D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 62 Citations 13,959 127 World Ranking 4754 National Ranking 169

Research.com Recognitions

Awards & Achievements

2014 - Fellow of the Royal Society of Canada Academy of Science

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Internal medicine

His primary areas of investigation include Endothelium, Endocrinology, Internal medicine, Molecular biology and Nitric oxide synthase. His Endothelium study incorporates themes from Tumor necrosis factor alpha, Endothelial stem cell, Hypoxia and Cytokine. Philip A. Marsden studied Endocrinology and Endothelin 1 that intersect with Endothelin receptor.

His study brings together the fields of Cell and Internal medicine. His studies in Molecular biology integrate themes in fields like Histone H2A, Gene expression, Enos, Trichostatin A and ATP synthase. His studies deal with areas such as Myocyte, Complementary DNA, Molecular cloning and In situ hybridization as well as Nitric oxide synthase.

His most cited work include:

  • Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform. (905 citations)
  • Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. (774 citations)
  • Hypoxia induces endothelin gene expression and secretion in cultured human endothelium. (622 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Molecular biology, Cell biology, Internal medicine, Endocrinology and Endothelium. His Molecular biology research is multidisciplinary, relying on both Complementary DNA, Messenger RNA, Gene expression, Gene and Enos. His work on Exon, Promoter and Gene isoform is typically connected to FGL2 as part of general Gene study, connecting several disciplines of science.

His work in Cell biology addresses subjects such as Regulation of gene expression, which are connected to disciplines such as DNA methylation, Epigenetics and Neuroscience. His study in Endothelium is interdisciplinary in nature, drawing from both Endothelial stem cell, Cancer research, Immunology and In situ hybridization. He studies Nitric oxide synthase, a branch of Nitric oxide.

He most often published in these fields:

  • Molecular biology (28.89%)
  • Cell biology (25.00%)
  • Internal medicine (23.89%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cell biology (25.00%)
  • Epigenetics (12.78%)
  • DNA methylation (12.22%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Epigenetics, DNA methylation, Gene expression and Gene. His Epigenetics research includes elements of Chromatin and Disease. His DNA methylation study combines topics from a wide range of disciplines, such as Phenotype and Regulation of gene expression.

Philip A. Marsden has researched Gene expression in several fields, including microRNA and Untranslated region. Philip A. Marsden works mostly in the field of Untranslated region, limiting it down to concerns involving Gene knockdown and, occasionally, Molecular biology. His biological study deals with issues like Angiogenesis, which deal with fields such as Receptor and Biochemistry.

Between 2012 and 2021, his most popular works were:

  • Angiogenesis in Glioblastoma (130 citations)
  • Epigenetics and Cardiovascular Disease (86 citations)
  • A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity (53 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

Philip A. Marsden mainly focuses on Regulation of gene expression, Enos, Gene, DNA methylation and Angiogenesis. In his study, RNA Stability, Gene expression, MRNA destabilization, microRNA and Subcellular localization is strongly linked to Computational biology, which falls under the umbrella field of Regulation of gene expression. Biochemistry and Nitric oxide are the main areas of his Enos studies.

The various areas that Philip A. Marsden examines in his DNA methylation study include Chromatin, Histone, Epigenetics and Phenotype. His biological study spans a wide range of topics, including Glioblastoma and Cell biology. His Messenger RNA study combines topics in areas such as RNA, Molecular biology and Bioinformatics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform.

Santiago Lamas;Philip A. Marsden;Gordon K. Li;Paul Tempst.
Proceedings of the National Academy of Sciences of the United States of America (1992)

1312 Citations

Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene.

P. A. Marsden;H. H. Q. Heng;S. W. Scherer;R. J. Stewart.
Journal of Biological Chemistry (1993)

1190 Citations

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium.

S Kourembanas;P A Marsden;L P McQuillan;D V Faller.
Journal of Clinical Investigation (1991)

872 Citations

Control of cardiac muscle cell function by an endogenous nitric oxide signaling system

Jean-Luc Balligand;Ralph A. Kelly;Philip A. Marsden;Thomas W. Smith.
Proceedings of the National Academy of Sciences of the United States of America (1993)

837 Citations

Molecular cloning and characterization of human endothelial nitric oxide synthase

Philip A. Marsden;Keith T. Schappert;Hai Sheine Chen;Michele Flowers.
FEBS Letters (1992)

675 Citations

Expression of Multiple Isoforms of Nitric Oxide Synthase in Normal and Atherosclerotic Vessels

J N Wilcox;R R Subramanian;C L Sundell;W R Tracey.
Arteriosclerosis, Thrombosis, and Vascular Biology (1997)

590 Citations

Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms

Lynda P. McQuillan;Gordon K. Leung;Philip A. Marsden;Sandra K. Kostyk.
American Journal of Physiology-heart and Circulatory Physiology (1994)

551 Citations

Endothelin action on vascular smooth muscle involves inositol trisphosphate and calcium mobilization

Philip A. Marsden;N. Raju Danthuluri;Barry M. Brenner;Barbara J. Ballermann.
Biochemical and Biophysical Research Communications (1989)

404 Citations

Structural organization of the human neuronal nitric oxide synthase gene (NOS1)

A. V. Hall;H. Antoniou;Yang Wang;A. H. Cheung.
Journal of Biological Chemistry (1994)

373 Citations

Transcriptional regulation of the endothelin-1 gene by TNF-alpha.

P. A. Marsden;B. M. Brenner.
American Journal of Physiology-cell Physiology (1992)

353 Citations

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