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D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
17133
World Ranking
6363
National Ranking
2978

Overview

Kwang-Soo Kim is affiliated with Harvard University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience. Within these areas, Kim's work is further specialized in subfields including Molecular Biology, Cellular and Molecular Neuroscience, Neurology, Physiology, and Cell Biology.

The scientist's research topics prominently cover Pluripotent Stem Cells Research, CRISPR and Genetic Engineering, Nuclear Receptors and Signaling, Neurological Disorders and Treatments, Biomedical Ethics and Regulation, Nerve Injury and Regeneration, and Autism Spectrum Disorder Research.

Kim has published multiple papers with notable titles, years of publication, and venues:

  • Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson's Disease, 2020, New England Journal of Medicine
  • Co-transplantation of autologous Treg cells in a cell therapy for Parkinson's disease, 2023, Nature
  • PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function, 2020, Nature Chemical Biology
  • SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes, 2021, Cell Reports
  • TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease, 2021, Neuron

Frequent collaborators in Kim's work include Young Cha, Pierre Leblanc, Jeffrey S. Schweitzer, Bin Song, and Tae Yoon Park.

Kim's research is published in various journals with multiple contributions to Cell Stem Cell, Nature Communications, and The Journal of Immunology, with additional publications appearing in the New England Journal of Medicine and Nature.

Best Publications

  • Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

    Lars M. Björklund;Rosario Sánchez-Pernaute;Sangmi Chung;Therese Andersson;Therese Andersson

  • A vector-free microfluidic platform for intracellular delivery

    Armon Reza Sharei;Janeta Zoldan;Andrea Adamo;Woo Young Sim

  • Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation.

    Yong Sun Lee;Hak Kyun Kim;Hak Kyun Kim;Sangmi Chung;Kwang Soo Kim

  • Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence.

    Qiang Feng;Shi‐Jiang Lu;Irina Klimanskaya;Ignatius Gomes

  • LRRK2 regulates synaptic vesicle endocytosis.

    Narae Shin;Hyerhan Jeong;Jungsun Kwon;Hye Young Heo

  • Selective loss of dopaminergic neurons in the substantia nigra of Pitx3-deficient aphakia mice

    Dong-Youn Hwang;Paul Ardayfio;Un Jung Kang;Elena V Semina

  • In vitro and in vivo analyses of human embryonic stem cell‐derived dopamine neurons

    Chang-Hwan Park;Yang Ki Minn;Ji Yeon Lee;Dongho Choi

  • A quantitative-trait analysis of human plasma-dopamine β-hydroxylase activity: Evidence for a major functional polymorphism at the DBH locus

    Cyrus P. Zabetian;George M. Anderson;Sarah G. Buxbaum;Robert C. Elston

  • Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons

    Sangmi Chung;Kai-C. Sonntag;Therese Andersson;Lars M. Bjorklund

  • Essential Role for TRPC5 in Amygdala Function and Fear-Related Behavior

    Antonio Riccio;Yan Li;Jisook Moon;Kwang-Soo Kim

  • Impact of Circadian Nuclear Receptor REV-ERBα on Midbrain Dopamine Production and Mood Regulation

    Sooyoung Chung;Eun Jeong Lee;Seongsik Yun;Han Kyoung Choe

  • Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease.

    Yong-Hee Rhee;Ji-Yun Ko;Mi-Yoon Chang;Sang-Hoon Yi

  • Inhibition of pluripotent stem cell-derived teratoma formation by small molecules.

    Mi Ok Lee;Sung Hwan Moon;Ho Chang Jeong;Ji Yeon Yi

  • Mitochondrial Cyclic AMP Response Element-binding Protein (CREB) Mediates Mitochondrial Gene Expression and Neuronal Survival

    Junghee Lee;Junghee Lee;Chun Hyung Kim;David K. Simon;Lyaylya R. Aminova

  • hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice.

    Miles Cunningham;Jun-Hyeong Cho;Amanda Leung;George Savvidis

  • Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell-specific manner.

    Kwang Soo Kim;Chun Hyung Kim;Dong Youn Hwang;Hyemyung Seo

  • Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem Cells

    Qiang Feng;Namrata Shabrani;Jonathan N. Thon;Hongguang Huo

  • Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway.

    Sangmi Chung;Amanda Leung;Baek Soo Han;Mi Yoon Chang

  • A High-Efficiency Synthetic Promoter That Drives Transgene Expression Selectively in Noradrenergic Neurons

    Dong-Youn Hwang;William A. Carlezon;Ole Isacson;Kwang-Soo Kim

  • Analysis of Different Promoter Systems for Efficient Transgene Expression in Mouse Embryonic Stem Cell Lines

    Sangmi Chung;Therese Andersson;Kai‐C. Sonntag;Lars Björklund

Frequent Co-Authors

Ole Isacson
Ole Isacson Harvard University
Un Jung Kang
Un Jung Kang New York University
William A. Carlezon
William A. Carlezon Harvard University
David Robertson
David Robertson Vanderbilt University
Bruce M. Cohen
Bruce M. Cohen Harvard University
Dong-Wook Kim
Dong-Wook Kim Ewha Womans University
Henryk M. Wisniewski
Henryk M. Wisniewski University of York
Vadim Y. Bolshakov
Vadim Y. Bolshakov Harvard University
Hyung-Min Chung
Hyung-Min Chung Konkuk University
Johannes Schwarz
Johannes Schwarz Leipzig University

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