Aly Karsan

Overview

Best Publications

• Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

  Timothy J. Ley;Christopher Miller;Li Ding;Benjamin J. Raphael

  6194
  Citations

• Apoptotic vascular endothelial cells become procoagulant

  Thomas Bombeli;Aly Karsan;Jonathan F. Tait;John M. Harlan

  858
  Citations

• Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype

  Daniel T Starczynowski;Florian Kuchenbauer;Bob Argiropoulos;Sandy Sung

  800
  Citations

• Lipopolysaccharide signaling in endothelial cells

  Shauna M Dauphinee;Aly Karsan

  767
  Citations

• Recent insights into the role of Notch signaling in tumorigenesis

  Kevin G. Leong;Aly Karsan

  697
  Citations

• Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin

  Kevin G. Leong;Kyle Niessen;Iva Kulic;Afshin Raouf

  582
  Citations

• Slug is a direct Notch target required for initiation of cardiac cushion cellularization

  Kyle Niessen;YangXin Fu;YangXin Fu;Linda Chang;Pamela A. Hoodless;Pamela A. Hoodless

  438
  Citations

• Notch Activation Results in Phenotypic and Functional Changes Consistent With Endothelial-to-Mesenchymal Transformation

  Michela Noseda;Graeme McLean;Kyle Niessen;Linda Chang

  352
  Citations

• Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers.

  Stephen Yip;Yaron S. Butterfield;Olena Morozova;Suganthi Chittaranjan

  335
  Citations

• Notch Signaling in Cardiac Development

  Kyle Niessen;Aly Karsan

  317
  Citations

• ENDOTHELIAL CELL DEATH INDUCED BY TUMOR NECROSIS FACTOR-ALPHA IS INHIBITED BY THE BCL-2 FAMILY MEMBER, A1

  Aly Karsan;Esther Yee;John M. Harlan

  294
  Citations

• Notch Activation Induces Endothelial Cell Cycle Arrest and Participates in Contact Inhibition: Role of p21Cip1 Repression

  Michela Noseda;Linda Chang;Graeme McLean;Jonathan E. Grim

  278
  Citations

• Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms.

  Aly Karsan;Esther Yee;Guy G. Poirier;Ping Zhou

  253
  Citations

• TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

  Detlef Haase;Kristen E Stevenson;Donna Neuberg;Jaroslaw P Maciejewski

  230
  Citations

• SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS

  Luca Malcovati;Kristen Stevenson;Elli Papaemmanuil;Donna Neuberg

  230
  Citations

• Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells

  Aly Karsan;Esther Yee;Kenneth Kaushansky;John M. Harlan

  223
  Citations

• Activated Notch4 Inhibits Angiogenesis: Role of β1-Integrin Activation

  Kevin G. Leong;Xiaolong Hu;Linheng Li;Michela Noseda

  215
  Citations

• Alpha-1-antitrypsin and a broad spectrum metalloprotease inhibitor, RS113456, have similar acute anti-inflammatory effects.

  Andrew Churg;Jin Dai;Katalin Zay;Aly Karsan

  210
  Citations

• Lipopolysaccharide induces the antiapoptotic molecules, A1 and A20, in microvascular endothelial cells.

  Xiaolong Hu;Xiaolong Hu;Esther Yee;Esther Yee;John M. Harlan;John M. Harlan;Fred Wong;Fred Wong

  209
  Citations

• Smooth Muscle α-Actin Is a Direct Target of Notch/CSL

  Michela Noseda;YangXin Fu;Kyle Niessen;Fred Wong

  207
  Citations