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Genetics

D-Index
71
Citations
14953
World Ranking
2218
National Ranking
278

Overview

Nabeel A. Affara is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple fields including Medicine, Nursing, and Biochemistry, Genetics and Molecular Biology. The subfields in which they have contributed include Nutrition and Dietetics, Pediatrics, Perinatology and Child Health, Genetics, Molecular Biology, and Safety Research.

Their work covers a range of scientific topics, notably Child Nutrition and Water Access, Birth, Development, and Health, Poverty, Education, and Child Welfare, Obesity, Physical Activity, Diet, Genetic and phenotypic traits in livestock, Genetic Mapping and Diversity in Plants and Animals, and Genomics and Phylogenetic Studies.

Affara has published research in various venues. These include GigaScience, Gates Open Research, FASEB BioAdvances, Frontiers in Endocrinology, and the American Journal of Physical Anthropology. Their five recent papers are:

  • An improved pig reference genome sequence to enable pig genetics and genomics research, 2020, GigaScience
  • Identification of nutritionally modifiable hormonal and epigenetic drivers of positive and negative growth deviance in rural African fetuses and infants: Project protocol and cohort description, 2020, Gates Open Research
  • Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach of genomic DNA, 2021, FASEB BioAdvances
  • Timing of the Infancy-Childhood Growth Transition in Rural Gambia, 2020, Frontiers in Endocrinology
  • A Novel method for the identification and quantification of weight faltering, 2021, American Journal of Physical Anthropology

Frequent collaborators include David B. Dunger, Sophie E. Moore, Ken K. Ong, Andrew M. Prentice, and Robin M. Bernstein.

Best Publications

  • The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the 'termination' codon, TGA.

    I Chambers;J Frampton;P Goldfarb;N Affara

  • Design of a High Density SNP Genotyping Assay in the Pig Using SNPs Identified and Characterized by Next Generation Sequencing Technology

    António M Ramos;Richard P M A Crooijmans;Nabeel A Affara;Andreia J. Amaral

  • Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan.

    Berton Zbar;Takeshi Kishida;Fan Chen;Laura Schmidt

  • An improved pig reference genome sequence to enable pig genetics and genomics research

    Amanda Warr;Nabeel Affara;Bronwen Aken;Hamid Beiki

  • Somatic mutations of the von Hippel — Lindau disease tumour suppressor gene in non-familial clear cell renal carcinoma

    Keith Foster;Amanda Prowse;Anke van den Berg;Stewart Fleming

  • Karyomapping: a universal method for genome wide analysis of genetic disease based on mapping crossovers between parental haplotypes

    Alan H Handyside;Gary L Harton;Brian Mariani;Alan R Thornhill

  • Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis.

    Steven C. Clifford;Amanda H. Prowse;Nabeel A. Affara;Charles H. C. M. Buys

  • Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene

    Graeme M. Brown;Robert A. Furlong;Carole A. Sargent;Robert P. Erickson

  • Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors.

    A H Prowse;A R Webster;F M Richards;S Richard

  • Divergent outcomes of intrachromosomal recombination on the human Y chromosome: male infertility and recurrent polymorphism

    Patricia Blanco;Maria Shlumukova;Carole A Sargent;Mark A Jobling

  • Report of the Second International Workshop on Y Chromosome Mapping 1995.

    N. Affara;C. Bishop;W. Brown;H. Cooke

  • Localization of DNA sequences required for human centromere function through an analysis of rearranged Y chromosomes.

    Chris Tyler-Smith;Rebecca J. Oakey;Zoia Larin;Richard B. Fisher;Richard B. Fisher

  • Complete and partial XY sex reversal associated with terminal deletion of 10q: Report of 2 cases and literature review

    A. O. M. Wilkie;F. M. Campbell;P. Daubeney;D. B. Grant

  • Sperm-Induced Modification of the Oviductal Gene Expression Profile After Natural Insemination in Mice

    Alireza Fazeli;Nabeel A. Affara;Michael Hubank;William V. Holt

  • The Drosophila Developmental Gene Fat Facets Has a Human Homologue in Xp11.4 Which Escapes X-inactivation and Has Related Sequences on Yq11.2

    Michael H. Jones;Robert A. Furlong;Heather Burkin;I. Jennifer Chalmers

  • A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse.

    Julie Cocquet;Peter J. I. Ellis;Shantha K. Mahadevaiah;Nabeel A. Affara

  • Molecular genetic investigations of the mechanism of tumourigenesis in von Hippel-Lindau disease: analysis of allele loss in VHL tumours.

    Paul A. Crossey;Keith Foster;Frances M. Richards;Maude E. Phipps

  • The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis.

    Julie Cocquet;Peter J. I. Ellis;Yasuhiro Yamauchi;Shantha K. Mahadevaiah

  • Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: a study of a unique resource in the Gambia

    Batbayar Khulan;Wendy N. Cooper;Benjamin M. Skinner;Julien Bauer

  • Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain.

    Patricia Blanco;Carole A. Sargent;Catherine A. Boucher;Michael Mitchell

Frequent Co-Authors

Malcolm A. Ferguson-Smith
Malcolm A. Ferguson-Smith University of Cambridge
Eamonn R. Maher
Eamonn R. Maher University of Cambridge
Darren K. Griffin
Darren K. Griffin University of Kent
David B. Dunger
David B. Dunger University of Cambridge
Michael J. Mitchell
Michael J. Mitchell University of Pennsylvania
John R.W. Yates
John R.W. Yates University of Cambridge
Paul S. Burgoyne
Paul S. Burgoyne Medical Research Council
Andrew M. Prentice
Andrew M. Prentice London School of Hygiene & Tropical Medicine
Berton Zbar
Berton Zbar National Institutes of Health
Michael I. Lerman
Michael I. Lerman National Institutes of Health

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