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D-Index
121
Citations
53144
World Ranking
3613
National Ranking
1994

Overview

Hiroyuki Shimada is a researcher affiliated with Stanford University in the United States. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields including Neurology, Molecular Biology, Cancer Research, Genetics, and Physiology.

The main research topics studied by Shimada include:

  • Neuroblastoma Research and Treatments
  • Cancer, Hypoxia, and Metabolism
  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Glioma Diagnosis and Treatment
  • Cancer therapeutics and mechanisms
  • Neurofibromatosis and Schwannoma Cases

Shimada's publication record features work in a variety of scientific journals. The frequent venues for publication include:

  • Journal of Clinical Oncology
  • Cancer Research
  • Pediatric Blood & Cancer
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Medicine

Selected recent papers authored or co-authored by Shimada include:

  • A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease, 2020, Nature Medicine
  • Revised Neuroblastoma Risk Classification System: A Report From the Children's Oncology Group, 2021, Journal of Clinical Oncology
  • Preclinical assessment of the efficacy and specificity of GD2-B7H3 SynNotch CAR-T in metastatic neuroblastoma, 2021, Nature Communications
  • Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results, 2023, Nature Medicine
  • Randomized Phase II Trial of MIBG Versus MIBG, Vincristine, and Irinotecan Versus MIBG and Vorinostat for Patients With Relapsed or Refractory Neuroblastoma: A Report From NANT Consortium, 2021, Journal of Clinical Oncology

Frequent collaborators include:

  • Bill Chiu
  • Julie R. Park
  • Naohiko Ikegaki
  • Arlene Naranjo
  • Susan L. Cohn

Best Publications

  • The International Neuroblastoma Pathology Classification (the Shimada system)

    Hiroyuki Shimada M.D.;Inge M. Ambros;Louis P. Dehner;Jun-ichi Hata

  • Histopathologic Prognostic Factors in Neuroblastic Tumors: Definition of Subtypes of Ganglioneuroblastoma and an Age-Linked Classification of Neuroblastomas

    Hiroyuki Shimada;Jane Chatten;William A. Newton;Nancy Sachs

  • Long-Term Results for Children With High-Risk Neuroblastoma Treated on a Randomized Trial of Myeloablative Therapy Followed by 13-cis-Retinoic Acid: A Children's Oncology Group Study

    Katherine K. Matthay;C. Patrick Reynolds;Robert C. Seeger;Hiroyuki Shimada

  • Terminology and morphologic criteria of neuroblastic tumors : recommendations by the International Neuroblastoma Pathology Committee

    Hiroyuki Shimada M.D.;Inge M. Ambros;Louis P. Dehner;Jun-ichi Hata

  • Dominant and differential deposition of distinct β-amyloid peptide species, AβN3(pE), in senile plaques

    Takaomi C Saido;Takeshi Iwatsubo;David M.A Mann;Hiroyuki Shimada

  • Chromosome 1p and 11q deletions and outcome in neuroblastoma.

    Edward F. Attiyeh;Wendy B. London;Yael P. Mossé;Qun Wang

  • Inhibition of Invasion and Metastasis in Cells Transfected with an Inhibitor of Metalloproteinases

    Yves A. DeClerck;Norma Perez;Hiroyuki Shimada;Thomas C. Boone

  • The comparative ability of eight functional mobility tests for predicting falls in community-dwelling older people

    Anne Tiedemann;Hiroyuki Shimada;Catherine Sherrington;Susan Murray

  • A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease.

    Nicolas R Barthélemy;Yan Li;Nelly Joseph-Mathurin;Brian A Gordon

  • A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia

    Takami Tomiyama;Tetsu Nagata;Hiroyuki Shimada;Rie Teraoka

  • Metastatic sites in stage IV and IVS neuroblastoma correlate with age, tumor biology, and survival.

    Steven DuBois;Yan Kalika;John Lukens;Garrett Brodeur

  • A Randomized Controlled Trial of Multicomponent Exercise in Older Adults with Mild Cognitive Impairment

    Takao Suzuki;Hiroyuki Shimada;Hyuma Makizako;Takehiko Doi

  • A Mouse Model of Amyloid β Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo

    Takami Tomiyama;Shogo Matsuyama;Hiroyuki Iso;Tomohiro Umeda;Tomohiro Umeda

  • Combined Prevalence of Frailty and Mild Cognitive Impairment in a Population of Elderly Japanese People

    Hiroyuki Shimada;Hyuma Makizako;Takehiko Doi;Daisuke Yoshida

  • Exosome-Mediated Transfer of microRNAs Within the Tumor Microenvironment and Neuroblastoma Resistance to Chemotherapy

    Kishore B. Challagundla;Petra M. Wise;Paolo Neviani;Haritha Chava

  • Preferential susceptibility of brain tumors to the antiangiogenic effects of an alpha(v) integrin antagonist.

    Tobey J. MacDonald;Takashi Taga;Hiroyuki Shimada;Peyman Tabrizi

  • International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children's Cancer Group.

    Hiroyuki Shimada M.D.;Shunsuke Umehara;Yasumasa Monobe;Yoichi Hachitanda

  • Outcome after Reduced Chemotherapy for Intermediate-Risk Neuroblastoma

    David L. Baker;Mary L. Schmidt;Susan L. Cohn;John M. Maris

  • Prevalence of frailty in Japan: A systematic review and meta-analysis.

    Gotaro Kojima;Steve Iliffe;Yu Taniguchi;Hiroyuki Shimada

  • Histopathology of childhood sarcomas, Intergroup Rhabdomyosarcoma Studies I and II: clinicopathologic correlation.

    W A Newton;E H Soule;A B Hamoudi;H M Reiman

Frequent Co-Authors

Katherine K. Matthay
Katherine K. Matthay University of California, San Francisco
Robert C. Seeger
Robert C. Seeger Children's Hospital of Los Angeles
Wendy B. London
Wendy B. London Harvard University
John M. Maris
John M. Maris Children's Hospital of Philadelphia
Susan L. Cohn
Susan L. Cohn University of Chicago
Richard Sposto
Richard Sposto University of Southern California
Timothy J. Triche
Timothy J. Triche Van Andel Institute
Daniel O. Stram
Daniel O. Stram University of Southern California
Takao Takahashi
Takao Takahashi Keio University
Hidenori Arai
Hidenori Arai Kyoto University

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