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Katsumi Matsuzaki

Katsumi Matsuzaki

D-Index & Metrics

Chemistry

D-Index
73
Citations
20935
World Ranking
4914
National Ranking
282

Biology and Biochemistry

D-Index
75
Citations
22884
World Ranking
5259
National Ranking
342

Overview

Katsumi Matsuzaki is affiliated with Kyoto University in Japan and specializes in biochemistry, genetics, and molecular biology. Their research output includes 34 publications primarily focused on molecular biology, physiology, microbiology, cellular and molecular neuroscience, and neurology.

The scientist's main research topics cover:

  • Lipid Membrane Structure and Behavior
  • Alzheimer's disease research and treatments
  • Protein Structure and Dynamics
  • Antimicrobial Peptides and Activities
  • Extracellular vesicles in disease
  • RNA Interference and Gene Delivery
  • Supramolecular Self-Assembly in Materials

Matsuzaki's frequent coauthors include:

  • Kenichi Kawano
  • Yoshiaki Yano
  • Kiyosei Takasu
  • Yousuke Yamaoka
  • Aoi Taniguchi

They have published extensively in several venues, with multiple papers appearing in:

  • Biochimica et Biophysica Acta (BBA) - Biomembranes
  • ACS Infectious Diseases
  • Biophysical Journal
  • ACS Chemical Neuroscience
  • ChemBioChem

Key recent papers authored by Katsumi Matsuzaki include:

  • "Aβ-ganglioside interactions in the pathogenesis of Alzheimer's disease," 2020, Biochimica et Biophysica Acta (BBA) - Biomembranes
  • "Molecular Mechanism of Apoptosis by Amyloid β-Protein Fibrils Formed on Neuronal Cells," 2020, ACS Chemical Neuroscience
  • "Development of Antimicrobial Peptide-Antibiotic Conjugates to Improve the Outer Membrane Permeability of Antibiotics Against Gram-Negative Bacteria," 2022, ACS Infectious Diseases
  • "Improvement of Therapeutic Index by the Combination of Enhanced Peptide Cationicity and Proline Introduction," 2020, ACS Infectious Diseases
  • "Extracellular-Vesicle Catch-and-Release Isolation System Using a Net-Charge Invertible Curvature-Sensing Peptide," 2024, Analytical Chemistry

The research spans areas of protein interactions and membrane dynamics related to neurodegenerative diseases, antimicrobial peptide design, and innovative techniques in extracellular vesicle isolation. Their work contributes to understanding molecular mechanisms underlying disease processes and developing new therapeutic approaches.

Best Publications

  • High performance plasma amyloid-β biomarkers for Alzheimer’s disease

    Akinori Nakamura;Naoki Kaneko;Victor L Villemagne;Takashi Kato

  • Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes.

    Katsumi Matsuzaki

  • An Antimicrobial Peptide, Magainin 2, Induced Rapid Flip-Flop of Phospholipids Coupled with Pore Formation and Peptide Translocation†

    Katsumi Matsuzaki;Osamu Murase;Nobutaka Fujii;Koichiro Miyajima

  • Control of cell selectivity of antimicrobial peptides

    Katsumi Matsuzaki

  • Magainins as paradigm for the mode of action of pore forming polypeptides

    Katsumi Matsuzaki

  • Structure–activity analysis of buforin II, a histone H2A-derived antimicrobial peptide: The proline hinge is responsible for the cell-penetrating ability of buforin II

    Chan Bae Park;Kwan-Su Yi;Katsumi Matsuzaki;Mi Sun Kim

  • Relationship of membrane curvature to the formation of pores by magainin 2.

    Katsumi Matsuzaki;Ken-ichi Sugishita;Noriko Ishibe;Mayu Ueha

  • Molecular Basis for Membrane Selectivity of an Antimicrobial Peptide, Magainin 2

    Katsumi Matsuzaki;Kenichi Sugishita;Nobutaka Fujii;Koichiro Miyajima

  • Peptide Helicity and Membrane Surface Charge Modulate the Balance of Electrostatic and Hydrophobic Interactions with Lipid Bilayers and Biological Membranes

    Margitta Dathe;Michael Schümann;Torsten Wieprecht;Anett Winkler

  • Cholesterol-dependent Formation of GM1 Ganglioside-bound Amyloid β-Protein, an Endogenous Seed for Alzheimer Amyloid *

    Atsuko Kakio;Sei-ichi Nishimoto;Katsuhiko Yanagisawa;Yasunori Kozutsumi

  • Interactions of Amyloid β-Protein with Various Gangliosides in Raft-Like Membranes: Importance of GM1 Ganglioside-Bound Form as an Endogenous Seed for Alzheimer Amyloid†

    Atsuko Kakio;Sei-ichi Nishimoto;Katsuhiko Yanagisawa;Yasunori Kozutsumi

  • Interactions of an antimicrobial peptide, magainin 2, with outer and inner membranes of Gram-negative bacteria.

    Katsumi Matsuzaki;Ken-ichi Sugishita;Mitsunori Harada;Nobutaka Fujii

  • Pore formation and translocation of melittin

    K. Matsuzaki;S. Yoneyama;K. Miyajima

  • Translocation of a Channel-Forming Antimicrobial Peptide, Magainin 2, across Lipid Bilayers by Forming a Pore

    Katsumi Matsuzaki;Osamu Murase;Nobutaka Fujii;Koichiro Miyajima

  • Orientational and aggregational states of magainin 2 in phospholipid bilayers.

    Katsumi Matsuzaki;Osamu Murase;Hideaki Tokuda;Susumu Funakoshi

  • Mechanism of Synergism between Antimicrobial Peptides Magainin 2 and PGLa

    Katsumi Matsuzaki;Yasuyuki Mitani;Ken-ya Akada;Osamu Murase

  • Interactions of amyloid beta-peptide (1-40) with ganglioside-containing membranes.

    Katsumi Matsuzaki;Chiho Horikiri

  • A Seed for Alzheimer Amyloid in the Brain

    Hideki Hayashi;Nobuyuki Kimura;Haruyasu Yamaguchi;Kazuhiro Hasegawa

  • Translocation of Analogues of the Antimicrobial Peptides Magainin and Buforin across Human Cell Membranes

    Kenta Takeshima;Akinori Chikushi;Kyung-Kwon Lee;Shin Yonehara

  • Aβ polymerization through interaction with membrane gangliosides

    Katsumi Matsuzaki;Koichi Kato;Koichi Kato;Katsuhiko Yanagisawa

Frequent Co-Authors

Nobutaka Fujii
Nobutaka Fujii Kyoto University
Katsuhiko Yanagisawa
Katsuhiko Yanagisawa Japan Society for the Promotion of Science
Yoshiaki Kiso
Yoshiaki Kiso Nagahama Institute of Bio-Science and Technology
Shun Hirota
Shun Hirota Nara Institute of Science and Technology
Akira Otaka
Akira Otaka University of Tokushima
Yukihiko Sugimoto
Yukihiko Sugimoto Kumamoto University
Hironobu Naiki
Hironobu Naiki University of Fukui
Sei-ichi Nishimoto
Sei-ichi Nishimoto Kyoto University
Shiroh Futaki
Shiroh Futaki Kyoto University
Kenji Sonomoto
Kenji Sonomoto Kyushu University

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