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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
12416
World Ranking
13149
National Ranking
5608

Overview

Kosaku Uyeda is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research spans multiple fields within biochemistry, genetics, and molecular biology, as well as medicine.

The main fields of study for their work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these disciplines, their subfields of study are:

  • Molecular Biology
  • Surgery
  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Cancer Research

Kosaku Uyeda's research covers a variety of topics, notably:

  • Cholesterol and Lipid Metabolism
  • Plant biochemistry and biosynthesis
  • 14-3-3 protein interactions
  • Diet, Metabolism, and Disease
  • Lipid metabolism and biosynthesis
  • Metabolism, Diabetes, and Cancer
  • Cancer, Hypoxia, and Metabolism

Their recent published papers include:

  • The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-importin α interactions, 2020, Biochemical Journal
  • Short- and Long-Term Adaptation to Altered Levels of Glucose: Fifty Years of Scientific Adventure, 2021, Annual Review of Biochemistry

Frequent collaborators in their research efforts are:

  • Richard Wynn
  • Hunmin Jung
  • Tomomi Takeshima
  • Tsutomu Nakagawa
  • Karen S. MacMillan

Kosaku Uyeda has published in journals such as:

  • Biochemical Journal
  • Annual Review of Biochemistry

Best Publications

  • Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

    Katsumi Iizuka;Richard K. Bruick;Guosheng Liang;Jay D. Horton

  • A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver

    Hiromi Yamashita;Makoto Takenoshita;Masaharu Sakurai;Richard K. Bruick

  • Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis

    Kosaku Uyeda;Joyce J. Repa

  • Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase.

    Takumi Kawaguchi;Kiyoshi Osatomi;Hiromi Yamashita;Tsutomu Kabashima

  • Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver.

    Tsutomu Kabashima;Takumi Kawaguchi;Takumi Kawaguchi;Brian E. Wadzinski;Kosaku Uyeda

  • Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription

    Seiji Ishii;Katsumi IIzuka;Katsumi IIzuka;Bonnie C. Miller;Kosaku Uyeda

  • Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein

    Takumi Kawaguchi;Makoto Takenoshita;Tsutomu Kabashima;Kosaku Uyeda

  • Regulatory Mechanisms in Carbohydrate Metabolism VII. HEXOKINASE AND PHOSPHOFRUCTOKINASE

    Kosaku Uyeda;Efraim Racker

  • Carbohydrate responsive element-binding protein (ChREBP): a key regulator of glucose metabolism and fat storage.

    Kosaku Uyeda;Hiromi Yamashita;Takumi Kawaguchi

  • The effect of natural and synthetic D-fructose 2,6-bisphosphate on the regulatory kinetic properties of liver and muscle phosphofructokinases.

    Kosaku Uyeda;Eisuke Furuya;Lynne J. Luby

  • Pyruvate-ferredoxin oxidoreductase. 3. Purification and properties of the enzyme.

    Kosaku Uyeda;Jesse C. Rabinowitz

  • Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient (ob/ob) mice.

    Katsumi Iizuka;Bonnie Miller;Kosaku Uyeda

  • Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice.

    Albert G. Linden;Shili Li;Hwa Y. Choi;Fei Fang

  • A special fructose bisphosphate functions as a cytoplasmic regulatory metabolite in green leaves.

    Csaba Cséke;Norman F. Weeden;Bob B. Buchanan;Kosaku Uyeda

  • Hormone-stimulated phosphorylation of liver phosphofructokinase in vivo.

    T. Kagimoto;Kosaku Uyeda

  • The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies.

    Charles A Hasemann;Eva S Istvan;Kosaku Uyeda;Johann Deisenhofer

  • Fructose-2,6-P2, chemistry and biological function.

    Kosaku Uyeda;Eisuke Furuya;Eisuke Furuya;Carolyn S. Richards;Carolyn S. Richards;Motoko Yokoyama;Motoko Yokoyama

  • Purification and Characterization of a Novel Xylulose 5-Phosphate-activated Protein Phosphatase Catalyzing Dephosphorylation of Fructose-6-phosphate,2-kinase:Fructose-2,6-bisphosphatase

    Motonobu Nishimura;Kosaku Uyeda

  • Molecular cloning of the DNA and expression and characterization of rat testes fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase.

    Junichiro Sakata;Yumiko Abe;Kosaku Uyeda

  • Changes in allosteric properties of phosphofructokinase bound to erythrocyte membranes.

    N. S. Karadsheh;Kosaku Uyeda

Frequent Co-Authors

Hiroyuki Mizuguchi
Hiroyuki Mizuguchi Osaka University
Hiromi Yamashita
Hiromi Yamashita Osaka University
Richard L. Veech
Richard L. Veech National Institutes of Health
Paul F. Cook
Paul F. Cook University of Oklahoma
Jesse C. Rabinowitz
Jesse C. Rabinowitz University of California, Berkeley
Johann Deisenhofer
Johann Deisenhofer The University of Texas Southwestern Medical Center
Jay D. Horton
Jay D. Horton The University of Texas Southwestern Medical Center
Shawn C. Burgess
Shawn C. Burgess The University of Texas Southwestern Medical Center
Joyce J. Repa
Joyce J. Repa The University of Texas Southwestern Medical Center
Jef K. De Brabander
Jef K. De Brabander The University of Texas Southwestern Medical Center

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