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Shigeru Fujita

Shigeru Fujita

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
7404
World Ranking
17760
National Ranking
1283

Overview

Shigeru Fujita is affiliated with Ehime University in Japan and has contributed extensively to the field of Medicine, particularly focusing on Infectious Diseases. Their research spans several subfields including Animal Science and Zoology, Molecular Biology, Epidemiology, and Emergency Medical Services.

The primary topics covered by Fujita's work include:

  • SARS-CoV-2 and COVID-19 Research
  • Animal Virus Infections Studies
  • SARS-CoV-2 detection and testing
  • Viral gastroenteritis research and epidemiology
  • Bacillus and Francisella bacterial research
  • COVID-19 Clinical Research Studies
  • Respiratory viral infections research

Fujita has published multiple papers in high-impact journals on virological characteristics and neutralization sensitivity of SARS-CoV-2 variants. Some recent papers include:

  • Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants, 2023, Nature Communications
  • Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5, 2022, Cell
  • Neutralisation sensitivity of SARS-CoV-2 omicron subvariants to therapeutic monoclonal antibodies, 2022, The Lancet Infectious Diseases
  • Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant, 2022, Cell Host & Microbe
  • Enhanced transmissibility, infectivity, and immune resistance of the SARS-CoV-2 omicron XBB.1.5 variant, 2023, The Lancet Infectious Diseases

Their frequent co-authors include:

  • Jumpei Ito
  • Yusuke Kosugi
  • Keiya Uriu
  • Kei Sato
  • Tomokazu Tamura

Fujita's work has been published predominantly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, PLoS ONE, The Lancet Infectious Diseases, and Journal of Virology, with the highest number of publications in bioRxiv and Nature Communications.

Best Publications

  • HLA class I-restricted lysis of leukemia cells by a CD8(+) cytotoxic T-lymphocyte clone specific for WT1 peptide.

    Hideki Ohminami;Masaki Yasukawa;Shigeru Fujita

  • Abrogation of the alternative complement pathway by targeted deletion of murine factor B

    Mitsuru Matsumoto;Wataru Fukuda;Antonella Circolo;Joseph Goellner

  • Antagonist of monocyte chemoattractant protein 1 ameliorates the initiation and progression of lupus nephritis and renal vasculitis in MRL/lpr mice.

    Hitoshi Hasegawa;Masashi Kohno;Miho Sasaki;Atsushi Inoue

  • Abnormal Immune Function of Hemopoietic Cells from Alymphoplasia (aly) Mice, a Natural Strain with Mutant NF-κB-Inducing Kinase

    Takuji Yamada;Tasuku Mitani;Kazuko Yorita;Daisuke Uchida

  • Mutations in the envelope protein of Japanese encephalitis virus affect entry into cultured cells and virulence in mice.

    Hitoshi Hasegawa;Masamichi Yoshida;Takahiko Shiosaka;Shigeru Fujita

  • The p38 MAPK Pathway Mediates the Growth Inhibitory Effects of Interferon-α in BCR-ABL-expressing Cells

    Ingrid A. Mayer;Amit Verma;Isabella M. Grumbach;Shahab Uddin

  • Granule exocytosis, and not the fas/fas ligand system, is the main pathway of cytotoxicity mediated by alloantigen-specific CD4(+) as well as CD8(+) cytotoxic T lymphocytes in humans.

    Masaki Yasukawa;Masaki Yasukawa;Hideki Ohminami;Hideki Ohminami;Junko Arai;Junko Arai;Yoshihito Kasahara;Yoshihito Kasahara

  • Increased chemokine receptor CCR7/EBI1 expression enhances the infiltration of lymphoid organs by adult T-cell leukemia cells.

    Hitoshi Hasegawa;Hitoshi Hasegawa;Tetsuhiko Nomura;Tetsuhiko Nomura;Masashi Kohno;Masashi Kohno;Norihiko Tateishi;Norihiko Tateishi

  • Antagonist of fractalkine (CX3CL1) delays the initiation and ameliorates the progression of lupus nephritis in MRL/lpr mice

    Atsushi Inoue;Hitoshi Hasegawa;Masashi Kohno;Mitsuko R. Ito

  • Outside-to-inside signal through the membrane TNF-alpha induces E-selectin (CD62E) expression on activated human CD4+ T cells.

    Shin-ichi Harashima;Takahiko Horiuchi;Nobuaki Hatta;Chika Morita

  • Identification of human telomerase reverse transcriptase-derived peptides that induce HLA-A24-restricted antileukemia cytotoxic T lymphocytes.

    Junko Arai;Masaki Yasukawa;Hideki Ohminami;Miki Kakimoto

  • CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase.

    Masashi Kohno;Hitoshi Hasegawa;Masayuki Miyake;Tadashi Yamamoto

  • Constitutive expression of SOCS3 confers resistance to IFN-α in chronic myelogenous leukemia cells

    Ikuya Sakai;Kazuto Takeuchi;Hayato Yamauchi;Hirosi Narumi

  • Induction of T-cell apoptosis by human herpesvirus 6.

    Y Inoue;M Yasukawa;S Fujita

  • SFA-1, a novel cellular gene induced by human T-cell leukemia virus type 1, is a member of the transmembrane 4 superfamily.

    H Hasegawa;Y Utsunomiya;K Kishimoto;K Yanagisawa

  • Essential Role of NF-κB-Inducing Kinase in T Cell Activation Through the TCR/CD3 Pathway

    Mitsuru Matsumoto;Takuji Yamada;Steven K. Yoshinaga;Tom Boone

  • Stromal cells in lymph nodes attract B-lymphoma cells via production of stromal cell-derived factor-1.

    Junko Arai;Masaki Yasukawa;Yoshihiro Yakushijin;Tatsuhiko Miyazaki

  • CD4(+) cytotoxic T-cell clones specific for bcr-abl b3a2 fusion peptide augment colony formation by chronic myelogenous leukemia cells in a b3a2-specific and HLA-DR-restricted manner

    Masaki Yasukawa;Hideki Ohminami;Shin Kaneko;Yoshihiro Yakushijin

  • Fas-Independent Cytotoxicity Mediated by Human CD4+ CTL Directed Against Herpes Simplex Virus-Infected Cells

    Masaki Yasukawa;Hideki Ohminami;Yoshihiro Yakushijin;Junko Arai

  • Distinct effects of human herpesvirus 6 and human herpesvirus 7 on surface molecule expression and function of CD4+ T cells.

    M Furukawa;M Yasukawa;Y Yakushijin;S Fujita

Frequent Co-Authors

Masaki Yasukawa
Masaki Yasukawa Ehime University
Mitsuru Matsumoto
Mitsuru Matsumoto University of Tokushima
Osamu Yoshie
Osamu Yoshie Kindai University
Koji Hashimoto
Koji Hashimoto Ehime University
Masato Nose
Masato Nose Ehime University
Yasuharu Nishimura
Yasuharu Nishimura Kumamoto University
Yukio Ozaki
Yukio Ozaki University of Yamanashi
Masaru Okabe
Masaru Okabe Osaka University
Jun-ichi Miyazaki
Jun-ichi Miyazaki Osaka University
Yoshiyuki Niho
Yoshiyuki Niho Kyushu University

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