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R. Loch Macdonald

R. Loch Macdonald

D-Index & Metrics

Medicine

D-Index
110
Citations
52606
World Ranking
5483
National Ranking
213

Overview

R. Loch Macdonald is a researcher affiliated with the University of Toronto in Canada, specializing primarily in medicine with a focus on neurology. Their scholarly work extensively covers topics related to intracranial aneurysms, traumatic brain injury, neurosurgical procedures, vascular malformations, cerebrospinal fluid disorders, and cerebrovascular diseases.

Their research spans several subfields including neurology, cellular and molecular neuroscience, pulmonary and respiratory medicine, cardiology and cardiovascular medicine, and oncology. This multidisciplinary approach reflects the complex nature of the clinical conditions studied.

Macdonald's recent publications highlight ongoing contributions to understanding subarachnoid hemorrhage and related cerebrovascular conditions. Notable papers include:

  • "Aneurysmal Subarachnoid Hemorrhage: the Last Decade" (2020), published in Translational Stroke Research
  • "Treatment of Spontaneous Subarachnoid Hemorrhage" (2020), published in Stroke
  • "Single-Dose Intraventricular Nimodipine Microparticles Versus Oral Nimodipine for Aneurysmal Subarachnoid Hemorrhage" (2020), published in Stroke
  • "Role of perivascular and meningeal macrophages in outcome following experimental subarachnoid hemorrhage" (2021), published in Journal of Cerebral Blood Flow & Metabolism
  • "Rethinking the initial changes in subarachnoid haemorrhage: Focusing on real-time metabolism during early brain injury" (2022), published in EBioMedicine

Frequent collaborators in Macdonald's research include Sean N. Neifert, Michael L. Martini, J Mocco, Nima Etminan, and José I. Suárez. These coauthors have each contributed to multiple publications alongside Macdonald, supporting a cohesive research network.

Macdonald's work is frequently published in several key journals in the neuroscience and neurosurgery domain. The most frequent publication venues are:

  • Stroke
  • Neurosurgery
  • Neurocritical Care
  • World Neurosurgery
  • bioRxiv (Cold Spring Harbor Laboratory)

The main topics addressed in Macdonald's studies include:

  • Intracranial Aneurysms: Treatment and Complications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neurosurgical Procedures and Complications
  • Vascular Malformations Diagnosis and Treatment
  • Cerebrospinal fluid and hydrocephalus
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Cerebrovascular and Carotid Artery Diseases

Best Publications

  • Guidelines for the Management of Spontaneous Intracerebral Hemorrhage. A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

    J. Claude Hemphill;Steven M. Greenberg;Craig S. Anderson;Kyra Becker

  • Guidelines for the Management of Spontaneous Intracerebral Hemorrhage

    Lewis B. Morgenstern;J. Claude Hemphill;Craig Anderson;Kyra Becker

  • Definition of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage as an Outcome Event in Clinical Trials and Observational Studies Proposal of a Multidisciplinary Research Group

    Mervyn D.I. Vergouwen;Marinus Vermeulen;Jan van Gijn;Gabriel J.E. Rinkel

  • Spontaneous subarachnoid haemorrhage

    R Loch Macdonald;R Loch Macdonald;Tom A Schweizer;Tom A Schweizer

  • It's Time to Revise the Definition of Status Epilepticus

    Daniel H. Lowenstein;Thomas P Bleck;Robert L. Macdonald

  • Cognitive and Functional Outcome After Aneurysmal Subarachnoid Hemorrhage

    Timour Al-Khindi;R. Loch Macdonald;Tom A. Schweizer

  • Prediction of symptomatic vasospasm after subarachnoid hemorrhage: the modified fisher scale.

    Jennifer A. Frontera;Jan Claassen;J. Michael Schmidt;Katja E. Wartenberg

  • Clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (CONSCIOUS-1): randomized, double-blind, placebo-controlled phase 2 dose-finding trial.

    R. Loch Macdonald;Neal F. Kassell;Stephan Mayer;Daniel Ruefenacht

  • Delayed neurological deterioration after subarachnoid haemorrhage

    R. Loch Macdonald

  • Clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid haemorrhage undergoing surgical clipping: a randomised, double-blind, placebo-controlled phase 3 trial (CONSCIOUS-2)

    R Loch Macdonald;Randall T Higashida;Emanuela Keller;Stephan A Mayer

  • Prognostic Factors for Outcome in Patients With Aneurysmal Subarachnoid Hemorrhage

    Axel J. Rosengart;Kim E. Schultheiss;Jocelyn Tolentino;R. Loch Macdonald

  • Enhanced neurosteroid potentiation of ternary GABA(A) receptors containing the delta subunit

    Kai M. Wohlfarth;Matt T. Bianchi;Robert L. Macdonald

  • Extrasynaptic GABAA Receptors: Form, Pharmacology, and Function

    Delia Belelli;Neil L. Harrison;Jamie Maguire;Robert L. Macdonald

  • Cerebral vasospasm following subarachnoid hemorrhage: time for a new world of thought.

    Ryszard M. Pluta;Jacob Hansen-Schwartz;Jens Dreier;Peter Vajkoczy

  • Rapid Seizure-Induced Reduction of Benzodiazepine and Zn2+ Sensitivity of Hippocampal Dentate Granule Cell GABAA Receptors

    Jaideep Kapur;Robert L. Macdonald

  • Cerebral vasospasm after subarachnoid hemorrhage: the emerging revolution.

    R Loch Macdonald;Ryszard M Pluta;John H Zhang

  • Differential regulation of γ-aminobutyric acid receptor channels by diazepam and phenobarbital

    Roy E. Twyman;Carl J. Rogers;Robert L. Macdonald

  • GABRD encoding a protein for extra- or peri-synaptic GABAA receptors is a susceptibility locus for generalized epilepsies

    Leanne M. Dibbens;Hua-Jun Feng;Michaella C. Richards;Louise A. Harkin

  • Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial

    Michael D Hill;Renee H Martin;David Mikulis;John H Wong

  • Subarachnoid hemorrhage grading scales: a systematic review.

    David S. Rosen;R. Loch MacDonald

Frequent Co-Authors

Tom A. Schweizer
Tom A. Schweizer St. Michael's Hospital
Bryce Weir
Bryce Weir University of Chicago
Stephan A. Mayer
Stephan A. Mayer New York Medical College
James C. Torner
James C. Torner University of Iowa
Neal F. Kassell
Neal F. Kassell Focused Ultrasound Foundation
Andreas Raabe
Andreas Raabe University of Bern
Michael M. Todd
Michael M. Todd University of Minnesota
Peter Vajkoczy
Peter Vajkoczy Charité - University Medicine Berlin
Gustavo Saposnik
Gustavo Saposnik University of Toronto
E. Sander Connolly
E. Sander Connolly Columbia University

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