Molecular biology, Insulin, Insulin receptor, Internal medicine and Endocrinology are his primary areas of study. His Molecular biology research includes elements of Peptide sequence, Gene, Transfection, GLUT4 and PI3K/AKT/mTOR pathway. The various areas that he examines in his Peptide sequence study include Nucleic acid sequence, Receptor tyrosine kinase, Transmembrane domain and G alpha subunit.
A large part of his Insulin studies is devoted to Glucose transporter. His Insulin receptor research is multidisciplinary, incorporating elements of Autophosphorylation, Interleukin 10 receptor, alpha subunit and Biochemistry. His work on Insulin resistance and Glucagon as part of general Internal medicine research is frequently linked to Membrane hyperpolarization and Alpha cell, thereby connecting diverse disciplines of science.
His scientific interests lie mostly in Endocrinology, Internal medicine, Molecular biology, Insulin receptor and Insulin. His study in the field of Insulin Receptor alpha Subunit is also linked to topics like Hypoinsulinemia. His studies in Molecular biology integrate themes in fields like Plasmid, Nucleic acid sequence, Transfection, Gene and Colicin.
His research in Insulin receptor intersects with topics in Receptor, Tyrosine kinase and Tyrosine phosphorylation. His work carried out in the field of Insulin brings together such families of science as Autophosphorylation and Skeletal muscle. His studies deal with areas such as Glucose transporter, Angiotensin II and Protein kinase B as well as Glucose uptake.
Yousuke Ebina mainly investigates Internal medicine, Endocrinology, Insulin, Insulin receptor and Receptor. Yousuke Ebina has researched Internal medicine in several fields, including Diabetes mellitus and Protein kinase B. The study incorporates disciplines such as Glucose transporter, GLUT4, Molecular biology and PI3K/AKT/mTOR pathway in addition to Protein kinase B.
His work on Insulin Receptor alpha Subunit as part of general Endocrinology study is frequently linked to Hypoinsulinemia, therefore connecting diverse disciplines of science. His Insulin research incorporates elements of Creatinine and Tyrosine kinase. Insulin receptor substrate is the focus of his Insulin receptor research.
His primary scientific interests are in Protein kinase B, Internal medicine, Endocrinology, Insulin resistance and Insulin. Yousuke Ebina interconnects GLUT4, Molecular biology, PI3K/AKT/mTOR pathway and Insulin receptor in the investigation of issues within Protein kinase B. His GLUT4 research includes themes of Glucose tolerance test and Adiponectin.
His Molecular biology research is multidisciplinary, incorporating perspectives in Glycogen synthase, AKT1, AKT3, Protein kinase C and Glucose homeostasis. His biological study focuses on Glucose uptake. The Insulin resistance study combines topics in areas such as Glucagon and Glucagon secretion.
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The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling
Yousuke Ebina;Leland Ellis;Kurt Jarnagin;Marc Edery.
Cell (1985)
Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity
Yousuke Ebina;Eiichi Araki;Masato Taira;Fumio Shimada.
Proceedings of the National Academy of Sciences of the United States of America (1987)
Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase.
F. Kanai;K. Ito;M. Todaka;H. Hayashi.
Biochemical and Biophysical Research Communications (1993)
Complete nucleotide sequence of the metapyrocatechase gene on the TOI plasmid of Pseudomonas putida mt-2.
C Nakai;H Kagamiyama;M Nozaki;T Nakazawa.
Journal of Biological Chemistry (1983)
Use of RNA Interference-mediated Gene Silencing and Adenoviral Overexpression to Elucidate the Roles of AKT/Protein Kinase B Isoforms in Insulin Actions
Takashi Katome;Toshiyuki Obata;Toshiyuki Obata;Rie Matsushima;Norihisa Masuyama.
Journal of Biological Chemistry (2003)
GLUT4 translocation by insulin in intact muscle cells: detection by a fast and quantitative assay
Qinghua Wang;Zayna Khayat;Kazuhiro Kishi;Yousuke Ebina.
FEBS Letters (1998)
Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.
Satoshi Ugi;Takeshi Imamura;Hiroshi Maegawa;Katsuya Egawa.
Molecular and Cellular Biology (2004)
IRS1-Independent Defects Define Major Nodes of Insulin Resistance
Kyle L. Hoehn;Cordula Hohnen-Behrens;Anna Cederberg;Lindsay E. Wu.
Cell Metabolism (2008)
Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system
Elaine Xu;Elaine Xu;Mohan Kumar;Mohan Kumar;Yi Zhang;Yi Zhang;William Ju;William Ju.
Cell Metabolism (2006)
Bradykinin directly triggers GLUT4 translocation via an insulin-independent pathway.
K Kishi;N Muromoto;Y Nakaya;I Miyata.
Diabetes (1998)
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