Ikuko Nagatsu

Overview

Best Publications

• Use of high concentrations of glutaraldehyde for immunocytochemistry of transmitter-synthesizing enzymes in the central nervous system

  T. Kosaka;I. Nagatsu;J.-Y. Wu;K. Hama

  338
  Citations

• Targeted Disruption of the Tyrosine Hydroxylase Locus Results in Severe Catecholamine Depletion and Perinatal Lethality in Mice

  Kazuto Kobayashi;Shinji Morita;Hirohide Sawada;Tomoko Mizuguchi

  311
  Citations

• Chemically defined neuron groups and their subpopulations in the glomerular layer of the rat main olfactory bulb

  Katsuko Kosaka;Yusuke Aika;Kazunori Toida;Claus W. Heizmann

  298
  Citations

• Triple Transduction with Adeno-Associated Virus Vectors Expressing Tyrosine Hydroxylase, Aromatic-L-Amino-Acid Decarboxylase, and GTP Cyclohydrolase I for Gene Therapy of Parkinson's Disease

  Yang Shen;Shin-Ichi Muramatsu;Kunihiko Ikeguchi;Ken-Ichi Fujimoto

  287
  Citations

• Coexistence of immunoreactivities for glutamate decar☐ylase and tyrosine hydroxylase in some neurons in the periglomerular region of the rat main olfactory bulb: possible coexistence of gamma-aminobutyric acid (GABA) and dopamine

  Toshio Kosaka;Yoshihiro Hataguchi;Kiyoshi Hama;Ikuko Nagatsu

  270
  Citations

• Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes

  Shin-Ichi Muramatsu;Ken-Ichi Fujimoto;Kunihiko Ikeguchi;Nami Shizuma

  244
  Citations

• Migration of dopaminergic neurons in the embryonic mesencephalon of mice.

  Hitoshi Kawano;Kyoji Ohyama;Koki Kawamura;Ikuko Nagatsu

  225
  Citations

• Immunohistochemical evidence that central serotonin neurons produce dopamine from exogenous L-DOPA in the rat, with reference to the involvement of aromatic L-amino acid decarboxylase.

  Ryohachi Arai;Nobuyuki Karasawa;Michel Geffard;Toshiharu Nagatsu

  221
  Citations

• Behavioral Recovery in 6-Hydroxydopamine-Lesioned Rats by Cotransduction of Striatum with Tyrosine Hydroxylase and Aromatic l-Amino Acid Decarboxylase Genes Using Two Separate Adeno-Associated Virus Vectors

  Dong-Shen Fan;Matsuo Ogawa;Ken-Ichi Fujimoto;Kunihiko Ikeguchi

  209
  Citations

• Reduced mastication stimulates impairment of spatial memory and degeneration of hippocampal neurons in aged SAMP8 mice.

  Minoru Onozuka;Kazuko Watanabe;Seyed M Mirbod;Satoru Ozono

  209
  Citations

• Tyrosine hydroxylase-like immunoreactive neurons in the striatum of the rat.

  Yuzuru Tashiro;Tetsuo Sugimoto;Toshiaki Hattori;Yoshihiko Uemura

  204
  Citations

• l-DOPA is converted to dopamine in serotonergic fibers of the striatum of the rat: a double-labeling immunofluorescence study

  Unknown

  191
  Citations

• Immunohistochemical demonstration of glutaminase in catecholaminergic and serotoninergic neurons of rat brain.

  Takeshi Kaneko;Haruhiko Akiyama;Ikuko Nagatsu;Noboru Mizuno

  189
  Citations

• Requirement of neuropilin 1-mediated Sema3A signals in patterning of the sympathetic nervous system.

  Takahiko Kawasaki;Yoko Bekku;Fumikazu Suto;Takashi Kitsukawa

  188
  Citations

• Successive cleavage of N-terminal Arg1-Pro2 and Lys3-Pro4 from substance P but no release of Arg1-Pro2 from bradykinin, by X-Pro dipeptidyl-aminopeptidase

  Takeshi Kato;Toshiharu Nagatsu;Katsuhiko Fukasawa;Minoru Harada

  180
  Citations

• Biopterin in human brain and urine from controls and parkinsonian patients: Application of a new radioimmunoassay

  Toshiharu Nagatsu;Tokio Yamaguchi;Takeshi Kato;Takashi Sugimoto

  164
  Citations

• Aromatic L-amino acid decarboxylase-immunoreactive neurons in and around the cerebrospinal fluid-contacting neurons of the central canal do not contain dopamine or serotonin in the mouse and rat spinal cord.

  Ikuko Nagatsu;Masao Sakai;Masami Yoshida;Toshiharu Nagatsu

  153
  Citations

• Tissue-specific and high-level expression of the human tyrosine hydroxylase gene in transgenic mice

  Norio Kaneda;Toshikuni Sasaoka;Kazuto Kobayashi;Kazutoshi Kiuchi

  150
  Citations

• An aspect of the organization of the GABAergic system in the rat main olfactory bulb: laminar distribution of immunohistochemically defined subpopulations of GABAergic neurons.

  Toshio Kosaka;Katsuko Kosaka;Claus W. Heizmann;Ikuko Nagatsu

  149
  Citations

• IMMUNOFLUORESCENT STUDIES ON THE LOCALIZATION OF TYROSINE HYDROXYLASE AND DOPAMINE-β-HYDROXYLASE IN THE MES-, DI-, AND TELENCEPHALON OF THE RAT USING UNPERFUSED FRESH FROZEN SECTIONS

  Ikuko Nagatsu;Shinobu Inagaki;Yukari Kondo;Nobuyuki Karasawa

  142
  Citations

• Impairment of spatial memory and changes in astroglial responsiveness following loss of molar teeth in aged SAMP8 mice.

  Minoru Onozuka;Kazuko Watanabe;Sachio Nagasaki;Yifa Jiang

  137
  Citations

• Catecholaminergic neurons containing GABA-like and/or glutamic acid decarboxylase-like immunoreactivities in various brain regions of the rat

  Unknown

  112
  Citations