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Biology and Biochemistry

D-Index
60
Citations
19294
World Ranking
11728
National Ranking
5043

Overview

Jeff Kuret is a researcher affiliated with The Ohio State University in the United States, with a focused academic background in medicine and biochemistry, genetics, and molecular biology. Their research extensively covers several subfields including physiology, molecular biology, cell biology, pharmacology, and neurology.

The main research themes in their work revolve around Alzheimer's disease research and treatments, which is reflected across 22 publications. Additional topics of study include protein structure and dynamics, cholinesterase and neurodegenerative diseases, endoplasmic reticulum stress and disease, computational drug discovery methods, autophagy in disease and therapy, and prion diseases and protein misfolding.

Jeff Kuret has published frequently in notable scientific venues. The most common publication outlets include Biophysical Journal and Alzheimer's & Dementia, each with two articles, as well as Methods in Molecular Biology, Molecular Neurobiology, and Acta Neuropathologica. These venues highlight the interdisciplinary nature of their research bridging molecular biology and neurodegenerative disease.

Their recent published papers include:

  • Hyperphosphorylation Renders Tau Prone to Aggregate and to Cause Cell Death (2020, Molecular Neurobiology)
  • Wolframin is a Novel Regulator of Tau Pathology and Neurodegeneration (2022, Acta Neuropathologica)
  • A Theoretical Study of Polymorphism in VQIVYK Fibrils (2021, Biophysical Journal)
  • DJ-1 Molecular Chaperone Activity Depresses Tau Aggregation Propensity through Interaction with Monomers (2023, Biochemistry)
  • Identification of Gene Networks Mediating Regional Resistance to Tauopathy in Late-Onset Alzheimer's Disease (2023, PLoS Genetics)

Collaboration plays a role in Jeff Kuret's professional activity, with frequent co-authors including Christopher A. Ayoub, Daniela Jimenez-Harrison, Mengyu Liu, Dexin Sui, and Thomas S. Dexheimer. These collaborators have contributed to multiple research papers, reflecting sustained partnerships in their investigative pursuits.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

    Gilles Carmel;Edward M. Mager;Lester I. Binder;Jeff Kuret

  • C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease

    A. Abraha;N. Ghoshal;T.C. Gamblin;V. Cryns

  • Molecular Interactions among Protein Phosphatase 2A, Tau, and Microtubules IMPLICATIONS FOR THE REGULATION OF TAU PHOSPHORYLATION AND THE DEVELOPMENT OF TAUOPATHIES

    Estelle Sontag;Viyada Nunbhakdi-Craig;Gloria Lee;Roland Brandt

  • Anionic micelles and vesicles induce tau fibrillization in vitro.

    Carmen N. Chirita;Mihaela Necula;Jeff Kuret

  • Rapid Anionic Micelle-mediated α-Synuclein Fibrillization in Vitro

    Mihaela Necula;Carmen N. Chirita;Jeff Kuret

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Crystal structure of a conformation-selective casein kinase-1 inhibitor.

    Neda Mashhoon;Anthony J. DeMaggio;Valentina Tereshko;Stephen C. Bergmeier

  • Casein Kinase 1 Delta Phosphorylates Tau and Disrupts Its Binding to Microtubules

    Guibin Li;Haishan Yin;Jeff Kuret

  • Triggers of full-length tau aggregation: a role for partially folded intermediates.

    Carmen N Chirita;Erin E Congdon;Haishan Yin;Jeff Kuret

  • Differential assembly of human tau isoforms in the presence of arachidonic acid.

    M E King;T C Gamblin;J Kuret;L I Binder

  • A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease.

    Nupur Ghoshal;John F. Smiley;Anthony J. DeMaggio;Merl F. Hoekstra

  • Purification and characterization of a Ca2+/calmodulin-dependent protein kinase from rat brain.

    Jeff Kuret;Howard Schulman

  • Ligand-dependent tau filament formation: implications for Alzheimer's disease progression.

    Michelle E. King;Vibha Ahuja;Lester I. Binder;Jeff Kuret

  • Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases.

    Claudia Schwab;Anthony J. DeMaggio;Nupur Ghoshal;Lester I. Binder

  • Tau Aggregation and Toxicity in a Cell Culture Model of Tauopathy

    Bhaswati Bandyopadhyay;Guibin Li;Haishan Yin;Jeffrey Allan Kuret

  • Oxidative regulation of fatty acid-induced tau polymerization.

    T. Chris Gamblin;Michelle E. King;Jeff Kuret;and Robert W. Berry

  • Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro.

    Mihaela Necula;Jeff Kuret

  • In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants.

    T. Chris Gamblin;Michelle E. King;Hana Dawson;Michael P. Vitek

Frequent Co-Authors

Evelina Gatti
Evelina Gatti Aix-Marseille University
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Sergio Lavandero
Sergio Lavandero University of Chile
Ian G. Mills
Ian G. Mills University of Oxford
Leonidas C. Platanias
Leonidas C. Platanias Northwestern University
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Karen Duff
Karen Duff University College London
Yee-Joo Tan
Yee-Joo Tan National University of Singapore
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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