Howard C. Towle mainly investigates Biochemistry, Transcription factor, Gene expression, Lipogenesis and Endocrinology. His research integrates issues of Molecular biology, Pyruvate kinase, Regulation of gene expression, Response element and Transcription in his study of Transcription factor. His Pyruvate kinase research incorporates themes from Carbohydrate metabolism and Pyruvate carboxylase.
His studies deal with areas such as Consensus sequence, Binding site and Cell nucleus as well as Transcription. As a part of the same scientific study, Howard C. Towle usually deals with the Gene expression, concentrating on Messenger RNA and frequently concerns with Euthyroid, Activator and Protein biosynthesis. His study in Endocrinology is interdisciplinary in nature, drawing from both Receptor and Internal medicine.
Biochemistry, Endocrinology, Internal medicine, Gene expression and Molecular biology are his primary areas of study. His study in Biochemistry focuses on Transcription factor, Gene, Carbohydrate-responsive element-binding protein, Pyruvate kinase and Response element. Carbohydrate metabolism and Fatty acid is closely connected to Lipogenesis in his research, which is encompassed under the umbrella topic of Transcription factor.
His Endocrinology research is multidisciplinary, relying on both Messenger RNA and Malic enzyme. His Internal medicine study incorporates themes from Rat liver and In vivo. In his study, Metabolic regulation is inextricably linked to Cell biology, which falls within the broad field of Gene expression.
Howard C. Towle focuses on Biochemistry, Carbohydrate-responsive element-binding protein, Transcription factor, Lipogenesis and MLX. His work often combines Biochemistry and Fructose 2,6-bisphosphate studies. His Transcription factor research incorporates themes from Nuclear export signal, Protein kinase A, Phosphorylation, Response element and Transcription.
The subject of his Lipogenesis research is within the realm of Gene. Specifically, his work in Gene is concerned with the study of Gene expression. His work deals with themes such as Internal medicine and Endocrinology, which intersect with Gene expression.
His primary areas of investigation include Biochemistry, Carbohydrate-responsive element-binding protein, Transcription factor, Lipogenesis and MLX. His study in the field of Gene, Cell nucleus, Fructose and Response element is also linked to topics like Snf3. His Cell nucleus study combines topics in areas such as Mutation, Psychological repression and Repressor.
The study incorporates disciplines such as Glycolysis, Glucose 6-phosphatase, Phosphofructokinase 2 and Allosteric regulation in addition to Fructose. Promoter covers Howard C. Towle research in Response element. His MLX research includes elements of TBX1 and Microarray analysis techniques, Gene expression, Gene expression profiling.
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ChREBP•Mlx Is the Principal Mediator of Glucose-induced Gene Expression in the Liver
Lin Ma;Luke N. Robinson;Howard C. Towle.
Journal of Biological Chemistry (2006)
Regulation of the expression of lipogenic enzyme genes by carbohydrate.
Howard C. Towle;Elizabeth N. Kaytor;Hsiu-Ming Shih.
Annual Review of Nutrition (1997)
Isolation and characterization of rat cDNA clones for two distinct thyroid hormone receptors.
M B Murray;N D Zilz;N L McCreary;M J MacDonald.
Journal of Biological Chemistry (1988)
Two CACGTG Motifs with Proper Spacing Dictate the Carbohydrate Regulation of Hepatic Gene Transcription
Hsiu-Ming Shih;Zheru Liu;Howard C. Towle.
Journal of Biological Chemistry (1995)
Identification of nuclear factors that enhance binding of the thyroid hormone receptor to a thyroid hormone response element.
Mary Beth Murray;Howard C. Towle.
Molecular Endocrinology (1989)
Mlx Is the Functional Heteromeric Partner of the Carbohydrate Response Element-binding Protein in Glucose Regulation of Lipogenic Enzyme Genes
Angela K. Stoeckman;Lin Ma;Howard C. Towle.
Journal of Biological Chemistry (2004)
Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.
L K Olson;J B Redmon;H C Towle;R P Robertson.
Journal of Clinical Investigation (1993)
The role of SREBP-1c in nutritional regulation of lipogenic enzyme gene expression.
Angela K. Stoeckman;Howard C. Towle.
Journal of Biological Chemistry (2002)
Direct Role of ChREBP·Mlx in Regulating Hepatic Glucose-responsive Genes
Lin Ma;Nikolas G. Tsatsos;Howard C. Towle.
Journal of Biological Chemistry (2005)
Metabolic regulation of gene transcription in mammals.
Howard C. Towle.
Journal of Biological Chemistry (1995)
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