964 Citations

Dissecting the genomic complexity underlying medulloblastoma

David T. W. Jones;Natalie Jäger;Marcel Kool;Thomas Zichner.
Nature (2012)

850 Citations

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

Jan J. Molenaar;Jan Koster;Danny A. Zwijnenburg;Peter van Sluis.
Nature (2012)

843 Citations

The landscape of genomic alterations across childhood cancers

Susanne N. Gröbner;Barbara C. Worst;Joachim Weischenfeldt;Joachim Weischenfeldt;Ivo Buchhalter.
Nature (2018)

840 Citations

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

Kristian W. Pajtler;Kristian W. Pajtler;Hendrik Witt;Martin Sill;David T.W. Jones.
Cancer Cell (2015)

839 Citations

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

Tobias Rausch;David T.W. Jones;Marc Zapatka;Adrian M. Stütz.
Cell (2012)

811 Citations

Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

Marcel Kool;Jan Koster;Jens Bunt;Nancy E. Hasselt.
PLOS ONE (2008)

777 Citations

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

Javier Muñoz;Daniel E Stange;Arnout G Schepers;Marc van de Wetering.
The EMBO Journal (2012)

715 Citations

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