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Richard M. W. Hoetelmans

Richard M. W. Hoetelmans

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
8237
World Ranking
15830
National Ranking
6579

Overview

Richard M. W. Hoetelmans is affiliated with Tibotec in the United States and has contributed to the field of Medicine, with a primary focus on Infectious Diseases. Their work encompasses multiple subfields including Epidemiology, Public Health, Environmental and Occupational Health, Virology, and Psychiatry and Mental Health.

Their research topics cover a range of areas related to viral infections and immunology. Key topics include:

  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Influenza Virus Research Studies
  • Mosquito-borne diseases and control
  • Malaria Research and Control
  • Viral Infections and Vectors
  • HIV Research and Treatment

Hoetelmans has collaborated frequently with several coauthors, indicating ongoing research partnerships. Frequent coauthors include:

  • Anna Dari
  • Muriel Boulton
  • Juan José Pérez Ruixo
  • Stephen J. Balevic
  • Sam Bozzette

The scientist's work has been published in a variety of journals. Frequent publication venues include:

  • The Journal of Clinical Pharmacology
  • Clinical Infectious Diseases
  • Clinical Pharmacology & Therapeutics
  • AIDS
  • The International Journal of Tuberculosis and Lung Disease

Recent papers authored or coauthored by Hoetelmans cover clinical and pharmacological aspects of infectious diseases and vaccine research. These include:

  • Safety, Tolerability, and Pharmacokinetics of JNJ-1802, a Pan-serotype Dengue Direct Antiviral Small Molecule, in a Phase 1, Double-Blind, Randomized, Dose-Escalation Study in Healthy Volunteers (2023), published in Clinical Infectious Diseases
  • Quantifying Antibody Persistence After a Single Dose of COVID-19 Vaccine Ad26.COV2.S in Humans Using a Mechanistic Modeling and Simulation Approach (2022), published in Clinical Pharmacology & Therapeutics
  • Zidovudine and lamivudine reach higher concentrations in ventricular than in lumbar human cerebrospinal fluid (2020), published in AIDS
  • Infliximab Concentrations in Participants with Moderate to Severe COVID-19 (2023), published in The Journal of Clinical Pharmacology
  • Mechanistic Model Describing the Time Course of Humoral Immunity Following Ad26.COV2.S Vaccination in Non-Human Primates (2023), published in Journal of Pharmacology and Experimental Therapeutics

Best Publications

  • Limited patient adherence to highly active antiretroviral therapy for HIV-1 infection in an observational cohort study.

    Pythia T. Nieuwkerk;Mirjam A. G. Sprangers;David M. Burger;Richard M. W. Hoetelmans

  • High exposure to nevirapine in plasma is associated with an improved virological response in HIV-1-infected individuals.

    Agnes I. Veldkamp;Gerrit J. Weverling;Joep M. A. Lange;Julio S. G. Montaner

  • Antiretroviral drugs and the central nervous system

    Roelien H. Enting;Richard M.w. Hoetelmans;Joep M.a. Lange;David M. Burger

  • Therapeutic drug monitoring in HIV infection: current status and future directions.

    David J. Back;Giorgio Gatti;Courtney Fletcher;Rodolphe Garaffo

  • Cerebrospinal-fluid HIV-1 RNA and drug concentrations after treatment with lamivudine plus zidovudine or stavudine.

    Norbert A Foudraine;Richard Mw Hoetelmans;Joep Ma Lange;Frank de Wolf

  • Drug interaction between St John's wort and nevirapine

    M M de Maat;R M Hoetelmans;E C van Gorp

  • Darunavir: pharmacokinetics and drug interactions.

    David Back;Vanitha Sekar;Richard M W Hoetelmans

  • P-glycoprotein limits oral availability, brain, and fetal penetration of saquinavir even with high doses of ritonavir.

    Maarten T. Huisman;Johan W. Smit;Hugh R. Wiltshire;Richard M. W. Hoetelmans

  • Low plasma concentrations of indinavir are related to virological treatment failure in HIV-1-infected patients on indinavir-containing triple therapy.

    David M Burger;Richard Mw Hoetelmans;Patricia Wh Hugen;Jan W Mulder

  • The steady-state pharmacokinetics of nevirapine during once daily and twice daily dosing in HIV-1-infected individuals.

    Rolf P. G. van Heeswijk;Agnes I. Veldkamp;Jan W. Mulder;Pieter L. Meenhorst

  • The effect of plasma drug concentrations on HIV-1 clearance rate during quadruple drug therapy

    R. M. W. Hoetelmans;M. H. E. Reijers;G. J. Weverling;R. W. Ten Kate

  • Short-term antiviral activity of TMC278--a novel NNRTI--in treatment-naive HIV-1-infected subjects.

    Frank Goebel;Alexy Yakovlev;Anton L Pozniak;Elena Vinogradova

  • Efficacy of Cerebrospinal Fluid (CSF)–Penetrating Antiretroviral Drugs against HIV in the Neurological Compartment: Different Patterns of Phenotypic Resistance in CSF and Plasma

    Andrea Antinori;Carlo Federico Perno;Maria Letizia Giancola;Federica Forbici

  • Clinical pharmacokinetics and pharmacodynamics of etravirine.

    Monika Schöller-Gyüre;Thomas N. Kakuda;Araz Raoof;Goedele De Smedt

  • Alternative multidrug regimen provides improved suppression of HIV-1 replication over triple therapy

    Gerrit J. Weverling;Joep M.A. Lange;Suzanne Jurriaans;Jan M. Prins

  • Pharmacokinetics of darunavir/ritonavir and TMC125 alone and coadministered in HIV-negative volunteers.

    Monika Schöller-Gyüre;Thomas N Kakuda;Vanitha Sekar;Brian Woodfall

  • Simultaneous quantitative determination of the HIV protease inhibitors amprenavir, indinavir, nelfinavir, ritonavir and saquinavir in human plasma by ion-pair high-performance liquid chromatography with ultraviolet detection

    R.P.G van Heeswijk;R.M.W Hoetelmans;R Harms;P.L Meenhorst

  • The effect of different meal types on the pharmacokinetics of darunavir (TMC114)/ritonavir in HIV-negative healthy volunteers.

    Vanitha Sekar;Dries Kestens;Sabrina Spinosa-Guzman;Martine De Pauw

  • Enhanced penetration of indinavir in cerebrospinal fluid and semen after the addition of low-dose ritonavir.

    R. M. E. Van Praag;G. J. Weverling;P. Portegies;S. Jurriaans

  • Clinical pharmacology of HIV protease inhibitors: focus on saquinavir, indinavir, and ritonavir

    R.M.W. Hoetelmans;P.L. Meenhorst;J.W. Mulder;D.M. Burger

Frequent Co-Authors

Jos H. Beijnen
Jos H. Beijnen Utrecht University
Joep M. A. Lange
Joep M. A. Lange University of Amsterdam
David M. Burger
David M. Burger Radboud University
David A. Cooper
David A. Cooper University of New South Wales
Anton Pozniak
Anton Pozniak London School of Hygiene & Tropical Medicine
Jan M. Prins
Jan M. Prins University of Amsterdam
Suzanne Jurriaans
Suzanne Jurriaans University of Amsterdam
Sven A. Danner
Sven A. Danner University of Amsterdam
Peter Reiss
Peter Reiss University of Amsterdam
Jan Mulder
Jan Mulder Norwegian University of Life Sciences

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