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Genetics

D-Index
63
Citations
18753
World Ranking
2859
National Ranking
1251

Overview

Albertha J.M. Walhout is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant number of publications centered around molecular biology and aging.

The scientist's recent scholarly contributions include the following papers:

  • Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor (2020, eLife)
  • Modeling tissue-relevant Caenorhabditis elegans metabolism at network, pathway, reaction, and metabolite levels (2020, Molecular Systems Biology)
  • Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells (2023, Nature)
  • Vitamin B12 produced by gut bacteria modulates cholinergic signalling (2024, Nature Cell Biology)
  • WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization (2020, bioRxiv [Cold Spring Harbor Laboratory])

Frequent co-authors collaborating with Walhout include:

  • Xuhang Li
  • L. Şafak Yılmaz
  • Olga Ponomarova
  • Hefei Zhang
  • Shivani Nanda

Walhout has published extensively in several research venues, with the most frequent being:

  • bioRxiv (Cold Spring Harbor Laboratory) with 14 publications
  • Nature with 4 publications
  • eLife with 3 publications
  • Molecular Systems Biology with 3 publications
  • Nature Communications with 2 publications

Their work spans several subfields of study including molecular biology, aging, biochemistry, genetics, and biological psychiatry.

Walhout's main research topics cover a diverse range of scientific inquiries:

  • Genetics, Aging, and Longevity in Model Organisms
  • Microbial Metabolic Engineering and Bioproduction
  • Mitochondrial Function and Pathology
  • Bioinformatics and Genomic Networks
  • Gut microbiota and health
  • Biochemical Acid Research Studies
  • Tryptophan and brain disorders

Best Publications

  • Evidence for dynamically organized modularity in the yeast protein–protein interaction network

    Jing-Dong J. Han;Nicolas Bertin;Tong Hao;Debra S. Goldberg

  • Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity

    Matthew T. Weirauch;Matthew T. Weirauch;Ally Yang;Mihai Albu;Atina G. Cote

  • Protein Interaction Mapping in C. elegans Using Proteins Involved in Vulval Development

    Albertha J. M. Walhout;Raffaella Sordella;Xiaowei Lu;James L. Hartley

  • GATEWAY recombinational cloning: application to the cloning of large numbers of open reading frames or ORFeomes.

    Albertha J.M. Walhout;Gary F. Temple;Michael A. Brasch;James L. Hartley

  • Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

    Nidhi Sahni;Song Yi;Mikko Taipale;Juan I. Fuxman Bass

  • Integrating 'omic' information: a bridge between genomics and systems biology.

    Hui Ge;Albertha J.M Walhout;Albertha J.M Walhout;Marc Vidal

  • Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression

    Lesley T. MacNeil;Albertha J.M. Walhout

  • High-throughput yeast two-hybrid assays for large-scale protein interaction mapping.

    Albertha J.M. Walhout;Marc Vidal

  • Diet-Induced Developmental Acceleration Independent of TOR and Insulin in C. elegans

    Lesley T. MacNeil;Emma Watson;H. Efsun Arda;Lihua Julie Zhu

  • A Multiparameter Network Reveals Extensive Divergence between C. elegans bHLH Transcription Factors

    Christian A. Grove;Federico De Masi;M. Inmaculada Barrasa;Daniel E. Newburger

  • The interplay between transcription factors and microRNAs in genome-scale regulatory networks.

    Natalia Julia Martinez;Albertha J. M. Walhout

  • A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity

    Natalia Julia Martinez;Maria C. Ow;M. Inmaculada Barrasa;Molly Hammell

  • Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans

    Arnab Mukhopadhyay;Bart Deplancke;Albertha J M Walhout;Heidi A Tissenbaum

  • Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity

    Natalia Julia Martinez;Maria C. Ow;John S. Reece-Hoyes;M. Inmaculada Barrasa

  • A gene-centered C. elegans protein-DNA interaction network

    Bart Deplancke;Arnab Mukhopadhyay;Wanyuan Ao;Ahmed M. Elewa

  • Interspecies Systems Biology Uncovers Metabolites Affecting C. elegans Gene Expression and Life History Traits

    Emma Watson;Lesley T. MacNeil;Ashlyn D. Ritter;L. Safak Yilmaz

  • A Gateway-Compatible Yeast One-Hybrid System

    Bart Deplancke;Denis Dupuy;Marc Vidal;Albertha J.M. Walhout

  • Using networks to measure similarity between genes: Association index selection

    Juan I Fuxman Bass;Alos Diallo;Justin Nelson;Juan M Soto

  • A compendium of Caenorhabditis elegans regulatory transcription factors: a resource for mapping transcription regulatory networks.

    John S Reece-Hoyes;Bart Deplancke;Jane Shingles;Christian A Grove

  • Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics

    Aurian P. García-González;Ashlyn D. Ritter;Shaleen Shrestha;Erik C. Andersen

Frequent Co-Authors

Marc Vidal
Marc Vidal Harvard University
Bart Deplancke
Bart Deplancke École Polytechnique Fédérale de Lausanne
Chad L. Myers
Chad L. Myers University of Minnesota
Frederick P. Roth
Frederick P. Roth Lunenfeld-Tanenbaum Research Institute
David E. Hill
David E. Hill Harvard University
Matthew T. Weirauch
Matthew T. Weirauch Cincinnati Children's Hospital Medical Center
Doreen Ware
Doreen Ware Cold Spring Harbor Laboratory
Lihua Julie Zhu
Lihua Julie Zhu University of Massachusetts Chan Medical School
Job Dekker
Job Dekker University of Massachusetts Chan Medical School
Victor R. Ambros
Victor R. Ambros University of Massachusetts Chan Medical School

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