Her primary areas of study are Cell biology, Genetics, TGF beta signaling pathway, Signal transduction and Endoderm. She interconnects Immunology and Cellular differentiation in the investigation of issues within Cell biology. Her RNA-Seq, Contig, Transcriptome and Sequence assembly study in the realm of Genetics interacts with subjects such as Genomic library.
Her research integrates issues of Mothers against decapentaplegic homolog 2, Molecular biology, Phosphorylation and Smad2 Protein in her study of TGF beta signaling pathway. As a part of the same scientific family, she mostly works in the field of Signal transduction, focusing on Receptor and, on occasion, Orphan receptor. Her Endoderm research incorporates themes from Gastrulation and NODAL.
Pamela A. Hoodless spends much of her time researching Cell biology, Endoderm, Genetics, Transcription factor and Molecular biology. Her Cell biology research is multidisciplinary, incorporating elements of Embryonic stem cell, Definitive endoderm and Anatomy. The study incorporates disciplines such as NODAL, Gene expression, Notochord and Mesoderm in addition to Endoderm.
In general Genetics study, her work on Gene expression profiling, RNA-Seq and Transcriptome often relates to the realm of Genomic library, thereby connecting several areas of interest. Her study explores the link between Transcription factor and topics such as Cancer research that cross with problems in Cell growth, Carcinogenesis and Receptor. Her Signal transduction research is multidisciplinary, incorporating perspectives in Autocrine signalling, Bone morphogenetic protein and Phosphorylation.
Her main research concerns Cell biology, Endoderm, Embryonic stem cell, Hippo signaling pathway and Transcription factor. Pamela A. Hoodless has researched Cell biology in several fields, including Epigenomics, DNA methylation and Transcriptome. Pamela A. Hoodless has researched Endoderm in several fields, including Lineage, Hepatic stellate cell, Epiblast, Gastrulation and Embryo.
Her work in the fields of Embryonic stem cell, such as Mesoderm, intersects with other areas such as Population. Her work deals with themes such as Chromatin immunoprecipitation, Cancer research and Gene expression, which intersect with Hippo signaling pathway. Her studies deal with areas such as Histone, PI3K/AKT/mTOR pathway and Liver cell as well as Transcription factor.
Her primary scientific interests are in Transcription factor, MST1, Chromatin binding, Growth factor and CTGF. Her Transcription factor study focuses on Enhancer in particular. The study incorporates disciplines such as Cancer research and Downregulation and upregulation in addition to MST1.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
Kolja Eppert;Stephen W Scherer;Hilmi Ozcelik;Rosa Pirone.
Cell (1996)
De novo assembly and analysis of RNA-seq data
Gordon Robertson;Jacqueline Schein;Readman Chiu;Richard Corbett.
Nature Methods (2010)
MADR2 Is a Substrate of the TGFβ Receptor and Its Phosphorylation Is Required for Nuclear Accumulation and Signaling
Marina Macías-Silva;Shirin Abdollah;Pamela A Hoodless;Rosa Pirone.
Cell (1996)
MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways
Pamela A Hoodless;Theo Haerry;Shirin Abdollah;Mark Stapleton.
Cell (1996)
The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo
Daniel C. Weinstein;Ariel Ruiz i Altaba;William S. Chen;Pamela Hoodless.
Cell (1994)
Smad2 and Smad3 Positively and Negatively Regulate TGFβ-Dependent Transcription through the Forkhead DNA-Binding Protein FAST2
Etienne Labbé;Cristoforo Silvestri;Pamela A. Hoodless;Jeffrey L. Wrana.
Molecular Cell (1998)
Specific Activation of Smad1 Signaling Pathways by the BMP7 Type I Receptor, ALK2
Marina Macı́as-Silva;Pamela A. Hoodless;Shao Jun Tang;Manuel Buchwald.
Journal of Biological Chemistry (1998)
Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo.
W.Ross Waldrip;Elizabeth K Bikoff;Pamela A Hoodless;Jeffrey L Wrana.
Cell (1998)
Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst
Stephen A. Duncan;Katia Manova;William S. Chen;Pamela Hoodless.
Proceedings of the National Academy of Sciences of the United States of America (1994)
Slug is a direct Notch target required for initiation of cardiac cushion cellularization
Kyle Niessen;YangXin Fu;YangXin Fu;Linda Chang;Pamela A. Hoodless;Pamela A. Hoodless.
Journal of Cell Biology (2008)
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