World's Best Scientists 2026 revealed!

Overview

Charles Lu is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research spans a range of topics primarily within biochemistry, genetics, molecular biology, and medicine, with a focus on oncology and cancer research.

Their scholarly work engages deeply with cancer genomics and diagnostics, genomics in rare diseases, and molecular mechanisms related to RNA and protein synthesis. Additional research interests include cancer immunotherapy and biomarkers, RNA modifications associated with cancer, as well as single-cell and spatial transcriptomics.

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Biotechnology
  • Nature Communications
  • UNC Libraries
  • Journal of Investigative Dermatology

Some of Charles Lu's recent papers are:

  • Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing, 2021, Nature Biotechnology
  • Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing, 2021, Nature Biotechnology
  • Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy, 2022, Nature Communications
  • Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity, 2022, Cancer Cell
  • Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study, 2021, Scientific Data

Collaborations appear frequently with researchers including:

  • Daniel Verduzco
  • Sakina M. Petiwala
  • Michael J. Flister
  • Jiří Drábek
  • Xu Shi

The primary fields of study associated with Charles Lu's publications are biochemistry, genetics and molecular biology as well as medicine. Within these fields, subfields such as molecular biology, oncology, cancer research, genetics, and immunology appear prominently.

Best Publications

  • The cancer genome atlas pan-cancer analysis project

    John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw

  • Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer

    K Kian Ang;Jonathan Harris;Richard Wheeler;Randal Weber

  • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

    Timothy J. Ley;Christopher Miller;Li Ding;Benjamin J. Raphael

  • Mutational landscape and significance across 12 major cancer types

    Cyriac Kandoth;Michael D. McLellan;Fabio Vandin;Kai Ye

  • Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

    Li Ding;Timothy J. Ley;David E. Larson;Christopher A. Miller

  • Age-related mutations associated with clonal hematopoietic expansion and malignancies

    Mingchao Xie;Charles Lu;Jiayin Wang;Michael D McLellan

  • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

    Jinghui Zhang;Li Ding;Linda Holmfeldt;Gang Wu

  • The origin and evolution of mutations in acute myeloid leukemia.

    John S. Welch;Timothy J. Ley;Daniel C. Link;Christopher A. Miller

  • Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

    William C. Nierman;William C. Nierman;Arnab Pain;Michael J. Anderson;Jennifer R. Wortman;Jennifer R. Wortman

  • Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

    Gang Wu;Alberto Broniscer;Troy A McEachron;Charles Lu

  • Whole-genome analysis informs breast cancer response to aromatase inhibition

    Matthew J. Ellis;Li Ding;Dong Shen;Jingqin Luo

  • The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

    Gang Wu;Alexander K Diaz;Alexander K Diaz;Barbara S Paugh;Sherri L Rankin

  • Novel mutations target distinct subgroups of medulloblastoma

    Giles Robinson;Matthew Parker;Tanya A. Kranenburg;Charles Lu;Charles Lu

  • Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

    Jinghui Zhang;Gang Wu;Claudia P. Miller;Ruth G. Tatevossian

  • The genomic landscape of hypodiploid acute lymphoblastic leukemia

    Linda Holmfeldt;Lei Wei;Ernesto Diaz-Flores;Michael Walsh

  • Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts.

    Shunqiang Li;Dong Shen;Jieya Shao;Robert Crowder

  • MSIsensor: microsatellite instability detection using paired tumor-normal sequence data

    Beifang Niu;Kai Ye;Qunyuan Zhang;Charles Lu

  • Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma

    Xiang Chen;Armita Bahrami;Alberto Pappo;John Easton

  • C11orf95 – RELA fusions drive oncogenic NF-κB signalling in ependymoma

    Matthew Parker;Kumarasamypet M. Mohankumar;Chandanamali Punchihewa;Ricardo Weinlich

  • The Cancer Genome Atlas Pan-Cancer analysis project

    Kyle Chang;Chad J Creighton;Caleb Davis;Lawrence Donehower

Frequent Co-Authors

Elaine R. Mardis
Elaine R. Mardis The Ohio State University
Li Ding
Li Ding Washington University in St. Louis
Richard K. Wilson
Richard K. Wilson Nationwide Children's Hospital
Xifeng Wu
Xifeng Wu Zhejiang University
Robert S. Fulton
Robert S. Fulton Washington University in St. Louis
James R. Downing
James R. Downing St. Jude Children's Research Hospital
George R. Blumenschein
George R. Blumenschein The University of Texas MD Anderson Cancer Center
Jack A. Roth
Jack A. Roth The University of Texas MD Anderson Cancer Center
Jinghui Zhang
Jinghui Zhang St. Jude Children's Research Hospital
Margaret R. Spitz
Margaret R. Spitz Baylor College of Medicine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a career in medicine doesn’t have to begin and end with traditional medical school. There are flexible online degree options that open doors to a wide range of health professions, from patient care to research and leadership roles.

For aspiring nurses, online nursing programs offer accredited courses you can complete at your own pace, making it easier to balance studies with other commitments. Registered nurses aiming for career advancement should consider the cheapest online rn to bsn programs, which provide a cost-effective pathway to earn a Bachelor of Science in Nursing.

Those interested in advanced practice can pursue cheapest fnp programs to become a Family Nurse Practitioner, taking on greater responsibility in patient care. For leadership, education, or research-focused careers, an online nursing doctorate delivers a strong foundation for high-level roles.

Each of these online programs can help you build a rewarding medical career with greater flexibility and often lower tuition costs than traditional pathways.

Best Scientists Citing Charles Lu

Trending Scientists

Recently Published Articles