What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Biochemistry, Protein structure, Genetics, Zinc finger and Plasma protein binding.
Biochemistry connects with themes related to Biophysics in his study.
The concepts of his Protein structure study are interwoven with issues in Hydrophobin, Stereochemistry and Fungal protein.
Joel P. Mackay combines subjects such as DNA-binding protein, SIAH2, DNA ligase, Cell biology and Composite material with his study of Zinc finger.
Joel P. Mackay has included themes like Affinities, Nuclear protein and Computational biology in his DNA-binding protein study.
His Plasma protein binding study incorporates themes from SIAH1, Electron transport chain and Ubiquitin.
His most cited work include:
- Zinc fingers are sticking together (382 citations)
- Sticky fingers: zinc-fingers as protein-recognition motifs (329 citations)
- Cardiac hypertrophy and histone deacetylase–dependent transcriptional repression mediated by the atypical homeodomain protein Hop (277 citations)
What are the main themes of his work throughout his whole career to date?
Joel P. Mackay focuses on Cell biology, Biochemistry, Zinc finger, Genetics and Protein structure.
His study in Cell biology is interdisciplinary in nature, drawing from both Transcription factor, Chromatin, Histone, Nucleosome and Molecular biology.
Joel P. Mackay focuses mostly in the field of Biochemistry, narrowing it down to matters related to Biophysics and, in some cases, Binding site.
In his research, Computational biology is intimately related to RNA, which falls under the overarching field of Zinc finger.
His biological study spans a wide range of topics, including Crystallography, Nuclear magnetic resonance spectroscopy, Stereochemistry and Protein–protein interaction.
His work carried out in the field of LIM domain brings together such families of science as Binding domain and LMO2.
He most often published in these fields:
- Cell biology (25.98%)
- Biochemistry (24.80%)
- Zinc finger (21.65%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (25.98%)
- Nucleosome (9.06%)
- Mi-2/NuRD complex (8.27%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cell biology, Nucleosome, Mi-2/NuRD complex, Chromatin and Bromodomain.
His Chromatin study integrates concerns from other disciplines, such as Protein structure, Histone, Epigenetics and Protein domain.
His Protein structure research is multidisciplinary, relying on both Steric effects, Plasma protein binding, Hydrogen bond and Protein–protein interaction.
His studies in Bromodomain integrate themes in fields like Transcription factor, Computational biology and Binding pocket.
In his study, Zinc finger is inextricably linked to Sequence, which falls within the broad field of Fusion protein.
The DNA study combines topics in areas such as Biophysics and Binding site.
Between 2017 and 2021, his most popular works were:
- PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex. (19 citations)
- A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence. (17 citations)
- The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators (17 citations)
In his most recent research, the most cited papers focused on:
Joel P. Mackay mainly investigates Genetics, Cell biology, Mi-2/NuRD complex, Histone and Nucleosome.
His work on CRISPR, Point mutation and Zinc finger as part of general Genetics study is frequently connected to Human genome, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His research integrates issues of Chemokine, Sulfation and Native chemical ligation in his study of Cell biology.
His research in Histone intersects with topics in Chromatin, Plasma protein binding, Protein structure and Protein–protein interaction.
As a member of one scientific family, he mostly works in the field of Nucleosome, focusing on Chromodomain and, on occasion, Function.
His Chromatin remodeling study improves the overall literature in Transcription factor.
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