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Genetics

D-Index
68
Citations
15927
World Ranking
2435
National Ranking
308

Overview

Paul S. Burgoyne was affiliated with the Medical Research Council in the United Kingdom. Their research spanned several areas within medicine and engineering, with a focus on biomedical applications.

Their work contributed to multiple fields including:

  • Medicine
  • Engineering

Within these, the scientist explored subfields such as:

  • Biomedical Engineering
  • Oncology
  • Immunology
  • Infectious Diseases
  • Molecular Biology

The main topics addressed in their research included:

  • CAR-T cell therapy research
  • 3D Printing in Biomedical Research
  • Pancreatic function and diabetes
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Immunotherapy and Immune Responses
  • Microfluidic and Bio-sensing Technologies

Paul S. Burgoyne coauthored work frequently with several researchers. The most frequent collaborators were:

  • Alasdair R. Fraser
  • John Campbell
  • Gerard J. Graham
  • Rachel Cooper
  • Thomas Carvell

The scientist published in a variety of journals, including:

  • Journal of Leukocyte Biology
  • Science Translational Medicine
  • Frontiers in Immunology
  • American Journal of Transplantation
  • Journal of The Royal Society Interface

Among their recent papers were:

  • "Human umbilical cord perivascular cells improve human pancreatic islet transplant function by increasing vascularization," 2020, Science Translational Medicine
  • "Rapid GMP-Compliant Expansion of SARS-CoV-2-Specific T Cells From Convalescent Donors for Use as an Allogeneic Cell Therapy for COVID-19," 2021, Frontiers in Immunology
  • "Fibroblast growth factor 7 releasing particles enhance islet engraftment and improve metabolic control following islet transplantation in mice with diabetes," 2021, American Journal of Transplantation
  • "CCR7+ dendritic cells sorted by binding of CCL19 show enhanced Ag-presenting capacity and antitumor potency," 2021, Journal of Leukocyte Biology
  • "Human leucocytes processed by fast-rate inertial microfluidics retain conventional functional characteristics," 2024, Journal of The Royal Society Interface

Best Publications

  • Recombinational DNA double-strand breaks in mice precede synapsis

    Shantha K. Mahadevaiah;James M.A. Turner;Frédéric Baudat;Emmy P. Rogakou

  • H2AX Is Required for Chromatin Remodeling and Inactivation of Sex Chromosomes in Male Mouse Meiosis

    Oscar Fernandez-Capetillo;Shantha K. Mahadevaiah;Arkady Celeste;Peter J. Romanienko

  • Dax1 antagonizes Sry action in mammalian sex determination

    Amanda Swain;Veronica Narvaez;Veronica Narvaez;Paul Burgoyne;Giovanna Camerino

  • A Model System for Study of Sex Chromosome Effects on Sexually Dimorphic Neural and Behavioral Traits

    Geert J. De Vries;Emilie F. Rissman;Richard B. Simerly;Liang-Yo Yang

  • Silencing of unsynapsed meiotic chromosomes in the mouse.

    James M A Turner;Shantha K Mahadevaiah;Oscar Fernandez-Capetillo;André Nussenzweig

  • Genetic homology and crossing over in the X and Y chromosomes of Mammals.

    Paul S. Burgoyne

  • The consequences of asynapsis for mammalian meiosis

    Paul S Burgoyne;Shantha K Mahadevaiah;James M A Turner

  • BRCA1, Histone H2AX Phosphorylation, and Male Meiotic Sex Chromosome Inactivation

    James M.A. Turner;Olga Aprelikova;Xiaoling Xu;Ruihong Wang

  • Pachytene Asynapsis Drives Meiotic Sex Chromosome Inactivation and Leads to Substantial Postmeiotic Repression in Spermatids

    James M.A. Turner;Shantha K. Mahadevaiah;Peter J.I. Ellis;Michael J. Mitchell

  • Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals.

    Ian G. Cowell;Rebecca Aucott;Shantha K. Mahadevaiah;Paul S. Burgoyne

  • Evidence that meiotic sex chromosome inactivation is essential for male fertility.

    Hélène Royo;Grzegorz Polikiewicz;Shantha K. Mahadevaiah;Haydn Prosser

  • Mouse Homologues of the Human AZF Candidate Gene RBM Are Expressed in Spermatogonia and Spermatids, and Map to a Y Chromosome Deletion Interval Associated with a High Incidence of Sperm Abnormalities

    Shantha K. Mahadevaiah;Teresa Odorisio;David J. Elliott;Áine Rattigan

  • Heterochromatin and tri-methylated lysine 20 of histone H4 in animals.

    Niki Kourmouli;Peter Jeppesen;Shantha Mahadevhaiah;Paul Burgoyne

  • The meiotic checkpoint monitoring synapsis eliminates spermatocytes via p53-independent apoptosis

    Teresa Odorisio;Tristan A. Rodriguez;Edward P. Evans;Alan R. Clarke

  • Sex differences in sex chromosome gene expression in mouse brain

    Jun Xu;Paul S. Burgoyne;Arthur P. Arnold

  • Sex chromosome complement and gonadal sex influence aggressive and parental behaviors in mice.

    Jessica D. Gatewood;Aileen Wills;Savera Shetty;Jun Xu

  • Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice

    William Davies;Anthony Roger Isles;Rachel Smith;Delicia Karunadasa

  • Fertility in mice requires X-Y pairing and a Y-chromosomal "spermiogenesis" gene mapping to the long arm.

    Paul S. Burgoyne;Shantha K. Mahadevaiah;Maxine J. Sutcliffe;Stephen J. Palmer

  • Surveillance of different recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical developmental stage.

    Marco Barchi;Shantha Mahadevaiah;Monica Di Giacomo;Frédéric Baudat

  • Cell-autonomous action of the testis-determining gene: Sertoli cells are exclusively XY in XX—XY chimaeric mouse testes

    P.S. Burgoyne;M. Buehr;P. Koopman;J. Rossant

Frequent Co-Authors

Michael J. Mitchell
Michael J. Mitchell University of Pennsylvania
David J. Elliott
David J. Elliott Newcastle University
Nabeel A. Affara
Nabeel A. Affara University of Cambridge
Dirk G. de Rooij
Dirk G. de Rooij Utrecht University
Arthur P. Arnold
Arthur P. Arnold University of California, Los Angeles
Lawrence Stephen Wilkinson
Lawrence Stephen Wilkinson Cardiff University
Robin Lovell-Badge
Robin Lovell-Badge The Francis Crick Institute
Trevor Humby
Trevor Humby Cardiff University
Daniel Vaiman
Daniel Vaiman Université Paris Cité
Prim B. Singh
Prim B. Singh Nazarbayev University

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