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Biology and Biochemistry

D-Index
56
Citations
13257
World Ranking
14293
National Ranking
551

Overview

Yves Bourne is affiliated with Aix-Marseille University in France and has contributed to multiple research areas primarily within Biochemistry, Genetics, and Molecular Biology. Their work extensively covers Molecular Biology, Cell Biology, Genetics, Pharmacology, and Cognitive Neuroscience.

The scientist's research topics include:

  • Cellular transport and secretion
  • Glycosylation and Glycoproteins Research
  • Autism Spectrum Disorder Research
  • Genetics and Neurodevelopmental Disorders
  • Genetics, Aging, and Longevity in Model Organisms
  • Cellular Mechanics and Interactions
  • Pharmacogenetics and Drug Metabolism

Yves Bourne has published several recent papers, notable among these are:

  • The neuroligins and the synaptic pathway in Autism Spectrum Disorder, 2020, Neuroscience & Biobehavioral Reviews
  • The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1, 2020, Journal of Biological Chemistry
  • Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis, 2022, FEBS Journal
  • Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS, 2022, Structure
  • Comparative mapping of selected structural determinants on the extracellular domains of cholinesterase-like cell-adhesion molecules, 2020, Neuropharmacology

The frequent co-authors listed in association with Yves Bourne's work include:

  • P. Marchot
  • Laura Trobiani
  • Maria Meringolo
  • Tamara Diamanti
  • Giuseppina Martella

Their studies are frequently published in venues such as:

  • Journal of Biological Chemistry
  • Neuroscience & Biobehavioral Reviews
  • FEBS Journal
  • Structure
  • Neuropharmacology

Best Publications

  • Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.

    Scott B Hansen;Gerlind Sulzenbacher;Tom Huxford;Pascale Marchot

  • Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism.

    Christopher D Putnam;Andrew S Arvai;Yves Bourne;John A Tainer

  • Glycoside hydrolases and glycosyltransferases: families and functional modules.

    Yves Bourne;Bernard Henrissat

  • Acetylcholinesterase Inhibition by Fasciculin: Crystal Structure of the Complex

    Yves Bourne;Yves Bourne;Palmer Taylor;Pascale Marchot

  • Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site

    Yves Bourne;Palmer Taylor;Zoran Radić;Pascale Marchot

  • Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation.

    Yves Bourne;Hartmuth C. Kolb;Zoran Radić;K. Barry Sharpless

  • Crystal structure of a Cbtx–AChBP complex reveals essential interactions between snake α-neurotoxins and nicotinic receptors

    Yves Bourne;Todd T Talley;Scott B Hansen;Palmer Taylor

  • Bacterial glycosidases for the production of universal red blood cells

    Qiyong P Liu;Gerlind Sulzenbacher;Huaiping Yuan;Eric P Bennett

  • Crystal structures of the bovine β4galactosyltransferase catalytic domain and its complex with uridine diphosphogalactose

    Louis Noél Gastinel;Christian Cambillau;Yves Bourne

  • Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1.

    Yves Bourne;Mark H Watson;Michael J Hickey;William Holmes

  • ESTHER, the database of the α/β-hydrolase fold superfamily of proteins: tools to explore diversity of functions

    Nicolas Lenfant;Thierry Hotelier;Eric Velluet;Yves Bourne

  • Crosslinking of mammalian lectin (galectin-1) by complex biantennary saccharides.

    Yves Bourne;Barbara Bolgiano;Der-Ing Liao;Gérard Strecker

  • Crystal structure of the bifunctional N-acetylglucosamine 1-phosphate uridyltransferase from Escherichia coli: a paradigm for the related pyrophosphorylase superfamily

    Kieron Brown;Fredérique Pompeo;Suzanne Dixon;Dominique Mengin‐Lecreulx

  • Immunocytochemical localization and crystal structure of human frequenin (neuronal calcium sensor 1).

    Yves Bourne;Jens Dannenberg;Verena Pollmann;Pascale Marchot

  • Structure of human lysosomal acid α-glucosidase–a guide for the treatment of Pompe disease

    Véronique Roig-Zamboni;Beatrice Cobucci-Ponzano;Roberta Iacono;Maria Carmina Ferrara

  • Conformational flexibility of the acetylcholinesterase tetramer suggested by x-ray crystallography.

    Yves Bourne;Jacques Grassi;Pierre E. Bougis;Pascale Marchot

  • High-throughput automated refolding screening of inclusion bodies.

    Renaud Vincentelli;Stéphane Canaan;Stéphane Canaan;Valérie Campanacci;Christel Valencia

  • Mannose-binding plant lectins: different structural scaffolds for a common sugar-recognition process.

    Annick Barre;Yves Bourne;Els J.M. Van Damme;Willy J. Peumans

  • Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture.

    Caroline Peneff;Paul Ferrari;Véronique Charrier;Yvette Taburet

  • Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor

    Ryan E Hibbs;Gerlind Sulzenbacher;Jianxin Shi;Todd T Talley

Frequent Co-Authors

Palmer Taylor
Palmer Taylor University of California, San Diego
Pierre Rougé
Pierre Rougé Paul Sabatier University
Christian Cambillau
Christian Cambillau Centre national de la recherche scientifique, CNRS
Bernard Henrissat
Bernard Henrissat Technical University of Denmark
Willy J. Peumans
Willy J. Peumans Ghent University
Annick Barre
Annick Barre Paul Sabatier University
Allan D. Kirk
Allan D. Kirk Duke University
Jordi Molgó
Jordi Molgó Centre national de la recherche scientifique, CNRS
Hugues Lortat-Jacob
Hugues Lortat-Jacob Grenoble Alpes University
Dominique Mengin-Lecreulx
Dominique Mengin-Lecreulx University of Paris-Saclay

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