Guangyong Peng

Best Publications

• Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function.

  Gyangyong Peng;Zhong Guo;Yukiko Kiniwa;Kui Shin Voo

  980
  Citations

• Tumor-Specific Human CD4+ Regulatory T Cells and Their Ligands: Implications for Immunotherapy

  Helen Yicheng Wang;Dean A. Lee;Guangyong Peng;Zhong Guo

  707
  Citations

• Tumor-Infiltrating γδ T Cells Suppress T and Dendritic Cell Function via Mechanisms Controlled by a Unique Toll-like Receptor Signaling Pathway

  Guangyong Peng;Helen Yicheng Wang;Helen Yicheng Wang;Weiyi Peng;Weiyi Peng;Yukiko Kiniwa

  470
  Citations

• CD8+ Foxp3+ Regulatory T Cells Mediate Immunosuppression in Prostate Cancer

  Yukiko Kiniwa;Yoshihiro Miyahara;Helen Yicheng Wang;Weiyi Peng

  443
  Citations

• Tumor Microenvironments Direct the Recruitment and Expansion of Human Th17 Cells

  Xinming Su;Jian Ye;Eddy C. Hsueh;Yanping Zhang

  425
  Citations

• Generation and regulation of human CD4+ IL-17-producing T cells in ovarian cancer

  Yoshihiro Miyahara;Kunle Odunsi;Wenhao Chen;Guangyong Peng

  402
  Citations

• Exhaustion and senescence: two crucial dysfunctional states of T cells in the tumor microenvironment.

  Unknown

  391
  Citations

• TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy

  Lingyun Li;Xia Liu;Katherine L. Sanders;James L. Edwards

  249
  Citations

• Reprogramming lipid metabolism prevents effector T cell senescence and enhances tumor immunotherapy.

  Xia Liu;Celine L. Hartman;Lingyun Li;Carolyn J. Albert

  248
  Citations

• Regulatory T cells trigger effector T cell DNA damage and senescence caused by metabolic competition.

  Xia Liu;Wei Mo;Jian Ye;Lingyun Li

  244
  Citations

• Tumor-Infiltrating γδ T Lymphocytes Predict Clinical Outcome in Human Breast Cancer

  Chunling Ma;Qunyuan Zhang;Jian Ye;Fang Wang;Fang Wang

  240
  Citations

• CD4+ and CD8+ T cells have opposing roles in breast cancer progression and outcome

  Yi Huang;Chunling Ma;Qunyuan Zhang;Jian Ye

  235
  Citations

• Tumor-derived γδ regulatory T cells suppress innate and adaptive immunity through the induction of immunosenescence.

  Jian Ye;Chunling Ma;Eddy C. Hsueh;Christopher S. Eickhoff

  222
  Citations

• Recognition of a New ARTC1 Peptide Ligand Uniquely Expressed in Tumor Cells by Antigen-Specific CD4+ Regulatory T Cells

  Helen Yicheng Wang;Guangyong Peng;Zhong Guo;Ethan M. Shevach

  220
  Citations

• The Role and Regulation of Human Th17 Cells in Tumor Immunity

  Unknown

  218
  Citations

• Human regulatory T cells induce T-lymphocyte senescence

  Jian Ye;Xingxu Huang;Eddy C. Hsueh;Qunyuan Zhang

  209
  Citations

• TLR-mediated metabolic reprogramming in the tumor microenvironment: potential novel strategies for cancer immunotherapy

  Lan Huang;Huaxi Xu;Guangyong Peng

  190
  Citations

• TLR8 signaling enhances tumor immunity by preventing tumor-induced T-cell senescence

  Jian Ye;Chunling Ma;Eddy C Hsueh;Jie Dou

  190
  Citations

• Tumor-associated galectin-3 modulates the function of tumor-reactive T cells

  Weiyi Peng;Helen Yicheng Wang;Yoshihiro Miyahara;Guangyong Peng

  160
  Citations

• Granzyme A Produced by γ9δ2 T Cells Induces Human Macrophages to Inhibit Growth of an Intracellular Pathogen

  Charles T. Spencer;Getahun Abate;Isaac G. Sakala;Mei Xia

  130
  Citations