Jawed Alam

Overview

Best Publications

• Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications.

  Stefan W. Ryter;Jawed Alam;Augustine M. K. Choi

  3122
  Citations

• Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

  Leo E. Otterbein;Leo E. Otterbein;Fritz H. Bach;Jawed Alam;Miguel P. Soares

  2654
  Citations

• Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene.

  Jawed Alam;Daniel Stewart;Cheri Touchard;Sujji Boinapally

  1796
  Citations

• Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury.

  Augustine M.K. Choi;Jawed Alam

  1649
  Citations

• Regulation of Heme Oxygenase-1 Expression through the Phosphatidylinositol 3-Kinase/Akt Pathway and the Nrf2 Transcription Factor in Response to the Antioxidant Phytochemical Carnosol

  Daniel Martin;Ana I. Rojo;Marta Salinas;Raquel Diaz;Raquel Diaz;Raquel Diaz

  1019
  Citations

• Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia

  Patty J. Lee;Bing Hua Jiang;Beek Yoke Chin;Narayan V. Iyer

  977
  Citations

• Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene

  Jiying Sun;Jiying Sun;Hideto Hoshino;Hideto Hoshino;Kazuaki Takaku;Osamu Nakajima

  777
  Citations

• Reporter genes: application to the study of mammalian gene transcription.

  Jawed Alam;Julia L. Cook

  707
  Citations

• Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury.

  Farin Amersi;Roland Buelow;Hirohisa Kato;Bibo Ke

  646
  Citations

• Identification of Activating Transcription Factor 4 (ATF4) as an Nrf2-interacting Protein IMPLICATION FOR HEME OXYGENASE-1 GENE REGULATION

  Chuan Hua He;Chuan Hua He;Pengfei Gong;Bin Hu;Daniel Stewart

  643
  Citations

• Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury

  Leo E. Otterbein;Jay K. Kolls;Lin L. Mantell;Julia L. Cook

  638
  Citations

• Nrf2 Is a Key Transcription Factor That Regulates Antioxidant Defense in Macrophages and Epithelial Cells: Protecting against the Proinflammatory and Oxidizing Effects of Diesel Exhaust Chemicals

  Ning Li;Jawed Alam;M. Indira Venkatesan;Arantza Eiguren-Fernandez

  633
  Citations

• Mechanism of Heme Oxygenase-1 Gene Activation by Cadmium in MCF-7 Mammary Epithelial Cells ROLE OF p38 KINASE AND Nrf2 TRANSCRIPTION FACTOR

  Jawed Alam;Claire Wicks;Daniel Stewart;Pengfei Gong

  589
  Citations

• How Many Transcription Factors Does It Take to Turn On the Heme Oxygenase-1 Gene?

  Jawed Alam;Julia L. Cook

  509
  Citations

• Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia

  Patty J. Lee;Jawed Alam;Gordon W. Wiegand;Augustine M. K. Choi

  448
  Citations

• Heme oxygenase-1 inhibits TNF-α-induced apoptosis in cultured fibroblasts

  Irina Petrache;Leo E. Otterbein;Leo E. Otterbein;Jawed Alam;Gordon W. Wiegand

  446
  Citations

• Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3.

  Xuchen Zhang;Peiying Shan;Leo E. Otterbein;Jawed Alam

  349
  Citations

• Parallel Induction of Heme Oxygenase-1 and Chemoprotective Phase 2 Enzymes by Electrophiles and Antioxidants: Regulation by Upstream Antioxidant-Responsive Elements (ARE)

  Tory Prestera;Paul Talalay;Jawed Alam;Young I. Ahn

  346
  Citations

• Transcriptional activation of the heme oxygenase gene by heme and cadmium in mouse hepatoma cells.

  J Alam;S Shibahara;A Smith

  319
  Citations

• Induction of heme oxygenase in toxic renal injury: A protective role in cisplatin nephrotoxicity in the rat

  Anupam Agarwal;József Balla;Jawed Alam;Anthony J. Croatt

  319
  Citations