D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 56 Citations 10,813 124 World Ranking 8066 National Ranking 2420
Biology and Biochemistry D-index 56 Citations 10,822 124 World Ranking 9956 National Ranking 4374

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His primary areas of study are Biochemistry, Carbohydrate-responsive element-binding protein, Phosphofructokinase, Transcription factor and Glycolysis. His Phosphorylation, Carbohydrate metabolism, Enzyme activator, Protein kinase A and Phosphofructokinase 2 study are his primary interests in Biochemistry. His study in Carbohydrate-responsive element-binding protein is interdisciplinary in nature, drawing from both Endocrinology, Lipogenesis, Gene expression, Fatty acid and Pyruvate kinase.

Phosphofructokinase and Fructose are frequently intertwined in his study. His Fructose study integrates concerns from other disciplines, such as Complementary DNA, Fructose 2,6-bisphosphate, PFKFB4 and Protein kinase C. Kosaku Uyeda has included themes like Chemical synthesis and Stereochemistry in his Enzyme study.

His most cited work include:

  • Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis (555 citations)
  • A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver (532 citations)
  • Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis (385 citations)

What are the main themes of his work throughout his whole career to date?

Kosaku Uyeda focuses on Biochemistry, Fructose, Phosphofructokinase 2, Phosphofructokinase and Enzyme. Biochemistry is closely attributed to Molecular biology in his research. His research integrates issues of Wild type, Endocrinology, Kinase and Stereochemistry in his study of Fructose.

His Phosphofructokinase 2 research focuses on subjects like Peptide sequence, which are linked to Peptide. His Phosphofructokinase research focuses on Allosteric regulation and how it connects with Phosphate. His Carbohydrate-responsive element-binding protein research integrates issues from Pyruvate kinase, Lipogenesis, Carbohydrate and Carbohydrate metabolism.

He most often published in these fields:

  • Biochemistry (91.91%)
  • Fructose (44.85%)
  • Phosphofructokinase 2 (39.71%)

What were the highlights of his more recent work (between 2007-2020)?

  • Biochemistry (91.91%)
  • Transcription factor (23.53%)
  • Carbohydrate-responsive element-binding protein (22.06%)

In recent papers he was focusing on the following fields of study:

Kosaku Uyeda mainly investigates Biochemistry, Transcription factor, Carbohydrate-responsive element-binding protein, Nuclear localization sequence and Plasma protein binding. Kosaku Uyeda integrates many fields in his works, including Biochemistry and Element binding protein. His Transcription factor research is multidisciplinary, incorporating elements of Protein structure, Fructose and Phosphorylation, Cell biology.

In the subject of general Phosphorylation, his work in Dephosphorylation, Protein kinase A and Phosphatase is often linked to Cellular localization, thereby combining diverse domains of study. His Carbohydrate-responsive element-binding protein study combines topics from a wide range of disciplines, such as Lipogenesis, Endocrinology, Carbohydrate metabolism, Cytosol and Fatty acid synthesis. The concepts of his Endocrinology study are interwoven with issues in Messenger RNA, Gene and Transcriptional regulation.

Between 2007 and 2020, his most popular works were:

  • Regulation of Nuclear Import/Export of Carbohydrate Response Element-binding Protein (ChREBP): INTERACTION OF AN α-HELIX OF ChREBP WITH THE 14-3-3 PROTEINS AND REGULATION BY PHOSPHORYLATION* (72 citations)
  • Regulation of Nuclear Import/Export of Carbohydrate Response Element-binding Protein (ChREBP): INTERACTION OF AN α-HELIX OF ChREBP WITH THE 14-3-3 PROTEINS AND REGULATION BY PHOSPHORYLATION* (72 citations)
  • Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice. (58 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Metabolism

Biochemistry, Transcription factor, Carbohydrate-responsive element-binding protein, Plasma protein binding and Cellular localization are his primary areas of study. His studies in Fructose, Pyruvate decarboxylation, Pyruvate dehydrogenase complex, Pyruvate dehydrogenase phosphatase and Pyruvate kinase are all subfields of Biochemistry research. His Transcription factor study combines topics in areas such as Wild type, Glutamine, Glycosylation and Gene expression.

His biological study spans a wide range of topics, including Lipogenesis, Endocrinology, Glycolysis, Transcriptional regulation and Postprandial. His Plasma protein binding research includes elements of Protein structure, Nuclear protein, Importin and Phosphorylation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

Katsumi Iizuka;Richard K. Bruick;Guosheng Liang;Jay D. Horton.
Proceedings of the National Academy of Sciences of the United States of America (2004)

792 Citations

A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver

Hiromi Yamashita;Makoto Takenoshita;Masaharu Sakurai;Richard K. Bruick.
Proceedings of the National Academy of Sciences of the United States of America (2001)

750 Citations

Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis

Kosaku Uyeda;Joyce J. Repa.
Cell Metabolism (2006)

623 Citations

Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver.

Tsutomu Kabashima;Takumi Kawaguchi;Takumi Kawaguchi;Brian E. Wadzinski;Kosaku Uyeda.
Proceedings of the National Academy of Sciences of the United States of America (2003)

498 Citations

Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase.

Takumi Kawaguchi;Kiyoshi Osatomi;Hiromi Yamashita;Tsutomu Kabashima.
Journal of Biological Chemistry (2002)

496 Citations

Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein

Takumi Kawaguchi;Makoto Takenoshita;Tsutomu Kabashima;Kosaku Uyeda.
Proceedings of the National Academy of Sciences of the United States of America (2001)

482 Citations

Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription

Seiji Ishii;Katsumi IIzuka;Katsumi IIzuka;Bonnie C. Miller;Kosaku Uyeda.
Proceedings of the National Academy of Sciences of the United States of America (2004)

469 Citations

Regulatory Mechanisms in Carbohydrate Metabolism VII. HEXOKINASE AND PHOSPHOFRUCTOKINASE

Kosaku Uyeda;Efraim Racker.
Journal of Biological Chemistry (1965)

436 Citations

Carbohydrate responsive element-binding protein (ChREBP): a key regulator of glucose metabolism and fat storage.

Kosaku Uyeda;Hiromi Yamashita;Takumi Kawaguchi.
Biochemical Pharmacology (2002)

259 Citations

The effect of natural and synthetic D-fructose 2,6-bisphosphate on the regulatory kinetic properties of liver and muscle phosphofructokinases.

Kosaku Uyeda;Eisuke Furuya;Lynne J. Luby.
Journal of Biological Chemistry (1981)

254 Citations

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