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Biology and Biochemistry

D-Index
59
Citations
23470
World Ranking
12261
National Ranking
5241

Overview

Patty J. Lee is a researcher affiliated with Duke University in the United States. Their primary field of study encompasses biochemistry, genetics, and molecular biology. Within these broader domains, specific subfields include molecular biology and aging. The main topics addressed in their work focus on single-cell and spatial transcriptomics as well as genetics, aging, and longevity in model organisms.

Lee has contributed to the scientific community through research articles, with recent work published in venues such as Preprints.org. Their known publication includes the paper titled "NIH SenNet Consortium: Mapping Senescent Cells in the Human Body to Understand Health and Disease", published in 2022. This paper contributes to advancing knowledge regarding cellular senescence and its implications for health and disease.

Their collaborations involve several frequent co-authors, indicative of interdisciplinary and joint research endeavors. These collaborators include:

  • Philip D. Blood
  • Katy Börner
  • Judith Campisi
  • Feng Chen
  • Heike E. Daldrup-Link

Lee's research output appears mainly within the journal Preprints.org, representing the venues in which they have published. Their work, situated at the intersection of molecular biology and aging, engages with cutting-edge methodologies such as single-cell and spatial transcriptomics to understand biological processes linked to aging and longevity in model organisms.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Regulation of lung injury and repair by Toll-like receptors and hyaluronan.

    Dianhua Jiang;Jiurong Liang;Juan Fan;Shuang Yu

  • Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia

    Patty J. Lee;Bing Hua Jiang;Beek Yoke Chin;Narayan V. Iyer

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Early Growth Response Gene 1–mediated Apoptosis Is Essential for Transforming Growth Factor β1–induced Pulmonary Fibrosis

    Chun Geun Lee;Soo Jung Cho;Min Jong Kang;Svetlana P. Chapoval

  • Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia

    Patty J. Lee;Jawed Alam;Gordon W. Wiegand;Augustine M. K. Choi

  • Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death

    Vineet Bhandari;Rayman Choo-Wing;Chun G Lee;Zhou Zhu

  • Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

    Xuchen Zhang;Peiying Shan;Dianhua Jiang;Paul W. Noble

  • Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3.

    Xuchen Zhang;Peiying Shan;Leo E. Otterbein;Jawed Alam

  • Parallel Induction of Heme Oxygenase-1 and Chemoprotective Phase 2 Enzymes by Electrophiles and Antioxidants: Regulation by Upstream Antioxidant-Responsive Elements (ARE)

    Tory Prestera;Paul Talalay;Jawed Alam;Young I. Ahn

  • Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.

    Hiroaki Katsura;Vishwaraj Sontake;Aleksandra Tata;Yoshihiko Kobayashi

  • Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects.

    Ruiping Song;Masatoshi Kubo;Danielle Morse;Zhihong Zhou

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function

    Guoying Yu;Argyris Tzouvelekis;Rong Wang;Jose D Herazo-Maya

  • Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury.

    Xuchen Zhang;Peiying Shan;Jawed Alam;Xin-Yuan Fu

  • Hypoxia-inducible factor 1α stabilization by carbon monoxide results in cytoprotective preconditioning

    Beek Y. Chin;Ge Jiang;Barbara Wegiel;Hong J. Wang

  • Regulation of Heme Oxygenase-1 Expression in Vivo and in Vitro in Hyperoxic Lung Injury

    Patty J. Lee;Jawed Alam;Sherrie L. Sylvester;Nilufar Inamdar

  • Toll-like receptor 4 deficiency causes pulmonary emphysema

    Xuchen Zhang;Peiying Shan;Ge Jiang;Lauren Cohn

  • UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

    Jong Seok Moon;Jong Seok Moon;Seonmin Lee;Seonmin Lee;Mi Ae Park;Ilias I. Siempos;Ilias I. Siempos;Ilias I. Siempos

  • Cell Death in the Lung: The Apoptosis-Necroptosis Axis.

    Maor Sauler;Isabel S. Bazan;Patty J. Lee

Frequent Co-Authors

Augustine M. K. Choi
Augustine M. K. Choi Cornell University
Robert J. Homer
Robert J. Homer Yale University
Richard Bucala
Richard Bucala Yale University
Yi Zhang
Yi Zhang Harvard University
Jack A. Elias
Jack A. Elias Brown University
Naftali Kaminski
Naftali Kaminski Yale University
Jawed Alam
Jawed Alam University Medical Center New Orleans
Leo E. Otterbein
Leo E. Otterbein Beth Israel Deaconess Medical Center
Lin Leng
Lin Leng Yale University
Irina Petrache
Irina Petrache University of Cambridge

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