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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
14768
World Ranking
11848
National Ranking
5095

Overview

Shawn C. Burgess is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research focuses extensively on medicine and biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology and physiology as subfields of study.

The main topics in Burgess's research include:

  • Mitochondrial Function and Pathology
  • Liver Disease Diagnosis and Treatment
  • Diet and metabolism studies
  • Metabolism, Diabetes, and Cancer
  • Adipose Tissue and Metabolism
  • Cancer, Hypoxia, and Metabolism
  • Metabolism and Genetic Disorders

Frequent co-authors in Burgess's publications are:

  • Xiaorong Fu (20 joint publications)
  • Stanisław Deja (18 joint publications)
  • Justin A. Fletcher (12 joint publications)
  • Blanka Kucejová (7 joint publications)
  • Nicole K.H. Yiew (6 joint publications)

The scientist commonly publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory) with 7 publications
  • Cell Metabolism with 4 publications
  • Diabetes with 4 publications
  • Proceedings of the International Society for Magnetic Resonance in Medicine - Scientific Meeting and Exhibition with 4 publications
  • Cell Reports with 2 publications

Some of the recent papers authored or co-authored by Shawn C. Burgess are:

  • Ins and Outs of the TCA Cycle: The Central Role of Anaplerosis, 2021, Annual Review of Nutrition
  • Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats, 2021, Cellular and Molecular Gastroenterology and Hepatology
  • INCA 2.0: A tool for integrated, dynamic modeling of NMR- and MS-based isotopomer measurements and rigorous metabolic flux analysis, 2021, Metabolic Engineering
  • Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids, 2022, Cell Reports
  • Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability, 2024, Cell Metabolism

Best Publications

  • Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21

    Takeshi Inagaki;Paul Dutchak;Guixiang Zhao;Xunshan Ding

  • FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

    Matthew J. Potthoff;Takeshi Inagaki;Santhosh Satapati;Xunshan Ding

  • A roadmap for interpreting 13 C metabolite labeling patterns from cells

    Joerg M. Buescher;Maciek R. Antoniewicz;Laszlo G. Boros;Shawn C Burgess

  • Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease.

    Nishanth E. Sunny;Elizabeth J. Parks;Jeffrey D. Browning;Shawn C. Burgess

  • FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway

    Matthew J. Potthoff;Jamie Boney-Montoya;Mihwa Choi;Tianteng He

  • Elevated TCA cycle function in the pathology of diet induced hepatic insulin resistance and fatty liver

    Santhosh Satapati;Nishanth E. Sunny;Blanka Kucejova;Xiaorong Fu

  • Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver

    Santhosh Satapati;Blanka Kucejova;Joao A.G. Duarte;Justin A. Fletcher

  • Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction

    Jeffrey D Browning;Jonathan A Baker;Thomas Rogers;Jeannie Davis

  • Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation

    Chai-Wan Kim;Carol Addy;Jun Kusunoki;Norma N. Anderson

  • 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS).

    Danhong Lu;Danhong Lu;Hindrik Mulder;Hindrik Mulder;Piyu Zhao;Shawn C. Burgess

  • Metabolic cycling in control of glucose-stimulated insulin secretion

    Mette V. Jensen;Jamie W. Joseph;Sarah M. Ronnebaum;Shawn C. Burgess

  • Cytosolic Phosphoenolpyruvate Carboxykinase Does Not Solely Control the Rate of Hepatic Gluconeogenesis in the Intact Mouse Liver

    Shawn C. Burgess;Tian Teng He;Zheng Yan;Jill Lindner

  • A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion.

    Sarah M. Ronnebaum;Olga Ilkayeva;Shawn C. Burgess;Jamie W. Joseph

  • Hepatic Mitochondrial Pyruvate Carrier 1 is Required for Efficient Regulation of Gluconeogenesis and Whole-body Glucose Homeostasis

    Lawrence R. Gray;Mst Rasheda Sultana;Adam J. Rauckhorst;Lalita Oonthonpan

  • Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling

    Kyle S. McCommis;Zhouji Chen;Xiaorong Fu;William G. McDonald

  • FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia

    Tian Lan;Donald A. Morgan;Kamal Rahmouni;Junichiro Sonoda

  • Metabolic manifestations of insulin deficiency do not occur without glucagon action

    Young H Lee;Eric D Berglund;May-Yun Wang;Xiaorong Fu

  • Impaired tricarboxylic acid cycle activity in mouse livers lacking cytosolic phosphoenolpyruvate carboxykinase.

    Shawn C. Burgess;Natasha Hausler;Matthew Merritt;F. Mark H Jeffrey

  • Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver.

    David A. Cappel;Stanisław Deja;João A.G. Duarte;Blanka Kucejova

  • Biochemical Mechanism of Lipid-induced Impairment of Glucose-stimulated Insulin Secretion and Reversal with a Malate Analogue

    Anne Boucher;Danhong Lu;Shawn C. Burgess;Sabine Telemaque-Potts

Frequent Co-Authors

A. Dean Sherry
A. Dean Sherry The University of Texas Southwestern Medical Center
Craig R. Malloy
Craig R. Malloy The University of Texas Southwestern Medical Center
Christopher B. Newgard
Christopher B. Newgard Duke University
Olga Ilkayeva
Olga Ilkayeva Duke University
Steven A. Kliewer
Steven A. Kliewer The University of Texas Southwestern Medical Center
Mark A. Magnuson
Mark A. Magnuson Vanderbilt University
David J. Mangelsdorf
David J. Mangelsdorf The University of Texas Southwestern Medical Center
Ralph J. DeBerardinis
Ralph J. DeBerardinis The University of Texas Southwestern Medical Center
Brian N. Finck
Brian N. Finck Washington University in St. Louis
Jay D. Horton
Jay D. Horton The University of Texas Southwestern Medical Center

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