World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
64
Citations
12029
World Ranking
2964
National Ranking
1394

Overview

Daniel F. Hoft is affiliated with Saint Louis University in the United States. Their research primarily spans multiple fields, including Medicine, Immunology and Microbiology, and Biochemistry, Genetics, and Molecular Biology. Within these domains, they have contributed extensively to subfields such as Immunology, Infectious Diseases, Epidemiology, Molecular Biology, and Health.

The main topics covered by Daniel F. Hoft's research include:

  • SARS-CoV-2 and COVID-19 Research
  • Immune Cell Function and Interaction
  • Influenza Virus Research Studies
  • Tuberculosis Research and Epidemiology
  • Immune responses and vaccinations
  • Immunodeficiency and Autoimmune Disorders
  • Vaccines and immunoinformatics approaches

The scientist has published frequently in several venues. The primary publication venues include:

  • Frontiers in Immunology
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Infectious Diseases
  • Clinical Infectious Diseases

Some recent papers authored by Daniel F. Hoft include:

  • "Reprogramming lipid metabolism prevents effector T cell senescence and enhances tumor immunotherapy," 2021, Science Translational Medicine
  • "SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells," 2020, PLoS Pathogens
  • "Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools," 2020, Frontiers in Immunology
  • "Senescent T cells within suppressive tumor microenvironments: emerging target for tumor immunotherapy," 2020, Journal of Clinical Investigation
  • "NK and NKT cells have distinct properties and functions in cancer," 2021, Oncogene

Frequent coauthors in their work include:

  • Nadine Rouphael
  • Christopher S. Eickhoff
  • Sharon E. Frey
  • Evan J. Anderson
  • Azra Blazevic

Best Publications

  • Tumor Microenvironments Direct the Recruitment and Expansion of Human Th17 Cells

    Xinming Su;Jian Ye;Eddy C. Hsueh;Yanping Zhang

  • Live and Inactivated Influenza Vaccines Induce Similar Humoral Responses, but Only Live Vaccines Induce Diverse T-Cell Responses in Young Children

    Daniel F. Hoft;Elizabeth Babusis;Shewangizaw Worku;Charles T. Spencer

  • Polyclonal mucosa-associated invariant T cells have unique innate functions in bacterial infection.

    Wei-Jen Chua;Steven M. Truscott;Christopher S. Eickhoff;Azra Blazevic

  • Bacille Calmette-Guérin vaccination enhances human gamma delta T cell responsiveness to mycobacteria suggestive of a memory-like phenotype.

    Daniel F. Hoft;Robin M. Brown;Stanford T. Roodman

  • TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy

    Lingyun Li;Xia Liu;Katherine L. Sanders;James L. Edwards

  • Reprogramming lipid metabolism prevents effector T cell senescence and enhances tumor immunotherapy.

    Xia Liu;Celine L. Hartman;Lingyun Li;Carolyn J. Albert

  • Regulatory T cells trigger effector T cell DNA damage and senescence caused by metabolic competition.

    Xia Liu;Wei Mo;Jian Ye;Lingyun Li

  • Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials.

    Kayvon Modjarrad;Leyi Lin;Sarah L George;Sarah L George;Kathryn E Stephenson;Kathryn E Stephenson

  • Tumor-Infiltrating γδ T Lymphocytes Predict Clinical Outcome in Human Breast Cancer

    Chunling Ma;Qunyuan Zhang;Jian Ye;Fang Wang;Fang Wang

  • CD4+ and CD8+ T cells have opposing roles in breast cancer progression and outcome

    Yi Huang;Chunling Ma;Qunyuan Zhang;Jian Ye

  • A New Recombinant Bacille Calmette-Guérin Vaccine Safely Induces Significantly Enhanced Tuberculosis-Specific Immunity in Human Volunteers

    Daniel F. Hoft;Azra Blazevic;Getahun Abate;Willem A. Hanekom

  • Immune responses to plasmid DNA encoding the hepatitis C virus core protein.

    L. M. Lagging;K. Meyer;D. Hoft;M. Houghton

  • Tumor-derived γδ regulatory T cells suppress innate and adaptive immunity through the induction of immunosenescence.

    Jian Ye;Chunling Ma;Eddy C. Hsueh;Christopher S. Eickhoff

  • Enhancement of Innate and Cell-Mediated Immunity by Antimycobacterial Antibodies

    S. de Vallière;G. Abate;A. Blazevic;R. M. Heuertz

  • SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells.

    Tapas Patra;Keith Meyer;Lizzie Geerling;T. Scott Isbell

  • Human regulatory T cells induce T-lymphocyte senescence

    Jian Ye;Xingxu Huang;Eddy C. Hsueh;Qunyuan Zhang

  • Investigation of the relationships between immune-mediated inhibition of mycobacterial growth and other potential surrogate markers of protective Mycobacterium tuberculosis immunity.

    Daniel F. Hoft;Shewangizaw Worku;Beate Kampmann;Christopher C. Whalen

  • Use of Protein Antigens for Early Serological Diagnosis of Leprosy

    Malcolm S. Duthie;Wakako Goto;Greg C. Ireton;Stephen T. Reece

  • TLR8 signaling enhances tumor immunity by preventing tumor-induced T-cell senescence

    Jian Ye;Chunling Ma;Eddy C Hsueh;Jie Dou

  • Tuberculosis vaccine development: goals, immunological design, and evaluation.

    Daniel F Hoft

Frequent Co-Authors

Guangyong Peng
Guangyong Peng Saint Louis University
Robert B. Belshe
Robert B. Belshe Saint Louis University
Mark J. Mulligan
Mark J. Mulligan New York University
Jamie Rossjohn
Jamie Rossjohn Monash University
Nadine Rouphael
Nadine Rouphael Emory University
Willem A. Hanekom
Willem A. Hanekom University College London
Ted H. Hansen
Ted H. Hansen Washington University in St. Louis
Ranjit Ray
Ranjit Ray Saint Louis University
Lars Kjer-Nielsen
Lars Kjer-Nielsen University of Melbourne
David P. Fairlie
David P. Fairlie University of Queensland

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in immunology, pursuing advanced degrees in nursing, especially Nurse Practitioner programs, offers a promising pathway. Many professionals start with a Family Nurse Practitioner (FNP) background and then pursue acute care certification for fnp to specialize in acute care settings, which aligns well with immunology’s focus on critical and chronic conditions.

Choosing the right program can impact both career trajectory and affordability. Those looking for budget-friendly options might consider the cheapest pmhnp programs, which support advanced practice roles while keeping costs low.

Career growth is also influenced by specialty and geographic location. Nurses with Doctor of Nursing Practice degrees often seek roles that offer competitive compensation, with research into the highest paid dnp specialties providing insight into lucrative fields within healthcare.

For those eager to expedite their studies, enrolling in a nurse practitioner accelerated program can help reduce time to graduation and entry into the workforce, making it an attractive option for career changers or those aiming to specialize quickly.

Best Scientists Citing Daniel F. Hoft

Trending Scientists

Recently Published Articles