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Biology and Biochemistry

D-Index
66
Citations
18143
World Ranking
8560
National Ranking
660

Overview

Bernard Keavney is affiliated with the University of Manchester in the United Kingdom. Their research mainly spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields including Molecular Biology, Epidemiology, Cardiology and Cardiovascular Medicine, Genetics, and Pulmonary and Respiratory Medicine.

Their work covers several specific research topics with a focus on congenital heart conditions and genetic associations. Main topics include:

  • Congenital heart defects research
  • Congenital Heart Disease Studies
  • Genetic Associations and Epidemiology
  • Coronary Artery Anomalies
  • RNA modifications and cancer
  • Cardiac Valve Diseases and Treatments
  • Cancer-related molecular mechanisms research

Recent papers authored or co-authored by Bernard Keavney include:

  • Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits, 2024, Nature Genetics
  • Congenital heart disease risk loci identified by genome-wide association study in European patients, 2020, Journal of Clinical Investigation
  • Global prevalence of congenital heart disease in school-age children: a meta-analysis and systematic review, 2020, BMC Cardiovascular Disorders
  • Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney, 2021, Nature Genetics
  • Circulating ceramides as biomarkers of cardiovascular disease: Evidence from phenotypic and genomic studies, 2021, Atherosclerosis

Frequent co-authors collaborating with Bernard Keavney include:

  • Simon G. Williams
  • Heather J. Cordell
  • Maciej Tomaszewski
  • Sushant Saluja
  • Liesl Zühlke

Bernard Keavney's research has been published extensively in several recurring scientific venues. The most frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Journal of Hypertension
  • Circulation Genomic and Precision Medicine
  • Circulation

Best Publications

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Global birth prevalence of congenital heart defects 1970–2017: updated systematic review and meta-analysis of 260 studies

    Yingjuan Liu;Sen Chen;Liesl Zühlke;Graeme C Black;Graeme C Black

  • Association of apolipoprotein E genotypes with lipid levels and coronary risk.

    Anna M. Bennet;Emanuele Di Angelantonio;Zheng Ye;Frances Wensley

  • Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention.

    Michael Inouye;Gad Abraham;Christopher P. Nelson;Angela M. Wood

  • Association analyses based on false discovery rate implicate new loci for coronary artery disease.

    Christopher P Nelson;Christopher P Nelson;Anuj Goel;Anuj Goel;Adam S Butterworth;Stavroula Kanoni

  • Association of Cholesteryl Ester Transfer Protein Genotypes With CETP Mass and Activity, Lipid Levels, and Coronary Risk

    Alexander Thompson;Emanuele Di Angelantonio;Nadeem Sarwar;Sebhat Erqou

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Helen R Warren;Evangelos Evangelou;Evangelos Evangelou;Claudia P Cabrera;He Gao

  • Seven haemostatic gene polymorphisms in coronary disease : meta-analysis of 66 155 cases and 91 307 controls

    Zheng Ye;Eugene H C Liu;Julian P T Higgins;Bernard D Keavney

  • Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency

    Rachel Emma Dickinson;Helen Griffin;Venetia Bigley;Louise N. Reynard

  • Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls. International Studies of Infarct Survival (ISIS) Collaborators.

    Bernard Keavney;Colin McKenzie;Sarah Parish;Alison Palmer

  • Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing

    Alejandro Sifrim;Marc-Phillip Hitz;Anna Wilsdon;Jeroen Breckpot

  • Research capacity. Enabling the genomic revolution in Africa

    Charles Rotimi;Akin Abayomi;Alash'le Abimiku;Victoria May Adabayeri

  • Four paraoxonase gene polymorphisms in 11 212 cases of coronary heart disease and 12 786 controls: meta-analysis of 43 studies

    Jeremy G Wheeler;Bernard D Keavney;Bernard D Keavney;Hugh Watkins;Hugh Watkins;Rory Collins;Rory Collins

  • Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.

    Michael S. Cunnington;Mauro Santibanez Koref;Bongani M. Mayosi;John Burn

  • Genotype at a promoter polymorphism of the interleukin-6 gene is associated with baseline levels of plasma C-reactive protein.

    Mark A Vickers;Fiona R Green;Catherine Terry;Bongani M Mayosi

  • Genome-wide analysis identifies 12 loci influencing human reproductive behavior

    Nicola Barban;Rick Jansen;Ronald De Vlaming;Ahmad Vaez;Ahmad Vaez

  • Contribution of Global Rare Copy-Number Variants to the Risk of Sporadic Congenital Heart Disease

    Rachel Soemedi;Ian J. Wilson;Jamie Bentham;Rebecca Darlay

  • Large-scale test of hypothesised associations between the angiotensin-1 converting enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 5000 controls

    B D Keavney;C A McKenzie;S Parish;A Palmer

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (vol 49, pg 403, 2017)

    HR Warren;E Evangelou;CP Cabrera;H Gao

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelos Evangelou;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsu

Frequent Co-Authors

Hugh Watkins
Hugh Watkins University of Oxford
Martin Farrall
Martin Farrall University of Oxford
Heather J. Cordell
Heather J. Cordell Newcastle University
Bongani M. Mayosi
Bongani M. Mayosi University of Cape Town
Judith A. Goodship
Judith A. Goodship Newcastle University
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Shoumo Bhattacharya
Shoumo Bhattacharya University of Oxford
John Danesh
John Danesh University of Cambridge
Markus Perola
Markus Perola Finnish Institute for Health and Welfare
Jaspal S. Kooner
Jaspal S. Kooner Imperial College London

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