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Molecular Biology

D-Index
73
Citations
15850
World Ranking
1293
National Ranking
34

Overview

Joel P. Mackay is affiliated with the University of Sydney in Australia. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a focused expertise within Molecular Biology, Genetics, Infectious Diseases, Immunology, and Oncology.

Their main research topics include:

  • Genomics and Chromatin Dynamics
  • Protein Degradation and Inhibitors
  • RNA modifications and cancer
  • Peptidase Inhibition and Analysis
  • Histone Deacetylase Inhibitors Research
  • SARS-CoV-2 and COVID-19 Research
  • RNA Research and Splicing

Joel P. Mackay has contributed to numerous publications across several prominent venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Journal of Biological Chemistry
  • Zenodo (CERN European Organization for Nuclear Research)

Some of their recent papers are:

  • A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection, 2021, npj Vaccines
  • Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display, 2021, ACS Central Science
  • CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation, 2020, Nature Communications
  • Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein-protein interactions in the human cell, 2023, Proceedings of the National Academy of Sciences
  • Cyclic peptides can engage a single binding pocket through highly divergent modes, 2020, Proceedings of the National Academy of Sciences

In collaboration, Joel P. Mackay frequently works with several coauthors, including:

  • Jason K. K. Low
  • Karishma Patel
  • Richard J. Payne
  • Charlotte Franck
  • Alexander Norman

Best Publications

  • Zinc fingers are sticking together

    Joel P. Mackay;Merlin Crossley

  • Sticky fingers: zinc-fingers as protein-recognition motifs

    Roland Gamsjaeger;Chu Kong Liew;Fionna E. Loughlin;Merlin Crossley

  • Mutations in Cardiac T-Box Factor Gene TBX20 Are Associated with Diverse Cardiac Pathologies, Including Defects of Septation and Valvulogenesis and Cardiomyopathy

    Edwin P. Kirk;Edwin P. Kirk;Edwin P. Kirk;Margaret Sunde;Mauro W. Costa;Mauro W. Costa;Scott A Rankin

  • Cardiac hypertrophy and histone deacetylase–dependent transcriptional repression mediated by the atypical homeodomain protein Hop

    Hyun Kook;John J. Lepore;Aaron D. Gitler;Min Min Lu

  • Hop is an unusual homeobox gene that modulates cardiac development.

    Fabian Chen;Hyun Kook;Rita Milewski;Aaron D. Gitler

  • Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: the GATA-1:FOG complex.

    John D Crispino;John D Crispino;Maya B Lodish;Maya B Lodish;Joel P MacKay;Stuart H Orkin;Stuart H Orkin

  • Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

    Archa H. Fox;Chu Liew;Melissa Holmes;Kasper Kowalski

  • Structural basis for rodlet assembly in fungal hydrophobins

    Ahy Kwan;RD Winefield;M Sunde;JM Matthews

  • Structural analysis of hydrophobins

    Margaret Sunde;Ann H.Y. Kwan;Matthew D. Templeton;Ross E. Beever

  • Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice

    Arne Ittner;Sook Wern Chua;Josefine Bertz;Alexander Volkerling

  • Macromolecular NMR spectroscopy for the non-spectroscopist

    Ann H. Kwan;Mehdi Mobli;Paul R. Gooley;Glenn F. King

  • Glycopeptide antibiotic activity and the possible role of dimerization : A model for biological signaling

    Joel P. Mackay;Ute Gerhard;Daniel A. Beauregard;Dudley H. Williams

  • Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes

    Janine M. Lamonica;Wulan Deng;Stephan Kadauke;Amy E. Campbell

  • Toward an estimation of binding constants in aqueous solution: studies of associations of vancomycin group antibiotics.

    Dudley H. Williams;Mark S. Searle;Joel P. Mackay;Ute Gerhard

  • The role of the sugar and chlorine substituents in the dimerization of vancomycin antibiotics

    Ute Gerhard;Joel P. Mackay;Rachael A. Maplestone;Dudley H. Williams

  • Binding of the CHD4 PHD2 Finger to Histone H3 is Modulated by Covalent Modifications

    Catherine A. Musselman;Robyn E. Mansfield;Adam L. Garske;Foteini Davrazou

  • dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression.

    Henriette O'Geen;Chonghua Ren;Chonghua Ren;Charles M Nicolet;Andrew A Perez

  • Loss of α-hemoglobin–stabilizing protein impairs erythropoiesis and exacerbates β-thalassemia

    Yi Kong;Suiping Zhou;Anthony J. Kihm;Anthony J. Kihm;Anne M. Katein

  • Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9

    Robyn E. Mansfield;Catherine A. Musselman;Ann H. Kwan;Samuel S. Oliver

  • Dissection of the contributions toward dimerization of glycopeptide antibiotics

    Joel P. Mackay;Ute Gerhard;Daniel A. Beauregard;Rachael A. Maplestone

Frequent Co-Authors

Merlin Crossley
Merlin Crossley University of New South Wales
Glenn F. King
Glenn F. King University of Queensland
Margaret Sunde
Margaret Sunde University of Sydney
Mitchell J. Weiss
Mitchell J. Weiss St. Jude Children's Research Hospital
Gerd A. Blobel
Gerd A. Blobel Children's Hospital of Philadelphia
David J. Segal
David J. Segal University of California, Davis
Richard J. Payne
Richard J. Payne University of Sydney
Jane E. Visvader
Jane E. Visvader Walter and Eliza Hall Institute of Medical Research
Richard P. Harvey
Richard P. Harvey Victor Chang Cardiac Research Institute
Dudley H. Williams
Dudley H. Williams University of Cambridge

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